Development Level

Tbio 11 | 11,445
Tchem 6 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating choleste... 1 | 66
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19

Disease

Carcinoma 13 | 11,493
ovarian cancer 11 | 8,520
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
Cancer 6 | 2,499
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
adult high grade glioma 4 | 3,801
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
Anemia 2 | 365
Ataxia telangiectasia 2 | 34
Atopic dermatitis 2 | 952
Bloom syndrome 2 | 29
Decreased platelet count 2 | 111
Dilated ventricles (finding) 2 | 121
Endometriosis 2 | 540
Fanconi anemia 2 | 56
Leukopenia 2 | 72
Liver cancer 2 | 604
Nijmegen breakage syndrome 2 | 24
Obesity 2 | 678
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Small head 2 | 374
Thrombocytopenia 2 | 197
Xeroderma pigmentosum 2 | 43
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
hypopigmented skin patch 2 | 59
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of the lymphatic system 1 | 14
Advanced bone age 1 | 35
Bone marrow hypocellularity 1 | 20
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Renal Cell 1 | 124
Cardiomegaly 1 | 116
Dental caries 1 | 164
Dry skin 1 | 75
Dyskeratosis congenita 1 | 24
Esophageal Stenosis 1 | 15
Freckles 1 | 33
Gingival Diseases 1 | 19
Glioma 1 | 74
Hair shaft abnormalities 1 | 30
Hereditary Melanoma 1 | 12
Hyperpigmented macules 1 | 42
Hypodontia 1 | 81
Irregular hyperpigmentation 1 | 33
Leukokeratosis 1 | 19
Leukoplakia, Oral 1 | 20
Lymphatic Diseases 1 | 14
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 13
Nevus 1 | 19
Periodontal Diseases 1 | 21
Precocious Puberty 1 | 28
Renal Cell Carcinoma 1 | 214
Skin Ulcer 1 | 48
Tall stature 1 | 34
Taurodontism 1 | 14
Telangiectasia of the skin 1 | 39
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
Xerosis 1 | 75
hair abnormalities (non-specific) 1 | 30
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 17 | 16,909
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Nervous System 17 | 16,725
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Digestive Tract 16 | 17,369
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Enzyme 7 | 4,145
Non-IDG 7 | 12,091
Epigenetic 3 | 242
Kinase 1 | 634

GO Process

regulation of double-strand br... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Regulator of telomere elongation helicase 1 RTEL1 Tbio Enzyme -2.66156 233.0 85
Telomeric repeat-binding factor 2-interacting protein 1 TERF2IP Tchem Non-IDG -0.75509 5.75 308
Protein ZNF365 ZNF365 Tbio Non-IDG -1.44015 50.6 273
Testis-expressed protein 15 TEX15 Tbio Non-IDG -1.05372 9.87 11
Putative fidgetin-like protein 2 FIGNL2 Tdark Enzyme 0.00000 0
DNA repair-scaffolding protein SPIDR Tbio Non-IDG -0.75333 5.57 24
Serine/threonine-protein kinase Chk1 CHEK1 Tchem Kinase -3.04423 1089.6 1375
Ubiquitin carboxyl-terminal hydrolase 51 USP51 Tbio Enzyme -0.06160 1.35 22
Fidgetin FIGN Tbio Enzyme -1.34015 21.2 103