Development Level

Tbio 41 | 11,651
Tchem 12 | 1,388
Tclin 8 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal bone structure 2 | 187
absent pinna reflex 2 | 23
decreased bone mineral density 2 | 126
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
female infertility 2 | 60
increased or absent threshold ... 2 | 101
preweaning lethality, complete... 2 | 979
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye pigmentation 1 | 3
abnormal eyelid morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal iris morphology 1 | 13
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal maxilla morphology 1 | 17
abnormal pupil morphology 1 | 2
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal thoracic cage shape 1 | 3
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
abnormal zygomatic bone morpho... 1 | 3
absent testes 1 | 6
cataract 1 | 92
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating thyroxin... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
sclerocornea 1 | 2
short tibia 1 | 97

Disease

Carcinoma 45 | 11,493
ovarian cancer 41 | 8,520
Cancer 33 | 2,499
psoriasis 32 | 6,694
osteosarcoma 29 | 7,950
glioblastoma 26 | 5,792
lung cancer 24 | 4,740
lung carcinoma 22 | 2,843
medulloblastoma, large-cell 20 | 6,241
cystic fibrosis 18 | 1,696
malignant mesothelioma 18 | 3,232
non-small cell lung cancer 18 | 2,890
subependymal giant cell astrocytoma 15 | 2,287
ulcerative colitis 15 | 1,819
adult high grade glioma 14 | 3,801
atypical teratoid / rhabdoid tumor 14 | 5,112
interstitial cystitis 14 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
primitive neuroectodermal tumor 14 | 3,035
Breast cancer 13 | 3,578
Kidney cancer 13 | 2,613
diabetes mellitus 13 | 1,728
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
invasive ductal carcinoma 13 | 2,951
pancreatic cancer 13 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
lung adenocarcinoma 12 | 2,716
Astrocytoma, Pilocytic 11 | 3,081
Hypertension 11 | 396
Rheumatoid arthritis 11 | 1,191
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
juvenile dermatomyositis 11 | 1,187
tuberculosis 11 | 2,010
Kidney disease 10 | 430
Obesity 10 | 678
cutaneous lupus erythematosus 10 | 1,057
ependymoma 10 | 4,679
pituitary cancer 10 | 1,972
Arthritis 9 | 290
Atherosclerosis 9 | 291
Coronary artery disease 9 | 268
Hypertensive disease 9 | 292
Schizophrenia 9 | 1,160
active ulcerative colitis 9 | 764
ductal carcinoma in situ 9 | 1,745
Atopic dermatitis 8 | 952
Heart disease 8 | 306
Leukemia 8 | 104
Liver Cirrhosis, Experimental 8 | 769
astrocytic glioma 8 | 2,597
astrocytoma 8 | 1,146
gastric carcinoma 8 | 807
oligodendroglioma 8 | 2,850
Allergic hypersensitivity disease 7 | 126
Anemia 7 | 365
Asthma 7 | 385
Multiple myeloma 7 | 1,332
Myocardial Infarction 7 | 151
Prostatic Neoplasms 7 | 495
active Crohn's disease 7 | 922
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
Crohn's disease 6 | 321
Dermatitis 6 | 157
Endometriosis 6 | 540
Inflammation 6 | 120
Multiple Sclerosis 6 | 540
adrenocortical carcinoma 6 | 1,428
dermatomyositis 6 | 966
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Amyotrophic lateral sclerosis 5 | 451
Bipolar Disorder 5 | 666
Cerebrovascular disease 5 | 238
Fever 5 | 138
Hemoglobin low 5 | 124
Inflammatory bowel disease 5 | 151
Intellectual disability 5 | 1,016
Lung disease 5 | 142
Neoplasm Invasiveness 5 | 161
acute quadriplegic myopathy 5 | 1,158
esophageal adenocarcinoma 5 | 737
group 4 medulloblastoma 5 | 1,855
mucosa-associated lymphoid tissue lymphoma 5 | 484
nasopharyngeal carcinoma 5 | 1,058
nephrosclerosis 5 | 333
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
Alzheimer's disease 4 | 658
Bladder Neoplasm 4 | 112
Brain Ischemia 4 | 110
Parkinson's disease 4 | 392
Pick disease 4 | 1,894
Reperfusion Injury 4 | 86
Waldenstrons macroglobulinemia 4 | 765
chronic rhinosinusitis 4 | 512
head and neck cancer 4 | 271
medulloblastoma 4 | 720
periodontitis 4 | 293

Tissue

Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Male tissues 61 | 17,142
Skin and soft tissues 61 | 17,230
Blood and immune system 60 | 16,909
Digestive Tract 60 | 17,369
Urinary Tract 60 | 16,678
Nervous System 58 | 16,725
Respiratory system 57 | 16,393
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 19 | 4,145
Kinase 5 | 634
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
Nuclear Receptor 2 | 48
Transporter 1 | 473

GO Process

regulation of inflammatory res... 61 | 61
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
STE20/SPS1-related proline-alanine-rich protein kinase STK39 Tbio Kinase -2.11714 148.9 575
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919
Nuclear receptor subfamily 1 group D member 2 NR1D2 Tbio Nuclear Receptor -1.77473 57.5 205
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Ubl carboxyl-terminal hydrolase 18 USP18 Tbio Enzyme -1.81381 78.4 84
Interleukin-20 IL20 Tbio Non-IDG 0.30 0.07 361
Alpha-2-HS-glycoprotein AHSG Tbio Non-IDG -3.09085 1300.3 437
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 BST1 Tbio Enzyme -1.86410 73.3 284
Caspase-5 CASP5 Tchem Enzyme -2.01445 96.1 427