Development Level

Tbio 17 | 11,445
Tclin 9 | 613
Tchem 6 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 4 | 298
hyperactivity 3 | 148
decreased fasted circulating g... 2 | 65
increased circulating triglyce... 2 | 42
increased startle reflex 2 | 112
abnormal behavioral response t... 1 | 66
abnormal gait 1 | 69
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased cardiac stroke volum... 1 | 6
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10
tremors 1 | 39

Disease

Carcinoma 23 | 11,493
psoriasis 21 | 6,694
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
osteosarcoma 13 | 7,950
adult high grade glioma 12 | 3,801
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
lung adenocarcinoma 9 | 2,716
Breast cancer 8 | 3,578
Cardiomyopathy 8 | 116
colon cancer 8 | 1,478
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
ovarian cancer 8 | 8,520
primitive neuroectodermal tumor 8 | 3,035
Astrocytoma, Pilocytic 7 | 3,081
diabetes mellitus 7 | 1,728
lung cancer 7 | 4,740
Cancer 6 | 2,499
Schizophrenia 6 | 1,160
adrenocortical carcinoma 6 | 1,428
interstitial cystitis 6 | 2,312
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Autosomal recessive predisposition 5 | 1,442
Cardiomyopathy, Dilated 5 | 83
Dilated cardiomyopathy 5 | 56
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Familial isolated dilated cardiomyopathy 5 | 41
Hypertrophic Cardiomyopathy 5 | 117
LEFT VENTRICULAR NONCOMPACTION 10 5 | 40
LEFT VENTRICULAR NONCOMPACTION 8 5 | 40
Liver Cirrhosis, Experimental 5 | 769
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
fibroadenoma 5 | 559
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Atrial Fibrillation 4 | 124
Cardiac Arrhythmia 4 | 103
Congestive heart failure 4 | 113
Heart disease 4 | 306
Heart failure 4 | 162
Hypertension 4 | 396
Kidney cancer 4 | 2,613
Long QT syndrome 4 | 39
Muscle hypotonia 4 | 571
Vascular disease 4 | 319
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Cardiac conduction abnormalities 3 | 78
Cardiomegaly 3 | 116
Cardiomyopathies 3 | 110
Cardiomyopathy, Hypertrophic, Familial 3 | 9
Coarse facial features 3 | 108
Conduction disorder of the heart 3 | 79
Constipation 3 | 181
Delayed speech and language development 3 | 112
Depressive disorder 3 | 409
Dyschezia 3 | 135
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Hypothyroidism 3 | 122
Intellectual disability 3 | 1,016
Language Delay 3 | 112
Large bregma sutures 3 | 46
Large fontanelle 3 | 46
Large, late-closing fontanelle 3 | 46
Macroglossia 3 | 65
Myocardial Infarction 3 | 151
Myopathy 3 | 185
Speech Delay 3 | 112
Speech impairment 3 | 112
Sudden death 3 | 16
Sudden infant death syndrome 3 | 32
Thickened facial skin with coarse facial features 3 | 108
Wide bregma sutures 3 | 46
chronic rhinosinusitis 3 | 512
cystic fibrosis and chronic rhinosinusitis 3 | 214
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109
Muscular dystrophy 2 | 75
limb-girdle muscular dystrophy 2 | 37

Tissue

Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Digestive Tract 31 | 17,369
Liver and Pancreas 31 | 16,750
Skin and soft tissues 31 | 17,230
Blood and immune system 30 | 16,909
Nervous System 30 | 16,725
Cardiovascular System 29 | 15,192
Male tissues 29 | 17,142
Urinary Tract 29 | 16,678
Respiratory system 27 | 16,393

Target Family

Non-IDG 15 | 12,091
Ion Channel 7 | 344
GPCR 3 | 408
Kinase 2 | 634
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

regulation of heart contractio... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Potassium voltage-gated channel subfamily E regulatory beta subunit 5 KCNE5 Tbio Non-IDG -0.91945 8.20 84
Potassium voltage-gated channel subfamily G member 2 KCNG2 Tclin Ion Channel -0.41945 2.53 93
Transmembrane domain-containing protein TMIGD3 TMIGD3 Tchem Non-IDG 0.00000 104
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Protein S100-A1 S100A1 Tbio Non-IDG -2.47381 296.0 704
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
Cardiac phospholamban PLN Tbio Non-IDG -1.93701 85.8 365