Development Level

Tbio 16 | 11,445
Tclin 9 | 613
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
cardiovascular system phenotyp... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
edema 1 | 59
embryonic lethality prior to t... 1 | 278
increased circulating potassiu... 1 | 29
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 22 | 11,493
psoriasis 21 | 6,694
medulloblastoma, large-cell 14 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
Heart disease 12 | 306
Kidney cancer 12 | 2,613
lung cancer 12 | 4,740
primitive neuroectodermal tumor 12 | 3,035
glioblastoma 11 | 5,792
colon cancer 10 | 1,478
adult high grade glioma 9 | 3,801
group 3 medulloblastoma 9 | 4,104
pancreatic cancer 9 | 2,398
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
Cardiac Arrhythmia 8 | 103
Hypertension 8 | 396
ependymoma 8 | 4,679
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
Cancer 7 | 2,499
Cardiomyopathy 7 | 116
Epilepsy 7 | 792
Liver cancer 7 | 604
Long QT syndrome 1 7 | 20
Schizophrenia 7 | 1,160
Seizures 7 | 596
Sudden death 7 | 16
Ventricular arrhythmia 7 | 27
diabetes mellitus 7 | 1,728
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
Atrial Fibrillation 6 | 124
Autosomal recessive predisposition 6 | 1,442
Melanoma 6 | 711
Obesity 6 | 678
Syncope 6 | 22
acute quadriplegic myopathy 6 | 1,158
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
oligodendroglioma 6 | 2,850
Brugada syndrome 5 | 29
Cardiac conduction abnormalities 5 | 78
Cardiomyopathy, Dilated 5 | 83
Cerebrovascular disease 5 | 238
Conduction disorder of the heart 5 | 79
Depressive disorder 5 | 409
Dilated cardiomyopathy 5 | 56
EKG abnormalities 5 | 78
Electrocardiogram abnormal 5 | 81
Electrocardiogram change 5 | 78
Heart conduction disease 5 | 83
Heart failure 5 | 162
Hypertensive disease 5 | 292
Mental Depression 5 | 333
Myopathy 5 | 185
Pick disease 5 | 1,894
Skin cancer 5 | 469
Tachycardia, Ventricular 5 | 22
breast carcinoma 5 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Brugada Syndrome (disorder) 4 | 15
Cardiomegaly 4 | 116
Congestive heart failure 4 | 113
Endometrial cancer 4 | 311
Familial isolated dilated cardiomyopathy 4 | 41
Hyperactive behavior 4 | 91
Intellectual disability 4 | 1,016
LEFT VENTRICULAR NONCOMPACTION 10 4 | 40
LEFT VENTRICULAR NONCOMPACTION 8 4 | 40
Long QT syndrome 4 | 39
Malignant hyperthermia 4 | 26
Myocardial Infarction 4 | 151
Prenatal onset 4 | 139
Romano-Ward Syndrome 4 | 12
Status Epilepticus 4 | 98
Sudden infant death syndrome 4 | 32
Ventricular Fibrillation 4 | 17
adrenocortical carcinoma 4 | 1,428
ductal carcinoma in situ 4 | 1,745
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Alcoholic Intoxication, Chronic 3 | 289
Atopic dermatitis 3 | 952
Creatine phosphokinase serum increased 3 | 110
Curvature of spine 3 | 282
Elevated creatine kinase 3 | 110
Mood Disorders 3 | 184
Neuropathy 3 | 261
Toxic encephalopathy 3 | 141

Tissue

Endocrine System 30 | 18,159
Digestive Tract 28 | 17,369
Male tissues 28 | 17,142
Cardiovascular System 27 | 15,192
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Skin and soft tissues 27 | 17,230
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Urinary Tract 25 | 16,678
Blood and immune system 24 | 16,909

Target Family

Non-IDG 17 | 12,091
Enzyme 4 | 4,145
Ion Channel 4 | 344
GPCR 2 | 408
Kinase 2 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

regulation of heart rate 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Myosin-7 MYH7 Tbio Non-IDG -2.64013 417.6 176