Development Level

Tbio 157 | 10,625
Tdark 65 | 7,003
Tchem 13 | 1,890
Tclin 12 | 602

IMPC Term

decreased circulating glucose ... 2 | 121
abnormal femur morphology 1 | 14
abnormal pelvic girdle bone mo... 1 | 11
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased gamma-delta T cell n... 1 | 18
decreased monocyte cell number 1 | 28
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
dilated heart left ventricle 1 | 10
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hyperactivity 1 | 108
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 9
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased spleen weight 1 | 3
increased vertical activity 1 | 18

Disease

Cancer 116 | 2,346
psoriasis 112 | 6,685
diabetes mellitus 77 | 1,663
Ankylosing spondylitis 76 | 138
osteosarcoma 76 | 7,933
Hypersensitivity reaction type II disease 71 | 235
Arthritis 65 | 248
Acquired immunodeficiency syndrome 63 | 164
Uveitis 60 | 103
Behcet's disease 58 | 74
lung cancer 57 | 4,466
Juvenile rheumatoid arthritis 56 | 104
Rheumatoid Arthritis 53 | 1,160
Psoriatic arthritis 51 | 83
interstitial cystitis 49 | 2,299
cutaneous lupus erythematosus 48 | 1,056
lung carcinoma 48 | 2,844
glioblastoma 44 | 5,572
ovarian cancer 41 | 8,484
tuberculosis 40 | 1,557
Multiple Sclerosis 39 | 498
ulcerative colitis 38 | 2,087
Stevens-Johnson syndrome 37 | 78
Takayasu's arteritis 36 | 52
non-small cell lung cancer 36 | 2,798
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Kidney disease 33 | 396
lung adenocarcinoma 32 | 2,713
Anemia 30 | 252
pilocytic astrocytoma 30 | 3,086
primary Sjogren syndrome 29 | 789
invasive ductal carcinoma 28 | 2,950
medulloblastoma, large-cell 28 | 6,234
Liver disease 27 | 219
Primary immunodeficiency disease 26 | 52
Skin disease 26 | 65
Leprosy 24 | 77
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
Hemochromatosis 23 | 55
Hepatitis B 23 | 103
Human immunodeficiency virus infectious disease 23 | 92
subependymal giant cell astrocytoma 23 | 2,287
atypical teratoid / rhabdoid tumor 21 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
pediatric high grade glioma 21 | 2,712
malignant mesothelioma 20 | 3,162
pancreatic cancer 20 | 2,300
periodontitis 19 | 269
posterior fossa group A ependymoma 19 | 1,511
juvenile dermatomyositis 18 | 1,189
dermatomyositis 17 | 933
Multiple myeloma 16 | 1,327
adult high grade glioma 16 | 2,148
astrocytoma 16 | 1,493
breast carcinoma 16 | 1,614
Breast cancer 15 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
pre-eclampsia 15 | 67
Asthma 14 | 349
head and neck cancer and chronic obstructive pulmonary disease 14 | 237
mucosa-associated lymphoid tissue lymphoma 14 | 480
primary pancreatic ductal adenocarcinoma 14 | 1,271
ductal carcinoma in situ 13 | 1,745
group 4 medulloblastoma 13 | 1,875
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,031
chronic lymphosyte leukemia 12 | 232
gastric carcinoma 12 | 832
Duchenne muscular dystrophy 11 | 602
Carcinoma 10 | 2,147
Crohn's disease 10 | 304
Inflammatory bowel disease 10 | 142
active Crohn's disease 10 | 918
cystic fibrosis 10 | 1,665
nasopharyngeal carcinoma 10 | 1,056
Lung disease 9 | 132
colon cancer 9 | 1,475
esophageal adenocarcinoma 9 | 737
group 3 medulloblastoma 9 | 2,254
oligodendroglioma 9 | 2,849
sarcoidosis 9 | 358
tuberculosis and treatment for 6 months 9 | 686
IGA Glomerulonephritis 8 | 454
Malaria 8 | 140
Thrombocytopenia 8 | 105
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
ependymoma 8 | 2,514
Allergic hypersensitivity disease 7 | 123
Atherosclerosis 7 | 275
Chronic obstructive pulmonary disease 7 | 146
Coronary artery disease 7 | 240
Dermatitis 7 | 107
Influenza 7 | 142
Leukemia 7 | 88
Lymphoma 7 | 56
Pneumonia 7 | 133
interstitial lung disease 7 | 291
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
sonic hedgehog group medulloblastoma 7 | 1,482

Tissue

Blood and immune system 161 | 17,995
Digestive Tract 158 | 18,473
Female tissues 158 | 18,647
Respiratory system 157 | 17,484
Urinary Tract 156 | 18,444
Cardiovascular System 155 | 17,958
Endocrine System 155 | 18,512
Liver and Pancreas 155 | 18,136
Nervous System 155 | 18,561
Skin and soft tissues 152 | 18,115
Male tissues 150 | 17,969

Target Family

Non-IDG 240 | 11,971
Enzyme 4 | 4,146
Transcription Factor 3 | 1,400

GO Process

regulation of immune response 247 | 247
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

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