Development Level

Tbio 48 | 11,651
Tchem 15 | 1,388
Tdark 5 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 9 | 278
decreased circulating LDL chol... 3 | 38
decreased mean platelet volume 3 | 25
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating bilirubi... 2 | 19
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
enlarged spleen 2 | 41
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased mean platelet volume 2 | 45
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged thymus 1 | 5
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased glycosylated hemoglo... 1 | 1
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 44 | 11,493
ovarian cancer 40 | 8,520
glioblastoma 28 | 5,792
medulloblastoma, large-cell 28 | 6,241
osteosarcoma 28 | 7,950
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 23 | 4,679
psoriasis 22 | 6,694
adult high grade glioma 18 | 3,801
astrocytic glioma 18 | 2,597
oligodendroglioma 18 | 2,850
Breast cancer 17 | 3,578
lung cancer 17 | 4,740
Multiple myeloma 14 | 1,332
Astrocytoma, Pilocytic 13 | 3,081
Cancer 13 | 2,499
Pick disease 13 | 1,894
diabetes mellitus 13 | 1,728
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung carcinoma 11 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Parkinson's disease 10 | 392
group 4 medulloblastoma 10 | 1,855
primitive neuroectodermal tumor 10 | 3,035
Neurodegenerative disease 9 | 414
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Alzheimer's disease 8 | 658
Autosomal recessive predisposition 8 | 1,442
Kidney cancer 8 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
tuberculosis 8 | 2,010
Schizophrenia 7 | 1,160
malignant mesothelioma 7 | 3,232
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Short stature 6 | 531
Waldenstrons macroglobulinemia 6 | 765
colon cancer 6 | 1,478
medulloblastoma 6 | 720
Dementia 5 | 175
Depressive disorder 5 | 409
Nerve Degeneration 5 | 121
Stomach Neoplasms 5 | 300
Toxic encephalopathy 5 | 141
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Epilepsy 4 | 792
Heart disease 4 | 306
Kidney disease 4 | 430
Obesity 4 | 678
Osteoporosis 4 | 363
Vascular disease 4 | 319
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
hereditary spastic paraplegia 4 | 318
lung adenocarcinoma 4 | 2,716
primary pancreatic ductal adenocarcinoma 4 | 1,109
sarcoidosis 4 | 370
spina bifida 4 | 1,074
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Brain disease 3 | 96
Carcinoma, Hepatocellular 3 | 228
Cardiomegaly 3 | 116
Cutis Laxa 3 | 39
Fatigue 3 | 182
Fetal Growth Retardation 3 | 189
Gaucher disease type 1 3 | 180
Generalized osteopenia 3 | 99
Hyperglycemia 3 | 137
Hyperreflexia 3 | 209
Hypertension 3 | 396
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Liver carcinoma 3 | 240
Low set ears 3 | 181
Mental Depression 3 | 333
Muscle Spasticity 3 | 195
Osteopenia 3 | 99
Osteopetrosis 3 | 43
Parkinson Disease 3 | 64
Renal Cell Carcinoma 3 | 214
Short nose 3 | 132
Small head 3 | 374
Small nose 3 | 132
adrenocortical carcinoma 3 | 1,428
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung carcinoma 3 | 317
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 70 | 17,369
Endocrine System 70 | 18,159
Female tissues 70 | 17,400
Male tissues 70 | 17,142
Skin and soft tissues 70 | 17,230
Blood and immune system 69 | 16,909
Cardiovascular System 69 | 15,192
Liver and Pancreas 69 | 16,750
Nervous System 69 | 16,725
Urinary Tract 69 | 16,678
Respiratory system 68 | 16,393

Target Family

Enzyme 29 | 4,145
Non-IDG 28 | 12,091
Kinase 10 | 634
Transporter 2 | 473
Epigenetic 1 | 242

GO Process

regulation of macroautophagy 70 | 70
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-32 SNX32 Tdark Non-IDG 0.35 0.28 89
V-type proton ATPase subunit B, kidney isoform ATP6V1B1 Tchem Enzyme -1.71459 43.7 251
V-type proton ATPase subunit D ATP6V1D Tbio Enzyme -1.48812 30.2 69
Vacuolar protein sorting-associated protein 35 VPS35 Tbio Non-IDG -2.02621 104.1 124
5'-AMP-activated protein kinase catalytic subunit alpha-2 PRKAA2 Tchem Kinase -1.42705 21.1 603
5'-AMP-activated protein kinase subunit gamma-1 PRKAG1 Tbio Kinase -1.00162 9.02 293
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
5'-AMP-activated protein kinase subunit beta-1 PRKAB1 Tbio Kinase -1.52519 32.5 532
Exocyst complex component 1 EXOC1 Tbio Non-IDG -1.85438 74.2 51
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331