Development Level

Tbio 49 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased body weight 3 | 161
abnormal eye morphology 2 | 68
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal eating behavior 1 | 1
abnormal embryo size 1 | 220
abnormal eye size 1 | 7
abnormal forced expiratory flo... 1 | 1
abnormal sleep behavior 1 | 70
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
decreased tidal volume 1 | 1
enlarged heart 1 | 210
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased caudal vertebrae num... 1 | 7
increased circulating alkaline... 1 | 122
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

ovarian cancer 37 | 8,520
Carcinoma 33 | 11,493
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 22 | 6,241
Cancer 21 | 2,499
atypical teratoid / rhabdoid tumor 21 | 5,112
psoriasis 21 | 6,694
Breast cancer 19 | 3,578
glioblastoma 18 | 5,792
ependymoma 17 | 4,679
lung cancer 17 | 4,740
group 3 medulloblastoma 15 | 4,104
malignant mesothelioma 15 | 3,232
non-small cell lung cancer 13 | 2,890
Astrocytoma, Pilocytic 12 | 3,081
adult high grade glioma 12 | 3,801
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 10 | 3,035
tuberculosis 10 | 2,010
Multiple myeloma 9 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
adrenocortical carcinoma 8 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
lung carcinoma 8 | 2,843
subependymal giant cell astrocytoma 8 | 2,287
astrocytic glioma 7 | 2,597
diabetes mellitus 7 | 1,728
juvenile dermatomyositis 7 | 1,187
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
Kidney cancer 6 | 2,613
Pick disease 6 | 1,894
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
hepatocellular carcinoma 6 | 547
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non primary Sjogren syndrome sicca 6 | 891
Rheumatoid arthritis 5 | 1,191
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
pediatric high grade glioma 5 | 1,064
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
Alzheimer's disease 4 | 658
Endometriosis 4 | 540
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
chronic lymphosyte leukemia 4 | 204
group 4 medulloblastoma 4 | 1,855
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
Atopic dermatitis 3 | 952
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Myocardial Ischemia 3 | 169
Neoplasm Invasiveness 3 | 161
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Short stature 3 | 531
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
facioscapulohumeral dystrophy 3 | 288
sonic hedgehog group medulloblastoma 3 | 467
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Alcoholic Intoxication, Chronic 2 | 289
Arthritis 2 | 290
Bipolar Disorder 2 | 666
Carcinoma, Adenoid Cystic 2 | 99
Curvature of spine 2 | 282
Delayed speech and language development 2 | 112
Duchenne muscular dystrophy 2 | 601
Language Delay 2 | 112
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Osteoarthritis 2 | 184
Pectus excavatum 2 | 100
Specific learning disability 2 | 47
Speech Delay 2 | 112
Speech impairment 2 | 112
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
adrenocortical adenoma 2 | 131
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
gastric carcinoma 2 | 807
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293

Tissue

Digestive Tract 54 | 17,369
Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Liver and Pancreas 54 | 16,750
Male tissues 54 | 17,142
Nervous System 54 | 16,725
Skin and soft tissues 54 | 17,230
Urinary Tract 54 | 16,678
Blood and immune system 53 | 16,909
Respiratory system 53 | 16,393
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 41 | 12,091
Epigenetic 5 | 242
Enzyme 4 | 4,145
Transcription Factor 3 | 1,400
Kinase 1 | 634

GO Process

regulation of growth 54 | 54
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Transmembrane protein 8B TMEM8B Tbio Non-IDG -1.34736 25.6 106
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.22763 14.8 224
Inhibitor of growth protein 3 ING3 Tbio Epigenetic -2.33680 199.4 175
Testis-specific Y-encoded-like protein 5 TSPYL5 Tbio Non-IDG -0.97896 9.36 76
Low-density lipoprotein receptor-related protein 12 LRP12 Tbio Non-IDG -0.57984 4.31 145
Breast cancer metastasis-suppressor 1-like protein BRMS1L Tbio Non-IDG -1.71309 57.0 107
BTB/POZ domain-containing protein KCTD21 KCTD21 Tbio Non-IDG 0.60 0.27 84
Ecto-NOX disulfide-thiol exchanger 2 ENOX2 Tbio Non-IDG -1.14149 16.1 125
Chondroitin sulfate proteoglycan 5 CSPG5 Tbio Non-IDG -2.55925 360.8 181