Development Level

Tbio 52 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
decreased body weight 1 | 161
decreased circulating sodium l... 1 | 22
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating free fat... 1 | 20
increased startle reflex 1 | 112
polycystic kidney 1 | 15

Disease

Carcinoma 41 | 11,493
ovarian cancer 34 | 8,520
lung cancer 31 | 4,740
osteosarcoma 28 | 7,950
group 3 medulloblastoma 23 | 4,104
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 20 | 5,112
Kidney cancer 17 | 2,613
glioblastoma 17 | 5,792
primitive neuroectodermal tumor 13 | 3,035
psoriasis 13 | 6,694
Breast cancer 12 | 3,578
Multiple myeloma 12 | 1,332
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
astrocytic glioma 11 | 2,597
dermatomyositis 11 | 966
ependymoma 11 | 4,679
acute quadriplegic myopathy 10 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
oligodendroglioma 10 | 2,850
Pick disease 9 | 1,894
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 9 | 2,951
breast carcinoma 8 | 1,638
lung adenocarcinoma 8 | 2,716
colon cancer 7 | 1,478
Cancer 6 | 2,499
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
subependymal giant cell astrocytoma 6 | 2,287
Amyotrophic lateral sclerosis 5 | 451
Astrocytoma, Pilocytic 5 | 3,081
Rheumatoid arthritis 5 | 1,191
acute myeloid leukemia 5 | 783
ductal carcinoma in situ 5 | 1,745
hepatocellular carcinoma 5 | 547
pancreatic cancer 5 | 2,398
pancreatic carcinoma 5 | 562
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
Hereditary spherocytosis type 5 4 | 12
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
sonic hedgehog group medulloblastoma 4 | 467
Autosomal recessive predisposition 3 | 1,442
Down syndrome 3 | 499
Intellectual disability 3 | 1,016
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
ulcerative colitis 3 | 1,819
Alcoholic Intoxication, Chronic 2 | 289
Animal Mammary Neoplasms 2 | 136
Autonomic nervous system disorders 2 | 19
Brain disease 2 | 96
Chronic obstructive pulmonary disease 2 | 184
Cockayne syndrome 2 | 60
Cognitive delay 2 | 608
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Dysarthria 2 | 192
Dysautonomia 2 | 20
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
HIV Infections 2 | 102
Leukemia 2 | 104
Liver cancer 2 | 604
Low intelligence 2 | 645
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Mesothelioma, Malignant 2 | 105
Muscle Weakness 2 | 170
Neurodegenerative disease 2 | 414
Optic Atrophy 2 | 242
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Seizures 2 | 596
Short stature 2 | 531
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
gastric cancer 2 | 459
gastric carcinoma 2 | 807
inflammatory breast cancer 2 | 286
interstitial lung disease 2 | 298
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung carcinoma 2 | 317
progressive supranuclear palsy 2 | 676
triple-A syndrome 2 | 17

Tissue

Blood and immune system 55 | 16,909
Endocrine System 55 | 18,159
Female tissues 55 | 17,400
Nervous System 55 | 16,725
Respiratory system 55 | 16,393
Urinary Tract 55 | 16,678
Cardiovascular System 54 | 15,192
Digestive Tract 54 | 17,369
Liver and Pancreas 54 | 16,750
Male tissues 54 | 17,142
Skin and soft tissues 54 | 17,230

Target Family

Non-IDG 39 | 12,091
Enzyme 16 | 4,145
Epigenetic 1 | 242

GO Process

regulation of gene silencing b... 56 | 56
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
DNA-directed RNA polymerases I, II, and III subunit RPABC2 POLR2F Tbio Enzyme -1.13403 13.9 68
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.23703 17.9 139
DNA-directed RNA polymerases I, II, and III subunit RPABC4 POLR2K Tbio Enzyme -0.90716 7.36 65
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.13403 13.5 180
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -1.04073 10.5 78
DNA-directed RNA polymerases I, II, and III subunit RPABC5 POLR2L Tbio Enzyme -1.12793 13.8 66