Development Level

Tbio 7 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
decreased circulating calcium ... 1 | 36
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 31
increased circulating total pr... 1 | 28

Disease

Carcinoma 8 | 11,493
Astrocytoma, Pilocytic 6 | 3,081
ovarian cancer 6 | 8,520
non-small cell lung cancer 5 | 2,890
Breast cancer 4 | 3,578
Cancer 4 | 2,499
cystic fibrosis 4 | 1,696
glioblastoma 4 | 5,792
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
Bipolar Disorder 3 | 666
Cleft Palate 3 | 271
Cryptorchidism 3 | 296
Dental Enamel Hypoplasia 3 | 43
Generalized osteopenia 3 | 99
Osteopenia 3 | 99
Schizophrenia 3 | 1,160
Short stature 3 | 531
Uranostaphyloschisis 3 | 167
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Abnormality of the ribs 2 | 32
Acquired metabolic disease 2 | 336
Brachydactyly 2 | 156
Byzanthine arch palate 2 | 194
Chronic otitis media 2 | 52
Class III malocclusion 2 | 78
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Craniofacial Abnormalities 2 | 151
Craniosynostosis 2 | 74
Deafness 2 | 198
Decreased projection of maxilla 2 | 66
Decreased projection of midface 2 | 105
Deficiency of upper jaw bones 2 | 66
Dental caries 2 | 164
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Frontal bossing 2 | 157
Hearing Loss, Partial 2 | 185
Holoprosencephaly 2 | 56
Hypertrophy of lower jaw 2 | 78
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypoplasia of the maxilla 2 | 66
Hypotrophic malar bone 2 | 129
Hypotrophic maxilla 2 | 66
Hypotrophic midface 2 | 105
Increased size of mandible 2 | 78
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Late tooth eruption 2 | 61
Liver cancer 2 | 604
Low Vision 2 | 174
Malar flattening 2 | 129
Mandibular hyperplasia 2 | 78
Maxillary retrognathia 2 | 66
Mental Depression 2 | 333
Midface retrusion 2 | 105
Narrow internal auditory canal 2 | 8
Narrow thorax 2 | 53
Night blindness, congenital stationary 2 | 16
Osteoporosis 2 | 363
Respiratory distress 2 | 43
Retrusion of upper jaw bones 2 | 66
Rotting teeth 2 | 73
Seizures 2 | 596
Small midface 2 | 105
Small testicle 2 | 75
Strabismus 2 | 270
Tooth Abnormalities 2 | 69
Visual Impairment 2 | 174
Wide bregma sutures 2 | 46
X-linked cerebral adrenoleukodystrophy 2 | 116
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
ear infection chronic 2 | 52
glioblastoma multiforme 2 | 142
hearing impairment 2 | 199
mandibular excess (physical finding) 2 | 78
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064

Tissue

Endocrine System 8 | 18,159
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Enzyme 3 | 4,145
Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Process

regulation of fibroblast growt... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Dual specificity protein phosphatase 6 DUSP6 Tbio Enzyme -2.22889 183.5 379
Extracellular serine/threonine protein kinase FAM20C FAM20C Tbio Enzyme -2.32591 210.3 90
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 LRIT3 Tbio Non-IDG -0.43688 4.17 64
Homeobox protein OTX2 OTX2 Tbio Transcription Factor -2.48486 317.0 248
Fibroblast growth factor receptor 2 FGFR2 Tclin Kinase -3.08664 1210.6 948