Development Level

Tbio 44 | 10,625
Tchem 5 | 1,890
Tdark 2 | 7,003

IMPC Term

decreased body weight 4 | 174
abnormal behavior 3 | 226
decreased circulating free fat... 2 | 39
decreased circulating triglyce... 2 | 83
increased body weight 2 | 42
increased mean corpuscular vol... 2 | 91
preweaning lethality, complete... 2 | 633
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal eye size 1 | 11
abnormal forced expiratory flo... 1 | 1
abnormal sleep behavior 1 | 63
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased startle reflex 1 | 48
decreased tidal volume 1 | 1
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
increased KLRG1-positive CD4-p... 1 | 2
increased blood urea nitrogen ... 1 | 44
increased circulating alkaline... 1 | 119
increased circulating creatine... 1 | 2
increased grip strength 1 | 83
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
male infertility 1 | 62
thrombocytopenia 1 | 46

Disease

ovarian cancer 36 | 8,484
osteosarcoma 24 | 7,933
atypical teratoid / rhabdoid tumor 21 | 4,369
medulloblastoma, large-cell 21 | 6,234
psoriasis 21 | 6,685
Cancer 18 | 2,346
Breast cancer 17 | 3,094
glioblastoma 17 | 5,572
lung cancer 17 | 4,466
malignant mesothelioma 14 | 3,162
non-small cell lung cancer 13 | 2,798
lung adenocarcinoma 12 | 2,713
pediatric high grade glioma 12 | 2,712
pilocytic astrocytoma 12 | 3,086
primitive neuroectodermal tumor 10 | 3,031
Multiple myeloma 9 | 1,327
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
adrenocortical carcinoma 8 | 1,427
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
invasive ductal carcinoma 8 | 2,950
astrocytic glioma 7 | 2,241
diabetes mellitus 7 | 1,663
ependymoma 7 | 2,514
juvenile dermatomyositis 7 | 1,189
lung carcinoma 7 | 2,844
oligodendroglioma 7 | 2,849
pituitary cancer 7 | 1,972
posterior fossa group A ependymoma 7 | 1,511
subependymal giant cell astrocytoma 7 | 2,287
colon cancer 6 | 1,475
cystic fibrosis 6 | 1,665
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
medulloblastoma 6 | 1,524
non primary Sjogren syndrome sicca 6 | 840
Pick disease 5 | 1,893
Rheumatoid Arthritis 5 | 1,160
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
breast carcinoma 5 | 1,614
group 3 medulloblastoma 5 | 2,254
hepatocellular carcinoma 5 | 532
primary pancreatic ductal adenocarcinoma 5 | 1,271
sonic hedgehog group medulloblastoma 5 | 1,482
tuberculosis 5 | 1,557
ulcerative colitis 5 | 2,087
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,157
chronic lymphosyte leukemia 4 | 232
pancreatic cancer 4 | 2,300
posterior fossa group B ependymoma 4 | 1,530
spina bifida 4 | 1,064
Alzheimer's disease 3 | 644
Atopic dermatitis 3 | 944
Carcinoma 3 | 2,147
Myocardial Ischemia 3 | 169
Prostatic Neoplasms 3 | 471
aldosterone-producing adenoma 3 | 664
dermatomyositis 3 | 933
ductal carcinoma in situ 3 | 1,745
facioscapulohumeral dystrophy 3 | 286
tuberculosis and treatment for 3 months 3 | 327
Adenoid Cystic Carcinoma 2 | 99
Animal Mammary Neoplasms 2 | 136
Ankylosing spondylitis 2 | 138
Arthritis 2 | 248
Cardiomegaly 2 | 66
Duchenne muscular dystrophy 2 | 602
Endometriosis 2 | 535
Hydrolethalus syndrome 2 | 128
Liver Cirrhosis, Experimental 2 | 108
Liver diseases 2 | 66
Malignant neoplasm of prostate 2 | 67
Mammary Neoplasms 2 | 410
Melanoma 2 | 261
Multiple Sclerosis 2 | 498
Myocardial Infarction 2 | 126
Neoplasm Invasiveness 2 | 127
Prader-Willi syndrome 2 | 45
Stuttering 2 | 18
Vascular disease 2 | 281
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 780
adrenocortical adenoma 2 | 134
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cutaneous lupus erythematosus 2 | 1,056
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 430
gastric carcinoma 2 | 832
glioblastoma multiforme 2 | 347
interstitial lung disease 2 | 291
non-inflammatory breast cancer 2 | 208
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
periodontitis 2 | 269
tuberculosis and treatment for 6 months 2 | 686
Angelman syndrome 1 | 38

Tissue

Digestive Tract 51 | 18,473
Nervous System 51 | 18,561
Blood and immune system 50 | 17,995
Cardiovascular System 50 | 17,958
Endocrine System 50 | 18,512
Female tissues 50 | 18,647
Liver and Pancreas 50 | 18,136
Male tissues 50 | 17,969
Skin and soft tissues 50 | 18,115
Urinary Tract 50 | 18,444
Respiratory system 49 | 17,484

Target Family

Non-IDG 38 | 11,971
Epigenetic 5 | 242
Enzyme 4 | 4,146
Transcription Factor 3 | 1,400
Kinase 1 | 634

GO Process

regulation of growth 51 | 51
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Transcription factor E4F1 E4F1 Tbio Transcription Factor -1.47845 33.6 74
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.00271 1072.1 392
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.00237 102.5 132
Inhibitor of growth protein 2 ING2 Tbio Epigenetic -1.47891 33.6 155
Bromodomain-containing protein 8 BRD8 Tbio Epigenetic -0.58943 5.02 106
Malignant T-cell-amplified sequence 1 MCTS1 Tbio Non-IDG -0.68460 4.88 118
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.16682 13.8 196
Inhibitor of growth protein 3 ING3 Tbio Epigenetic -2.29256 191.2 148
Amino-terminal enhancer of split AES Tbio Non-IDG -2.09975 129.5 242