Development Level

Tbio 10 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 15 | 11,493
atypical teratoid / rhabdoid tumor 15 | 5,112
medulloblastoma, large-cell 15 | 6,241
glioblastoma 14 | 5,792
oligodendroglioma 14 | 2,850
ependymoma 13 | 4,679
group 3 medulloblastoma 13 | 4,104
psoriasis 13 | 6,694
Intellectual disability 12 | 1,016
Schizophrenia 12 | 1,160
adult high grade glioma 12 | 3,801
astrocytic glioma 12 | 2,597
ovarian cancer 12 | 8,520
osteosarcoma 11 | 7,950
subependymal giant cell astrocytoma 10 | 2,287
Dull intelligence 9 | 645
Epilepsy 9 | 792
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Pick disease 9 | 1,894
Poor school performance 9 | 645
primitive neuroectodermal tumor 9 | 3,035
Bipolar Disorder 8 | 666
lung cancer 8 | 4,740
Astrocytoma, Pilocytic 7 | 3,081
Autistic Disorder 7 | 364
Cancer 7 | 2,499
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Parkinson's disease 7 | 392
lung carcinoma 7 | 2,843
Breast cancer 6 | 3,578
Depressive disorder 6 | 409
Seizures 6 | 596
Toxic encephalopathy 6 | 141
lung adenocarcinoma 6 | 2,716
Adenoma 5 | 167
Alzheimer's disease 5 | 658
Amyotrophic lateral sclerosis 5 | 451
Cocaine-Related Disorders 5 | 92
Huntington's disease 5 | 76
Kidney cancer 5 | 2,613
Melanoma 5 | 711
astrocytoma 5 | 1,146
pancreatic cancer 5 | 2,398
Attention deficit hyperactivity disorder 4 | 278
Autosomal recessive predisposition 4 | 1,442
Brain disease 4 | 96
Cerebrovascular disease 4 | 238
Dementia 4 | 175
Disease Models, Animal 4 | 155
Hemangioma 4 | 69
Mental Depression 4 | 333
Muscle hypotonia 4 | 571
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
malignant mesothelioma 4 | 3,232
Alcoholic Intoxication, Chronic 3 | 289
Big calvaria 3 | 147
Blepharoptosis 3 | 231
Brain Ischemia 3 | 110
Cardiac Arrhythmia 3 | 103
Cognition Disorders 3 | 32
Concave bridge of nose 3 | 195
Congenital Epicanthus 3 | 177
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Downward slant of palpebral fissure 3 | 158
Electroencephalogram abnormal 3 | 101
Fragile X syndrome 3 | 34
Gastroesophageal reflux disease 3 | 110
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Kidney disease 3 | 430
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Major Depressive Disorder 3 | 301
Melanocytic nevus 3 | 43
Mood Disorders 3 | 184
Multiple myeloma 3 | 1,332
Myoclonus 3 | 74
Neurodegenerative disease 3 | 414
Posteriorly rotated ear 3 | 61
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Substance-Related Disorders 3 | 115
Unipolar Depression 3 | 250
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Digestive Tract 19 | 17,369
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Urinary Tract 19 | 16,678
Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 9 | 12,091
Enzyme 5 | 4,145
Ion Channel 3 | 344
GPCR 2 | 408
Kinase 1 | 634

GO Process

regulation of long-term neuron... 20 | 20
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Synaptogyrin-1 SYNGR1 Tbio Non-IDG -0.91762 8.64 127
Ras-related protein Rab-8A RAB8A Tbio Enzyme -2.22872 157.9 190
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Synaptopodin SYNPO Tbio Non-IDG -2.17670 132.7 191
Neuropilin and tolloid-like protein 1 NETO1 Tbio Non-IDG -1.00021 11.6 74