Development Level

Tchem 48 | 1,885
Tbio 28 | 11,178
Tdark 4 | 6,569
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 11 | 125
Kinase: IDG Consortium (Comple... 5 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal bone structure 4 | 187
decreased total body fat amoun... 4 | 207
preweaning lethality, incomple... 3 | 499
abnormal pelvic girdle bone mo... 2 | 12
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased mean corpuscular vol... 2 | 79
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal maxilla morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased caudal vertebrae num... 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased urine microalbumin l... 1 | 2
long tibia 1 | 25
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 66 | 11,192
ovarian cancer 53 | 8,297
osteosarcoma 45 | 7,766
psoriasis 34 | 6,514
medulloblastoma, large-cell 33 | 6,086
lung cancer 32 | 4,607
Cancer 28 | 2,388
glioblastoma 27 | 5,635
malignant mesothelioma 26 | 3,135
atypical teratoid / rhabdoid tumor 25 | 4,971
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,204
ependymoma 21 | 4,559
Breast cancer 19 | 3,469
Kidney cancer 19 | 2,548
group 3 medulloblastoma 19 | 4,002
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,902
non-small cell lung cancer 18 | 2,799
oligodendroglioma 18 | 2,768
pancreatic cancer 18 | 2,322
primitive neuroectodermal tumor 18 | 2,957
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,872
astrocytic glioma 15 | 2,530
adult high grade glioma 14 | 3,701
lung carcinoma 14 | 2,755
Astrocytoma, Pilocytic 13 | 3,006
Blastic phase chronic myeloid leukemia 13 | 58
Chronic Myelocytic Leukemia Accelerated Phase 13 | 59
subependymal giant cell astrocytoma 13 | 2,230
Pick disease 11 | 1,856
cystic fibrosis 11 | 1,629
dermatomyositis 11 | 941
invasive ductal carcinoma 11 | 2,867
interstitial cystitis 10 | 2,237
Intellectual disability 9 | 998
Multiple myeloma 9 | 1,296
Renal Cell Carcinoma 9 | 211
Rheumatoid arthritis 9 | 1,156
adrenocortical carcinoma 9 | 1,385
group 4 medulloblastoma 9 | 1,806
tuberculosis 9 | 1,963
Epilepsy 8 | 775
Gastrointestinal stromal tumor 8 | 62
HER2-positive carcinoma of breast 8 | 21
Pancreatic Neuroendocrine Tumor 8 | 45
acute quadriplegic myopathy 8 | 1,133
diabetes mellitus 8 | 1,683
pituitary cancer 8 | 1,915
primary pancreatic ductal adenocarcinoma 8 | 1,071
Breast Neoplasms 7 | 423
Dull intelligence 7 | 634
Low intelligence 7 | 634
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Poor school performance 7 | 634
breast carcinoma 7 | 1,589
juvenile dermatomyositis 7 | 1,147
lung adenocarcinoma 7 | 2,627
primary Sjogren syndrome 7 | 710
spina bifida 7 | 1,053
Mammary Neoplasms 6 | 403
Muscle hypotonia 6 | 562
Waldenstrons macroglobulinemia 6 | 742
astrocytoma 6 | 1,113
medulloblastoma 6 | 702
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
Atopic dermatitis 5 | 915
Congenital Epicanthus 5 | 175
Downward slant of palpebral fissure 5 | 158
Endometriosis 5 | 521
Hemangioma 5 | 69
Lung Neoplasms 5 | 217
Schizophrenia 5 | 1,136
Seizures 5 | 584
Short nose 5 | 127
Small nose 5 | 127
acute myeloid leukemia 5 | 760
ductal carcinoma in situ 5 | 1,686
pancreatic carcinoma 5 | 555
Acquired scoliosis 4 | 274
Amyotrophic lateral sclerosis 4 | 437
Curvature of spine 4 | 275
Large auricle 4 | 85
Large protruding ears 4 | 85
Large, floppy ears 4 | 85
Liver Cirrhosis, Experimental 4 | 733
Long philtrum 4 | 137
Macrotia 4 | 85
Orbital separation excessive 4 | 240
Parkinson's disease 4 | 378
Short neck 4 | 139
Skin cancer 4 | 451
Strabismus 4 | 265
atypical teratoid/rhabdoid tumor 4 | 349
colon cancer 4 | 1,428
cutaneous lupus erythematosus 4 | 1,016
nasopharyngeal carcinoma 4 | 1,024
pediatric high grade glioma 4 | 1,035
posterior fossa group B ependymoma 4 | 406
progressive supranuclear palsy 4 | 656
ulcerative colitis 4 | 1,765

Tissue

Endocrine System 80 | 18,159
Digestive Tract 79 | 17,369
Female tissues 79 | 17,400
Male tissues 78 | 17,142
Liver and Pancreas 77 | 16,750
Nervous System 77 | 16,725
Respiratory system 77 | 16,393
Skin and soft tissues 77 | 17,230
Urinary Tract 76 | 16,678
Blood and immune system 75 | 16,909
Cardiovascular System 75 | 15,192

Target Family

Kinase 56 | 634
Non-IDG 17 | 12,091
Transcription Factor 5 | 1,400
Enzyme 3 | 4,145
Epigenetic 1 | 242

GO Process

regulation of mitotic cell cyc... 82 | 82
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase 26 STK26 Tchem Kinase -1.23198 19.2 234
Serine/threonine-protein kinase pim-2 PIM2 Tchem Kinase -2.28237 187.3 304
Serine/threonine-protein kinase Nek7 NEK7 Tchem Kinase -1.31475 20.8 261
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Forkhead box protein G1 FOXG1 Tbio Transcription Factor -2.63715 438.9 214
Serine/threonine-protein kinase TAO1 TAOK1 Tchem Kinase -1.59388 36.9 221
Macrophage erythroblast attacher MAEA Tbio Non-IDG -2.88589 801.6 197
Zinc finger protein 268 ZNF268 Tbio Transcription Factor -1.36128 18.0 100
Mitogen-activated protein kinase kinase kinase 1 MAP3K1 Tbio Kinase -2.12399 119.4 334
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150