Development Level

Tbio 14 | 11,445
Tchem 9 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
decreased body weight 1 | 161
decreased circulating serum al... 1 | 82
decreased mean corpuscular hem... 1 | 50
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
female infertility 1 | 60
increased basophil cell number 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
male infertility 1 | 123
short tibia 1 | 97

Disease

Carcinoma 19 | 11,493
atypical teratoid / rhabdoid tumor 15 | 5,112
medulloblastoma, large-cell 15 | 6,241
lung cancer 13 | 4,740
glioblastoma 12 | 5,792
ovarian cancer 12 | 8,520
group 3 medulloblastoma 11 | 4,104
osteosarcoma 11 | 7,950
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
Cancer 8 | 2,499
ependymoma 8 | 4,679
oligodendroglioma 8 | 2,850
colon cancer 7 | 1,478
lung adenocarcinoma 7 | 2,716
primitive neuroectodermal tumor 7 | 3,035
Kidney cancer 6 | 2,613
adrenocortical carcinoma 6 | 1,428
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
Endometriosis 5 | 540
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
pediatric high grade glioma 5 | 1,064
3-M syndrome 4 | 15
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
ductal carcinoma in situ 4 | 1,745
Anteverted nostril 3 | 191
Autosomal recessive predisposition 3 | 1,442
Dwarfism tall vertebrae 3 | 3
Intellectual disability 3 | 1,016
Miller-McKusick-Malvaux-Syndrome (3M Syndrome) 3 | 3
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
Silver-Russell syndrome 3 | 39
pancreatic cancer 3 | 2,398
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
Abnormality of the metaphyses 2 | 48
Breast Neoplasms 2 | 445
Broad forehead 2 | 59
Bulbous nasal tip 2 | 48
Bulbous nose 2 | 48
Bushy eyebrows 2 | 49
Decreased projection of midface 2 | 105
Defective tooth enamel 2 | 31
Delayed bone age 2 | 136
Dubowitz syndrome 2 | 13
Dystrophic tooth enamel 2 | 31
Enamel abnormalities 2 | 31
Endometrial cancer 2 | 311
Everted lower lip vermilion 2 | 54
Frontal bossing 2 | 157
Gaucher disease type 1 2 | 180
Glaucoma 2 | 239
Horizontal ribs 2 | 5
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Joint hyperflexibility 2 | 78
Late tooth eruption 2 | 61
Liver cancer 2 | 604
Long narrow head 2 | 75
Long philtrum 2 | 137
Lordosis 2 | 54
Malar flattening 2 | 129
Mammary Neoplasms 2 | 425
Micromelia 2 | 58
Midface retrusion 2 | 105
Mulibrey nanism 2 | 13
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Pointed chin 2 | 33
Potato nose 2 | 48
Prominent ear 2 | 56
Protruding ears 2 | 56
Protruding lower lip 2 | 54
Renal Cell Carcinoma 2 | 214
Scapular weakness 2 | 23
Schizophrenia 2 | 1,160
Short thorax 2 | 21
Slender, gracile long tubular bones 2 | 21
Small midface 2 | 105
Thin rib 2 | 21
Triangular face 2 | 58
Turridolichocephaly 2 | 75
ULNAR HYPOPLASIA 2 | 24
Vertical Talus 2 | 25
Winged scapula 2 | 23
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Male tissues 23 | 17,142
Skin and soft tissues 23 | 17,230
Liver and Pancreas 22 | 16,750
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

GO Process

regulation of mitotic nuclear ... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase PKMYT1 Tchem Kinase -1.27237 19.2 364
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Proliferation marker protein Ki-67 MKI67 Tbio Non-IDG -2.50106 270.3 1434
Caveolin-2 CAV2 Tbio Non-IDG -2.43448 254.2 294
Death-associated protein kinase 3 DAPK3 Tchem Kinase -1.64668 50.7 291
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Pyridoxal phosphate phosphatase PDXP Tbio Enzyme -2.37320 235.7 79
F-box/WD repeat-containing protein 5 FBXW5 Tbio Non-IDG -0.48379 3.50 107
F-box only protein 43 FBXO43 Tbio Non-IDG -1.39476 25.9 94