Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal allantois morphology 1 | 8
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thin ventricular wall 1 | 24

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
atypical teratoid / rhabdoid tumor 8 | 5,112
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
adult high grade glioma 7 | 3,801
glioblastoma 7 | 5,792
group 3 medulloblastoma 6 | 4,104
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
ependymoma 5 | 4,679
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
astrocytic glioma 4 | 2,597
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
Liver cancer 3 | 604
breast carcinoma 3 | 1,638
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Autistic Disorder 2 | 364
DOID:2627 2 | 94
Epilepsy 2 | 792
Intellectual disability 2 | 1,016
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
subependymal giant cell astrocytoma 2 | 2,287
Adenoid Cystic Carcinoma 1 | 99
Angelman syndrome 1 | 34
Broad forehead 1 | 59
Bulging forehead 1 | 66
COPD 1 | 118
Carcinoma, Adenoid Cystic 1 | 99
Cerebellar hypoplasia and atrophy 1 | 41
Cerebral atrophy 1 | 178
Congenital deafness 1 | 185
Constipation 1 | 181
Deafness 1 | 198
Dementia 1 | 175
Developmental regression 1 | 95
Dilated ventricles (finding) 1 | 121
Dyschezia 1 | 135
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1 1 | 5
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Electroencephalogram abnormal 1 | 101
Epilepsies, Myoclonic 1 | 32
Flexion contracture of proximal interphalangeal joint 1 | 75
Gastroesophageal reflux disease 1 | 110
Generalized myoclonic seizures 1 | 30
Hearing Loss, Partial 1 | 185
Heartburn 1 | 78
Hemolytic anemia 1 | 77
Hyperventilation 1 | 6
Hypsarrhythmia 1 | 25
Infantile onset 1 | 238
Large intestine cancer 1 | 126
Loss of developmental milestones 1 | 95
Lymphoid leukemia 1 | 160
Mental deterioration in childhood 1 | 95
Microcephaly 1 | 166
Muscle Spasticity 1 | 195
Myoclonic Epilepsies, Progressive 1 | 44
Neurodevelopmental regression 1 | 95
Optic nerve disease 1 | 10
Peripartum cardiomyopathy 1 | 4
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Prominent forehead 1 | 66
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Stereotyped Behavior 1 | 37
Stereotypic Movement Disorder 1 | 42
Tapering fingers (finding) 1 | 25
Thalassemia 1 | 53
Trichorhinophalangeal syndrome type II 1 | 15
Warburg micro syndrome 1 | 18
West Syndrome 1 | 28
Wide nose 1 | 35
X-linked dominant 1 | 57
hearing impairment 1 | 199
interstitial lung disease 1 | 298
sarcoidosis 1 | 370

Tissue

Blood and immune system 11 | 16,909
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Digestive Tract 10 | 17,369
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400

GO Process

regulation of dendrite develop... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
B-cell lymphoma/leukemia 11A BCL11A Tbio Transcription Factor -2.16270 151.0 300
Protein very KIND KNDC1 Tdark Non-IDG -0.08517 1.17 53
CUB and sushi domain-containing protein 3 CSMD3 Tbio Non-IDG -0.91740 6.87 50
Calmodulin-regulated spectrin-associated protein 2 CAMSAP2 Tbio Non-IDG -0.81458 5.80 37
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein PREX1 Tbio Non-IDG -1.50424 44.7 163
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.60409 401.5 393
Reticulon-4-interacting protein 1, mitochondrial RTN4IP1 Tbio Enzyme -1.69878 47.3 145
Cyclin-dependent kinase-like 5 CDKL5 Tchem Kinase -2.14512 140.1 195
Calcium/calmodulin-dependent protein kinase type 1D CAMK1D Tchem Kinase -1.19277 13.2 313
Ras-related protein Rab-17 RAB17 Tbio Enzyme -1.25057 20.8 158