Development Level

Tbio 18 | 10,625

IMPC Term

preweaning lethality, complete... 2 | 633
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187

Disease

ovarian cancer 10 | 8,484
osteosarcoma 7 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
Multiple myeloma 5 | 1,327
medulloblastoma, large-cell 5 | 6,234
dermatomyositis 4 | 933
lung cancer 4 | 4,466
psoriasis 4 | 6,685
Breast cancer 3 | 3,094
Cancer 3 | 2,346
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,157
atypical teratoid / rhabdoid tumor 3 | 4,369
ependymoma 3 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
non primary Sjogren syndrome sicca 3 | 840
oligodendroglioma 3 | 2,849
pancreatic cancer 3 | 2,300
Atopic dermatitis 2 | 944
Carcinoma 2 | 2,147
IGA Glomerulonephritis 2 | 454
Neurodegenerative disease 2 | 383
Pick disease 2 | 1,893
Tuberous sclerosis 2 | 18
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
glioblastoma 2 | 5,572
group 3 medulloblastoma 2 | 2,254
interstitial cystitis 2 | 2,299
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,713
malignant mesothelioma 2 | 3,162
primary Sjogren syndrome 2 | 789
primary pancreatic ductal adenocarcinoma 2 | 1,271
primitive neuroectodermal tumor 2 | 3,031
sonic hedgehog group medulloblastoma 2 | 1,482
spina bifida 2 | 1,064
ulcerative colitis 2 | 2,087
Amyotrophic Lateral Sclerosis 1 | 431
Anterior ischemic optic neuropathy 1 | 7
Aphasia 1 | 22
Basal cell carcinoma 1 | 29
Bipolar Disorder 1 | 266
Bloom syndrome 1 | 30
Brain glioma 1 | 10
Cataract 1 | 104
Celiac disease 1 | 112
Cholangitis 1 | 20
Chromosome 2p16.1-p15 deletion syndrome 1 | 6
Degenerative polyarthritis 1 | 93
Dementia 1 | 129
Dentin dysplasia 1 | 19
Epithelial ovarian cancer 1 | 19
Esophageal Neoplasms 1 | 67
Esophageal varix 1 | 10
Frontotemporal dementia 1 | 41
Head and Neck Neoplasms 1 | 23
Hypersplenism 1 | 9
Hypertension 1 | 287
Influenza 1 | 142
Intraocular pressure disorder 1 | 8
Kidney cancer 1 | 118
Kidney disease 1 | 396
Leukemia, Myelocytic, Acute 1 | 113
Liver disease 1 | 219
Malaria 1 | 140
Malignant neoplasm of ovary 1 | 13
Mammary Neoplasms 1 | 410
Mammary Neoplasms, Experimental 1 | 150
Melanoma 1 | 261
Mesothelioma 1 | 40
Multiple Sclerosis 1 | 498
Neoplasm Invasiveness 1 | 127
Oligohydramnios 1 | 18
Organ system cancer 1 | 15
PONTOCEREBELLAR HYPOPLASIA, TYPE 8 1 | 1
Polycystic kidney disease 1 | 54
Polycystic liver disease 1 | 10
Pontocerebellar hypoplasia 1 | 29
Portal hypertension 1 | 21
Prostate cancer 1 | 172
Restless legs syndrome 1 | 28
Skin Neoplasms 1 | 49
Stomach Neoplasms 1 | 282
Xeroderma pigmentosum 1 | 41
adrenocortical adenoma 1 | 134
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
diabetes mellitus 1 | 1,663
inflammatory breast cancer 1 | 404
interstitial lung disease 1 | 291
medulloblastoma 1 | 1,524
non-small cell lung cancer 1 | 2,798
ovarian neoplasm 1 | 97
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
progressive supranuclear palsy 1 | 674
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 18 | 17,995
Cardiovascular System 18 | 17,958
Digestive Tract 18 | 18,473
Endocrine System 18 | 18,512
Female tissues 18 | 18,647
Liver and Pancreas 18 | 18,136
Male tissues 18 | 17,969
Nervous System 18 | 18,561
Respiratory system 18 | 17,484
Skin and soft tissues 18 | 18,115
Urinary Tract 18 | 18,444

Target Family

Non-IDG 16 | 11,971
Enzyme 2 | 4,146

GO Process

regulation of centrosome dupli... 18 | 18
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.65708 53.0 166
Ras-related protein Rab-6C RAB6C Tbio Enzyme -0.76901 8.37 71
Charged multivesicular body protein 1b CHMP1B Tbio Non-IDG -0.76435 3.98 62
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.45589 286.4 377
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.73095 61.0 81
Fibrocystin PKHD1 Tbio Non-IDG -2.66291 478.8 63
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.42758 268.0 77
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.14262 14.2 135
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.51550 30.4 192
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG 32.7 58