Development Level

Tbio 22 | 10,625
Tchem 9 | 1,890
Tdark 2 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
decreased total body fat amoun... 3 | 186
abnormal maxilla morphology 2 | 16
decreased body length 2 | 108
decreased lean body mass 2 | 195
decreased lumbar vertebrae num... 2 | 62
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased lean body mass 2 | 107
increased startle reflex 2 | 38
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal iris morphology 1 | 12
abnormal pelvic girdle bone mo... 1 | 11
abnormal placement of pupils 1 | 4
abnormal retinal vasculature m... 1 | 15
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
abnormal zygomatic bone morpho... 1 | 3
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased rib number 1 | 59
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hypoactivity 1 | 89
immune system phenotype 1 | 17
increased CD4-positive NK T ce... 1 | 3
increased NK T cell number 1 | 11
increased body weight 1 | 42
increased heart weight 1 | 37
increased memory-marker CD4-po... 1 | 3
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
vertebral fusion 1 | 23

Disease

ovarian cancer 22 | 8,484
osteosarcoma 16 | 7,933
psoriasis 16 | 6,685
Cancer 15 | 2,346
lung cancer 13 | 4,466
medulloblastoma, large-cell 13 | 6,234
glioblastoma 12 | 5,572
malignant mesothelioma 12 | 3,162
Breast cancer 9 | 3,094
primitive neuroectodermal tumor 9 | 3,031
atypical teratoid / rhabdoid tumor 8 | 4,369
oligodendroglioma 8 | 2,849
adrenocortical carcinoma 7 | 1,427
atypical teratoid/rhabdoid tumor 6 | 1,095
breast carcinoma 6 | 1,614
dermatomyositis 6 | 933
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
invasive ductal carcinoma 6 | 2,950
astrocytoma 5 | 1,493
ependymoma 5 | 2,514
group 3 medulloblastoma 5 | 2,254
lung adenocarcinoma 5 | 2,713
lung carcinoma 5 | 2,844
medulloblastoma 5 | 1,524
non-small cell lung cancer 5 | 2,798
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
primary Sjogren syndrome 5 | 789
subependymal giant cell astrocytoma 5 | 2,287
Carcinoma 4 | 2,147
Endometriosis 4 | 535
Multiple myeloma 4 | 1,327
diabetes mellitus 4 | 1,663
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,875
pilocytic astrocytoma 4 | 3,086
posterior fossa group B ependymoma 4 | 1,530
sonic hedgehog group medulloblastoma 4 | 1,482
Atopic dermatitis 3 | 944
Chronic obstructive pulmonary disease 3 | 146
Rheumatoid Arthritis 3 | 1,160
Small cell carcinoma of lung 3 | 45
acute quadriplegic myopathy 3 | 1,157
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
colon cancer 3 | 1,475
interstitial cystitis 3 | 2,299
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
non-small cell lung carcinoma 3 | 413
pituitary cancer 3 | 1,972
Arthritis 2 | 248
Brain Neoplasms 2 | 23
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Down syndrome 2 | 548
HIV Infections 2 | 100
Liver carcinoma 2 | 217
Mammary Neoplasms 2 | 410
Obesity 2 | 616
Pancreatic Neoplasm 2 | 79
Pulmonary function (finding) 2 | 33
Type 2 diabetes mellitus 2 | 189
Waldenstrons macroglobulinemia 2 | 765
cutaneous lupus erythematosus 2 | 1,056
cystic fibrosis 2 | 1,665
facioscapulohumeral dystrophy 2 | 286
fibroadenoma 2 | 557
gastric cancer 2 | 430
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686
Adenocarcinoma 1 | 115
Basal Cell Nevus Syndrome 1 | 4
Chloracne 1 | 32
Chromosome 17q12 deletion syndrome 1 | 15
Diabetic Retinopathy 1 | 53
Dry eye syndrome 1 | 13
Familial adenomatous polyposis 1 | 31
Fatty liver disease 1 | 84
Fibromyalgia 1 | 22
Fibrosis 1 | 40
Glioma 1 | 65
Goldenhar syndrome 1 | 19
Granulosa cell tumor 1 | 4
Kartagener Syndrome 1 | 32
Kidney cancer 1 | 118
Nasopharynx carcinoma 1 | 18
Non-alcoholic Fatty Liver Disease 1 | 40
Ocular cancer 1 | 5
PITT-HOPKINS SYNDROME 1 | 21
Paralysed 1 | 9
Placenta praevia 1 | 9
Rhabdomyosarcoma 1 | 29
Sebaceous adenoma 1 | 11
Sezary Syndrome 1 | 26
Silver-Russell syndrome 1 | 37
Streptococcal pneumonia 1 | 6

Tissue

Cardiovascular System 33 | 17,958
Digestive Tract 33 | 18,473
Endocrine System 33 | 18,512
Female tissues 33 | 18,647
Liver and Pancreas 33 | 18,136
Male tissues 33 | 17,969
Nervous System 33 | 18,561
Blood and immune system 32 | 17,995
Respiratory system 32 | 17,484
Skin and soft tissues 32 | 18,115
Urinary Tract 32 | 18,444

Target Family

Non-IDG 17 | 11,971
Kinase 7 | 634
Enzyme 4 | 4,146
Transcription Factor 4 | 1,400
Epigenetic 1 | 242

GO Process

regulation of mitotic cell cyc... 33 | 33
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Multicilin MCIDAS Tbio Non-IDG -2.00076 101.0 59
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.77104 600.5 488
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.80635 59.3 127
Dynein light chain Tctex-type 3 DYNLT3 Tbio Non-IDG -0.82512 6.34 52
Cyclin-dependent kinases regulatory subunit 1 CKS1B Tbio Enzyme -1.97697 60.3 150
Transmembrane protein 8B TMEM8B Tbio Non-IDG -1.32373 24.4 97
THAP domain-containing protein 1 THAP1 Tbio Transcription Factor -1.96148 97.6 62
Protein asunder homolog ASUN Tdark Non-IDG -1.11199 14.4 31
Serine/threonine-protein kinase pim-3 PIM3 Tchem Kinase -1.83132 71.2 78