Development Level

Tbio 76 | 11,651
Tchem 18 | 1,388
Tdark 7 | 6,593
Tclin 5 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 4 | 979
abnormal embryo size 3 | 220
edema 3 | 59
decreased circulating alkaline... 2 | 46
increased erythrocyte cell num... 2 | 39
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
anophthalmia 1 | 33
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mature B cell number 1 | 7
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased anti-nuclear antigen... 1 | 19
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 70 | 11,493
ovarian cancer 51 | 8,520
glioblastoma 48 | 5,792
psoriasis 46 | 6,694
osteosarcoma 45 | 7,950
medulloblastoma, large-cell 43 | 6,241
lung cancer 41 | 4,740
Cancer 36 | 2,499
ependymoma 36 | 4,679
group 3 medulloblastoma 33 | 4,104
atypical teratoid / rhabdoid tumor 31 | 5,112
oligodendroglioma 31 | 2,850
Astrocytoma, Pilocytic 30 | 3,081
adult high grade glioma 30 | 3,801
Breast cancer 29 | 3,578
malignant mesothelioma 26 | 3,232
primitive neuroectodermal tumor 25 | 3,035
astrocytic glioma 20 | 2,597
group 4 medulloblastoma 19 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung carcinoma 19 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
pituitary cancer 18 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Kidney cancer 16 | 2,613
invasive ductal carcinoma 16 | 2,951
pancreatic cancer 16 | 2,398
subependymal giant cell astrocytoma 16 | 2,287
Pick disease 15 | 1,894
juvenile dermatomyositis 15 | 1,187
tuberculosis 15 | 2,010
lung adenocarcinoma 14 | 2,716
astrocytoma 13 | 1,146
colon cancer 13 | 1,478
cystic fibrosis 13 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
pediatric high grade glioma 13 | 1,064
Autosomal recessive predisposition 12 | 1,442
Dull intelligence 12 | 645
Intellectual disability 12 | 1,016
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
acute myeloid leukemia 12 | 783
adrenocortical carcinoma 12 | 1,428
ductal carcinoma in situ 12 | 1,745
non-small cell lung cancer 12 | 2,890
Hypertensive disease 11 | 292
Multiple myeloma 11 | 1,332
Schizophrenia 11 | 1,160
breast carcinoma 11 | 1,638
diabetes mellitus 11 | 1,728
Adenoma 10 | 167
Alzheimer's disease 10 | 658
Prostatic Neoplasms 10 | 495
interstitial cystitis 10 | 2,312
ulcerative colitis 10 | 1,819
Epilepsy 9 | 792
Liver Cirrhosis, Experimental 9 | 769
Obesity 9 | 678
Rheumatoid arthritis 9 | 1,191
Short stature 9 | 531
acute quadriplegic myopathy 9 | 1,158
Breast Neoplasms 8 | 445
Low set ears 8 | 181
Osteoporosis 8 | 363
Weight decreased 8 | 103
aldosterone-producing adenoma 8 | 665
dermatomyositis 8 | 966
nasopharyngeal carcinoma 8 | 1,058
Amyotrophic lateral sclerosis 7 | 451
Atopic dermatitis 7 | 952
Cardiovascular Diseases 7 | 59
Cardiovascular system disease 7 | 246
Cataract 7 | 297
Endometriosis 7 | 540
Hypertension 7 | 396
Hypoplastic mandible condyle 7 | 275
Lens Opacities 7 | 231
Liver cancer 7 | 604
Lung Neoplasms 7 | 232
Mammary Neoplasms 7 | 425
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Muscle hypotonia 7 | 571
Seizures 7 | 596
Waldenstrons macroglobulinemia 7 | 765
esophageal adenocarcinoma 7 | 737
sarcoidosis 7 | 370
Duchenne muscular dystrophy 6 | 601
Male infertility 6 | 206
Multiple Sclerosis 6 | 540
Type 2 diabetes mellitus 6 | 272
Vascular disease 6 | 319
active ulcerative colitis 6 | 764
atypical teratoid/rhabdoid tumor 6 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
fibroadenoma 6 | 559
gastric carcinoma 6 | 807

Tissue

Endocrine System 104 | 18,159
Digestive Tract 103 | 17,369
Skin and soft tissues 102 | 17,230
Female tissues 101 | 17,400
Urinary Tract 101 | 16,678
Liver and Pancreas 100 | 16,750
Male tissues 99 | 17,142
Blood and immune system 98 | 16,909
Nervous System 98 | 16,725
Respiratory system 95 | 16,393
Cardiovascular System 88 | 15,192

Target Family

Non-IDG 53 | 12,091
Kinase 19 | 634
Transcription Factor 16 | 1,400
Enzyme 14 | 4,145
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Process

regulation of gene expression 106 | 106
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase MAK MAK Tchem Kinase -1.20155 15.2 266
Insulinoma-associated protein 1 INSM1 Tbio Transcription Factor -2.56531 362.4 56
Stabilin-2 STAB2 Tbio Non-IDG -2.81864 640.7 72
SHC-transforming protein 4 SHC4 Tbio Non-IDG -2.45096 295.5 129
Amyloid-beta A4 precursor protein-binding family A member 2 APBA2 Tbio Non-IDG -1.60681 41.4 135
ATP-dependent RNA helicase DDX19A DDX19A Tdark Enzyme 0.02 0.99 63
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.58850 3826.5 295
ATP-dependent RNA helicase DDX19B DDX19B Tbio Enzyme -1.25103 10.1 252
Guanine nucleotide exchange factor VAV2 VAV2 Tbio Non-IDG -1.81793 64.6 227
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.31332 2140.4 983