Development Level

Tbio 9 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613

IMPC Phenotype

decreased lean body mass 3 | 135
preweaning lethality, incomple... 3 | 499
increased total body fat amoun... 2 | 134
abnormal embryo size 1 | 220
abnormal rib morphology 1 | 10
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased erythrocyte cell num... 1 | 62
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased grip strength 1 | 41

Disease

Carcinoma 13 | 11,493
Cancer 6 | 2,499
Kidney cancer 6 | 2,613
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Beckwith-Wiedemann syndrome 5 | 44
Intellectual disability 5 | 1,016
Schizophrenia 5 | 1,160
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Cryptorchidism 4 | 296
Silver-Russell syndrome 4 | 39
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Cognitive delay 3 | 608
Dental abnormalities 3 | 60
Depressive disorder 3 | 409
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Muscle hypotonia 3 | 571
Short stature 3 | 531
Tooth Abnormalities 3 | 69
atypical teratoid / rhabdoid tumor 3 | 5,112
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
psoriasis 3 | 6,694
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Advanced bone age 2 | 35
Alzheimer's disease 2 | 658
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Autistic Disorder 2 | 364
Big calvaria 2 | 147
Bilateral fifth finger clinodactyly 2 | 110
Blepharophimosis 2 | 70
Breast Neoplasms 2 | 445
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Hepatocellular 2 | 228
Cardiomegaly 2 | 116
Cardiomyopathies 2 | 110
Coarse facial features 2 | 108
Constipation 2 | 181
Craniofacial Abnormalities 2 | 151
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Dyschezia 2 | 135
Epilepsy 2 | 792
Exophthalmos 2 | 112
Gonadoblastoma 2 | 34
Growth Disorders 2 | 35
Hepatomegaly 2 | 285
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Lymphoma, T-Cell, Cutaneous 2 | 22
Macroglossia 2 | 65
Mammary Neoplasms 2 | 425
Neonatal hypoglycemia 2 | 17
Nephroblastoma 2 | 51
Penile hypospadias 2 | 106
Prominent back of the head 2 | 21
Prominent eyes 2 | 96
Prominent globes 2 | 96
Prominent occiput 2 | 21
Prostate cancer 2 | 175
Protruding eyes 2 | 96
Rheumatoid arthritis 2 | 1,191
Thickened facial skin with coarse facial features 2 | 108
Transient neonatal diabetes mellitus 2 | 14
Wide bregma sutures 2 | 46
X- linked recessive 2 | 110
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
immunodeficiency-centromeric instability-facial anomalies syndrome 2 | 16
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010

Tissue

Blood and immune system 16 | 16,909
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Nervous System 16 | 16,725
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Non-IDG 3 | 12,091
Enzyme 2 | 4,145
TF/Epigenetic 2 | 38
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

regulation of gene expression ... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
Zinc finger protein 57 homolog ZFP57 Tbio Transcription Factor -1.62133 0.00000 136
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Transcriptional repressor CTCFL CTCFL Tbio Transcription Factor -1.80632 44.8 164
Lysine-specific histone demethylase 1B KDM1B Tbio Epigenetic -1.45110 27.6 106
Transcriptional repressor CTCF CTCF Tbio Transcription Factor -2.87726 746.5 284
AT-rich interactive domain-containing protein 4B ARID4B Tbio TF/Epigenetic -1.25831 18.5 133
AT-rich interactive domain-containing protein 4A ARID4A Tbio TF/Epigenetic -1.35592 21.4 51
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
DNA (cytosine-5)-methyltransferase 3-like DNMT3L Tbio Enzyme -1.95555 87.2 403