Development Level

Tbio 2 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal pelvic girdle bone mo... 1 | 12
abnormal rib morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
narrow eye opening 1 | 12
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 3 | 11,493
medulloblastoma, large-cell 3 | 6,241
Cancer 2 | 2,499
Liver Cirrhosis, Experimental 2 | 769
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
Abdominal Pain 1 | 98
Adenocarcinoma Of Esophagus 1 | 14
Amelogenesis imperfecta type 1G 1 | 11
Aortic valve stenosis 1 | 28
Autosomal recessive Robinow syndrome 1 | 27
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Biliary tract cancer 1 | 19
Brachydactyly 1 | 156
Breast Neoplasms 1 | 445
Broad ribs 1 | 12
Bushy eyebrows 1 | 49
Carcinoma of pancreas 1 | 5
Carcinoma, Ductal, Breast 1 | 11
Cholangiocarcinoma 1 | 35
Cholecystitis 1 | 18
Class III malocclusion 1 | 78
Cone-shaped epiphyses 1 | 24
Congenital Camptodactyly 1 | 40
Convex nasal bridge 1 | 57
Craniofacial Abnormalities 1 | 151
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Diffusely thickened skin 1 | 20
Enophthalmos 1 | 75
Epistaxis 1 | 43
Familial adenomatous polyposis 1 | 32
Fine hair 1 | 42
Fused vertebrae 1 | 25
Gastrointestinal hamartomatous polyps 1 | 10
Growth mental deficiency syndrome of Myhre 1 | 1
Hamartomatous polyp 1 | 10
Hemangioma, Cavernous 1 | 20
Hematochezia 1 | 9
Hereditary hemorrhagic telangiectasia 1 | 13
Hyperopia 1 | 70
Hypertension, Portal 1 | 22
Hypertrophy of lower jaw 1 | 78
Hypokalemia 1 | 52
Hypoplasia of the maxilla 1 | 66
Hypoplastic finger 1 | 17
Hypoplastic iliac wing 1 | 19
Hypoplastic toes 1 | 29
Hypotrophic malar bone 1 | 129
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
Increased risk of pancreatic cancer 1 | 9
Increased size of mandible 1 | 78
Intermittent migraine headaches 1 | 68
Invasive Ductal Breast Carcinoma 1 | 9
Iron-Refractory Iron Deficiency Anemia 1 | 15
Israeli tick typhus 1 | 2
JUVENILE POLYPOSIS/HEREDITARY HEMORRHAGIC TELANGIECTASIA SYNDROME (disorder) 1 | 1
Juvenile polyposis syndrome 1 | 7
Liver Diseases, Parasitic 1 | 9
Malar flattening 1 | 129
Malignant neoplasm of pancreas 1 | 9
Mandibular hyperplasia 1 | 78
Maxillary retrognathia 1 | 66
Midface retrusion 1 | 105
Migraine Disorders 1 | 76
Nephrosis 1 | 21
Overriding toe 1 | 10
Pachyderma 1 | 20
Pancreatic carcinoma, familial 1 | 8
Pericardial effusion 1 | 14
Peutz-Jeghers syndrome 1 | 21
Platyspondyly 1 | 56
Polyposis, Gastric 1 | 4
Prominent nasal bridge 1 | 57
Renal fibrosis 1 | 6
Retinal disease 1 | 25
Retrusion of upper jaw bones 1 | 66
Short finger 1 | 17
Short tubular bones 1 | 22
Simple syndactyly of toes, first web space 1 | 23
Small midface 1 | 105
Somatic mutation 1 | 61
Spinal fusion 1 | 25
Spontaneous haematoma 1 | 8
Stomach cancer 1 | 30
Sunken eyes 1 | 63
Telangiectasia of the skin 1 | 39
Telangiectasis 1 | 36
Thickened calvaria 1 | 17
Thin upper lip vermilion 1 | 67
Thyroid cancer 1 | 36
Urofacial syndrome 1 | 7
Vertebral body fusion 1 | 25
Visceral angiomatosis 1 | 13
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

regulation of hair follicle de... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Histone H2A deubiquitinase MYSM1 MYSM1 Tbio Transcription Factor -1.76987 62.1 184
Heparanase HPSE Tchem Enzyme -2.97169 906.4 355