Development Level

Tbio 64 | 10,625
Tchem 14 | 1,890
Tdark 9 | 7,003
Tclin 5 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, incomple... 4 | 260
decreased circulating alkaline... 2 | 41
decreased circulating triglyce... 2 | 83
decreased monocyte cell number 2 | 28
increased circulating triglyce... 2 | 24
preweaning lethality, complete... 2 | 633
abnormal bone mineralization 1 | 55
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal tooth morphology 1 | 24
decreased B cell number 1 | 30
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased mature B cell number 1 | 25
enlarged heart 1 | 111
female infertility 1 | 34
hydrops fetalis 1 | 22
increased IgG1 level 1 | 1
increased T cell number 1 | 15
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
male infertility 1 | 62
microphthalmia 1 | 15
tremors 1 | 34

Disease

ovarian cancer 45 | 8,484
glioblastoma 41 | 5,572
medulloblastoma, large-cell 41 | 6,234
osteosarcoma 40 | 7,933
psoriasis 37 | 6,685
lung cancer 33 | 4,466
Cancer 32 | 2,346
oligodendroglioma 31 | 2,849
pediatric high grade glioma 26 | 2,712
pilocytic astrocytoma 26 | 3,086
atypical teratoid / rhabdoid tumor 23 | 4,369
malignant mesothelioma 22 | 3,162
primitive neuroectodermal tumor 21 | 3,031
Breast cancer 19 | 3,094
Carcinoma 19 | 2,147
ependymoma 18 | 2,514
lung carcinoma 17 | 2,844
astrocytic glioma 16 | 2,241
astrocytoma 16 | 1,493
group 4 medulloblastoma 16 | 1,875
pituitary cancer 16 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
juvenile dermatomyositis 15 | 1,189
group 3 medulloblastoma 14 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
invasive ductal carcinoma 14 | 2,950
subependymal giant cell astrocytoma 14 | 2,287
adult high grade glioma 13 | 2,148
pancreatic cancer 13 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Pick disease 12 | 1,893
colon cancer 12 | 1,475
cystic fibrosis 12 | 1,665
ulcerative colitis 12 | 2,087
Alzheimer's disease 11 | 644
lung adenocarcinoma 11 | 2,713
non-small cell lung cancer 11 | 2,798
posterior fossa group B ependymoma 11 | 1,530
Prostatic Neoplasms 10 | 471
acute quadriplegic myopathy 10 | 1,157
adrenocortical carcinoma 10 | 1,427
diabetes mellitus 10 | 1,663
ductal carcinoma in situ 10 | 1,745
medulloblastoma 10 | 1,524
tuberculosis 10 | 1,557
Adenoma 9 | 165
Multiple myeloma 9 | 1,327
Obesity 9 | 616
acute myeloid leukemia 9 | 780
sonic hedgehog group medulloblastoma 9 | 1,482
Hypertensive disease 8 | 193
Mammary Neoplasms 8 | 410
Rheumatoid Arthritis 8 | 1,160
atypical teratoid/rhabdoid tumor 8 | 1,095
breast carcinoma 8 | 1,614
gastric carcinoma 8 | 832
interstitial cystitis 8 | 2,299
Amyotrophic Lateral Sclerosis 7 | 431
Lung Neoplasms 7 | 171
dermatomyositis 7 | 933
nasopharyngeal carcinoma 7 | 1,056
non-small cell lung carcinoma 7 | 413
sarcoidosis 7 | 358
Duchenne muscular dystrophy 6 | 602
Kidney disease 6 | 396
Liver disease 6 | 219
Multiple Sclerosis 6 | 498
Waldenstrons macroglobulinemia 6 | 765
aldosterone-producing adenoma 6 | 664
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 557
posterior fossa group A ependymoma 6 | 1,511
Atherosclerosis 5 | 275
Atopic dermatitis 5 | 944
Autistic Disorder 5 | 320
Cardiovascular system disease 5 | 194
Cerebrovascular disease 5 | 231
Coronary artery disease 5 | 240
Hypertension 5 | 287
Leukemia, Myelocytic, Acute 5 | 113
Neoplasm Metastasis 5 | 138
Osteoporosis 5 | 257
Polycystic Ovary Syndrome 5 | 332
Small cell carcinoma of lung 5 | 45
Vascular disease 5 | 281
active Crohn's disease 5 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
non primary Sjogren syndrome sicca 5 | 840
primary pancreatic ductal adenocarcinoma 5 | 1,271
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Endometriosis 4 | 535
Hypersensitivity reaction type II disease 4 | 235
Male infertility 4 | 170
Spontaneous abortion 4 | 108
mucosa-associated lymphoid tissue lymphoma 4 | 480
nephrosclerosis 4 | 329
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
tuberculosis and treatment for 6 months 4 | 686

Tissue

Digestive Tract 90 | 18,473
Endocrine System 90 | 18,512
Female tissues 90 | 18,647
Liver and Pancreas 90 | 18,136
Nervous System 90 | 18,561
Blood and immune system 89 | 17,995
Skin and soft tissues 89 | 18,115
Urinary Tract 89 | 18,444
Cardiovascular System 88 | 17,958
Male tissues 88 | 17,969
Respiratory system 87 | 17,484

Target Family

Non-IDG 52 | 11,971
Transcription Factor 15 | 1,400
Enzyme 14 | 4,146
Kinase 7 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341

GO Process

regulation of gene expression 92 | 92
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.63360 51.0 128
Myb/SANT-like DNA-binding domain-containing protein 1 MSANTD1 Tdark Non-IDG 0.00000 22
Tapasin TAPBP Tbio Non-IDG -2.50535 373.6 134
ATP-dependent RNA helicase DDX3Y DDX3Y Tbio Enzyme -1.73057 61.1 142
Storkhead-box protein 1 STOX1 Tbio Non-IDG -1.21152 18.3 31
Tissue-resident T-cell transcription regulator protein ZNF683 ZNF683 Tbio Transcription Factor -1.27888 19.8 35