Development Level

Tbio 5 | 11,445

IMPC Phenotype

decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
increased heart weight 1 | 62

Disease

adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Melanoma 2 | 711
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid / rhabdoid tumor 2 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non primary Sjogren syndrome sicca 2 | 891
ovarian cancer 2 | 8,520
Abnormality of neutrophil physiology 1 | 1
Astrocytoma, Pilocytic 1 | 3,081
Brain disease 1 | 96
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Carcinoma 1 | 11,493
Carcinoma, Hepatocellular 1 | 228
Cardiomyopathy, Dilated 1 | 83
Cardiotoxicity 1 | 3
Cell Transformation, Neoplastic 1 | 97
Depressive disorder 1 | 409
Heart Diseases 1 | 43
Heart failure 1 | 162
Immunologic Deficiency Syndromes 1 | 113
Juvenile Myelomonocytic Leukemia 1 | 21
Leukemia, Myelomonocytic, Juvenile 1 | 20
Leukocytosis 1 | 17
Liver Cirrhosis, Experimental 1 | 769
Liver carcinoma 1 | 240
Liver diseases 1 | 87
Lymphoma 1 | 81
Major Depressive Disorder 1 | 301
Mental Depression 1 | 333
Mitochondrial complex I deficiency 1 | 46
Multiple myeloma 1 | 1,332
Neoplasm Metastasis 1 | 168
Neoplastic Cell Transformation 1 | 89
Nerve Degeneration 1 | 121
Neuroblastoma 1 | 80
Neurodegenerative disease 1 | 414
Neutrophil Immunodeficiency Syndrome 1 | 1
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
Parkinson Disease 1 | 64
Parkinson Disease 6, Autosomal Recessive Early-Onset 1 | 3
Parkinson's disease 1 | 392
Parkinsonian Disorders 1 | 56
Poor wound healing 1 | 8
Retinitis pigmentosa 47 1 | 4
Schizophrenia 1 | 1,160
Skin cancer 1 | 469
Unipolar Depression 1 | 250
Ventricular Dysfunction, Left 1 | 22
Young onset Parkinson disease 1 | 10
active ulcerative colitis 1 | 764
chorea-acanthocytosis 1 | 12
chronic kidney disease 1 | 90
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
periodontitis 1 | 293
posterior fossa group A ependymoma 1 | 468
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
spina bifida 1 | 1,074

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Enzyme 4 | 4,145
Kinase 1 | 634

GO Process

regulation of hydrogen peroxid... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
NADPH oxidase activator 1 NOXA1 Tbio Enzyme -1.24428 16.9 95
Ras-related C3 botulinum toxin substrate 2 RAC2 Tbio Enzyme -2.89402 669.8 273
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
NADPH oxidase organizer 1 NOXO1 Tbio Enzyme -1.34259 21.2 158