Development Level

Tbio 31 | 11,445
Tchem 9 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased vertical activity 3 | 208
decreased total body fat amoun... 2 | 207
increased startle reflex 2 | 112
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 32 | 11,493
osteosarcoma 31 | 7,950
ovarian cancer 23 | 8,520
Cancer 20 | 2,499
psoriasis 19 | 6,694
Breast cancer 16 | 3,578
atypical teratoid / rhabdoid tumor 16 | 5,112
glioblastoma 16 | 5,792
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
Kidney cancer 15 | 2,613
pancreatic cancer 13 | 2,398
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Pick disease 10 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
astrocytic glioma 9 | 2,597
colon cancer 9 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
Rheumatoid arthritis 8 | 1,191
ependymoma 8 | 4,679
group 4 medulloblastoma 8 | 1,855
invasive ductal carcinoma 8 | 2,951
subependymal giant cell astrocytoma 8 | 2,287
Intellectual disability 7 | 1,016
Thrombocytopenia 7 | 197
hepatocellular carcinoma 7 | 547
pancreatic carcinoma 7 | 562
primitive neuroectodermal tumor 7 | 3,035
Kabuki syndrome 6 | 27
Liver cancer 6 | 604
Muscle hypotonia 6 | 571
Schizophrenia 6 | 1,160
juvenile dermatomyositis 6 | 1,187
lung carcinoma 6 | 2,843
pediatric high grade glioma 6 | 1,064
tuberculosis 6 | 2,010
Down syndrome 5 | 499
Dull intelligence 5 | 645
Immune system cancer 5 | 140
Leukemia, Myelocytic, Acute 5 | 120
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
acute myeloid leukemia 5 | 783
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
gastric cancer 5 | 459
pituitary cancer 5 | 1,972
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Anemia 4 | 365
Bladder Neoplasm 4 | 112
Bleeding time prolonged 4 | 31
Breast Neoplasms 4 | 445
Byzanthine arch palate 4 | 194
Cerebrovascular disease 4 | 238
Congenital Epicanthus 4 | 177
Delayed speech and language development 4 | 112
Ecchymosis 4 | 66
Epistaxis 4 | 43
Increased tendency to bruise 4 | 66
Isolated cases 4 | 72
Language Delay 4 | 112
Leukemia 4 | 104
Leukemia, Myeloid, Acute 4 | 105
Lymphoid leukemia 4 | 160
Mammary Neoplasms 4 | 425
Neurodevelopmental Disorders 4 | 70
Speech Delay 4 | 112
Speech impairment 4 | 112
Strabismus 4 | 270
Urinary Bladder Neoplasms 4 | 114
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
Arthritis, Juvenile 3 | 126
Attention deficit hyperactivity disorder 3 | 278
Curvature of spine 3 | 282
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Juvenile arthritis 3 | 126
Seizures 3 | 596
Upward slant of palpebral fissure 3 | 75
adrenocortical carcinoma 3 | 1,428
mucosa-associated lymphoid tissue lymphoma 3 | 484
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676

Tissue

Blood and immune system 42 | 16,909
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 20 | 12,091
Epigenetic 11 | 242
Transcription Factor 6 | 1,400
Enzyme 2 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

regulation of megakaryocyte di... 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
Histone-lysine N-methyltransferase 2E KMT2E Tbio Epigenetic -1.55313 39.2 160
Histone-lysine N-methyltransferase 2C KMT2C Tbio Epigenetic -1.87625 76.5 68
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289
Histone-lysine N-methyltransferase 2D KMT2D Tbio Epigenetic -2.08086 118.1 133
Integrin alpha-IIb ITGA2B Tclin Non-IDG -3.52120 3309.8 1170
Myosin regulatory light polypeptide 9 MYL9 Tbio Non-IDG -2.50160 301.9 289