Development Level

Tbio 15 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal retina morphology 1 | 71
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
prolonged QRS complex duration 1 | 8
sclerocornea 1 | 2
short tibia 1 | 97

Disease

ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
osteosarcoma 12 | 7,950
Breast cancer 10 | 3,578
Cancer 10 | 2,499
glioblastoma 9 | 5,792
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
group 3 medulloblastoma 7 | 4,104
malignant mesothelioma 7 | 3,232
Kidney cancer 6 | 2,613
ependymoma 5 | 4,679
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Breast Neoplasms 4 | 445
Liver cancer 4 | 604
Mammary Neoplasms 4 | 425
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Pick disease 3 | 1,894
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
posterior fossa group A ependymoma 3 | 468
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Carcinoma of colon 2 | 32
Carcinoma, Renal Cell 2 | 124
Centronuclear myopathy 2 | 27
Ciliopathy 2 | 71
Colorectal Neoplasms 2 | 243
Endometrial cancer 2 | 311
Large intestine cancer 2 | 126
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Waldenstrons macroglobulinemia 2 | 765
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
Aphakia, congenital primary 1 | 5
Attention Deficit Disorder with Hyperactivity 1 | 21
Autosomal recessive nonsyndromic deafness 48 1 | 1
BILIARY TRACT ABNORMALITY 1 | 16
Bardet-Biedl syndrome 4 1 | 1
Bardet-Biedl syndrome 4 (disorder) 1 | 1
Biliary Tract Diseases 1 | 16
Broad feet 1 | 19
Choroidal sclerosis 1 | 8
Cone dystrophy 1 | 71
Cystic kidney 1 | 30
Esophageal atresia 1 | 43
Fibrosis, Liver 1 | 32
Fundus dystrophy 1 | 83
Gait imbalance 1 | 17
Irregular hyperpigmentation 1 | 33
Lewy Body Disease 1 | 21
Lynch syndrome 1 | 35
Malignant tumor of prostate 1 | 26
Nephroblastoma 1 | 51
Nephrogenic Diabetes Insipidus 1 | 16
Peripheral Neuropathy 1 | 134
Poor coordination 1 | 11
Precocious Puberty 1 | 28
Premature Menopause 1 | 31
Renal cyst 1 | 30
Small testicle 1 | 75
Tracheoesophageal Fistula 1 | 36
Wilms Tumor 1 | 28
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 13 | 12,091
Kinase 4 | 634
Enzyme 3 | 4,145
Epigenetic 1 | 242

GO Process

regulation of cytokinesis 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
ARF GTPase-activating protein GIT1 GIT1 Tbio Enzyme -1.84352 75.7 358
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Pyridoxal phosphate phosphatase PDXP Tbio Enzyme -2.37320 235.7 79
Serine/threonine-protein kinase PLK3 PLK3 Tchem Kinase -1.92921 94.0 185
Serologically defined colon cancer antigen 3 SDCCAG3 Tdark Non-IDG -0.27564 2.95 84
Baculoviral IAP repeat-containing protein 6 BIRC6 Tbio Non-IDG -1.79775 61.4 168