Development Level

Tbio 48 | 10,625
Tchem 21 | 1,890
Tdark 4 | 7,003
Tclin 2 | 602

IMPC Phenotype

preweaning lethality, complete... 8 | 633
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
abnormal snout morphology 2 | 18
increased grip strength 2 | 83
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal iris morphology 1 | 12
abnormal joint morphology 1 | 14
abnormal maxilla morphology 1 | 16
abnormal optic disc morphology 1 | 10
abnormal placement of pupils 1 | 4
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal tooth morphology 1 | 24
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
increased body weight 1 | 42
increased circulating LDL chol... 1 | 15
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
male infertility 1 | 62
narrow eye opening 1 | 15
short tibia 1 | 82
tremors 1 | 34

Disease

ovarian cancer 49 | 8,491
osteosarcoma 41 | 7,933
lung cancer 33 | 4,473
medulloblastoma, large-cell 33 | 6,234
glioblastoma 26 | 5,572
psoriasis 25 | 6,685
atypical teratoid / rhabdoid tumor 24 | 4,369
Cancer 23 | 2,346
Breast cancer 21 | 3,098
group 3 medulloblastoma 19 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
oligodendroglioma 18 | 2,849
Carcinoma 15 | 2,147
dermatomyositis 15 | 966
malignant mesothelioma 15 | 3,163
pediatric high grade glioma 15 | 2,712
primitive neuroectodermal tumor 15 | 3,031
Pick disease 14 | 1,893
Waldenstrons macroglobulinemia 14 | 764
astrocytic glioma 13 | 2,241
ependymoma 13 | 2,514
astrocytoma 12 | 1,493
non-small cell lung cancer 12 | 2,798
Multiple myeloma 11 | 1,327
acute quadriplegic myopathy 11 | 1,157
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
invasive ductal carcinoma 11 | 2,950
pilocytic astrocytoma 11 | 3,086
Rheumatoid Arthritis 10 | 1,170
sonic hedgehog group medulloblastoma 10 | 1,482
adult high grade glioma 9 | 2,148
colon cancer 9 | 1,475
diabetes mellitus 9 | 1,663
subependymal giant cell astrocytoma 9 | 2,287
Prostatic Neoplasms 8 | 471
esophageal adenocarcinoma 8 | 737
lung adenocarcinoma 8 | 2,714
pancreatic cancer 8 | 2,300
HIV Infections 7 | 99
Parkinson's disease 7 | 364
Vascular disease 7 | 281
atypical teratoid/rhabdoid tumor 7 | 1,095
breast carcinoma 7 | 1,614
ductal carcinoma in situ 7 | 1,745
non primary Sjogren syndrome sicca 7 | 840
posterior fossa group B ependymoma 7 | 1,530
spina bifida 7 | 1,064
ulcerative colitis 7 | 2,087
Amyotrophic Lateral Sclerosis 6 | 432
Atopic dermatitis 6 | 944
Mammary Neoplasms 6 | 410
Obesity 6 | 616
group 4 medulloblastoma 6 | 1,875
interstitial cystitis 6 | 2,299
juvenile dermatomyositis 6 | 1,189
medulloblastoma 6 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
tuberculosis and treatment for 6 months 6 | 686
Stomach Neoplasms 5 | 282
acute myeloid leukemia 5 | 785
cystic fibrosis 5 | 1,670
lung carcinoma 5 | 2,844
pituitary cancer 5 | 1,972
tuberculosis and treatment for 3 months 5 | 327
Alzheimer's disease 4 | 644
Cocaine-Related Disorders 4 | 88
Huntington's disease 4 | 72
Intellectual disability 4 | 573
Kidney cancer 4 | 121
Myopathy 4 | 128
Neoplasm Metastasis 4 | 138
Neurodegenerative disease 4 | 383
Schizophrenia 4 | 503
Squamous cell carcinoma 4 | 96
adrenocortical carcinoma 4 | 1,427
hepatocellular carcinoma 4 | 550
hereditary spastic paraplegia 4 | 313
interstitial lung disease 4 | 292
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
Adenoid Cystic Carcinoma 3 | 99
Arthritis 3 | 248
Atherosclerosis 3 | 275
Bipolar Disorder 3 | 266
Bladder Neoplasm 3 | 109
Hyperalgesia 3 | 71
Kidney disease 3 | 397
Melanoma 3 | 261
Metabolic syndrome X 3 | 155
Multiple Sclerosis 3 | 498
Nijmegen breakage syndrome 3 | 23
chronic lymphocytic leukemia 3 | 244
cystic fibrosis and chronic rhinosinusitis 3 | 213
gastric cancer 3 | 436
nasopharyngeal carcinoma 3 | 1,056
ovarian neoplasm 3 | 97
primary pancreatic ductal adenocarcinoma 3 | 1,271
progressive supranuclear palsy 3 | 674
tuberculosis 3 | 1,563

Tissue

Blood and immune system 75 | 17,994
Cardiovascular System 75 | 17,957
Endocrine System 75 | 18,511
Female tissues 75 | 18,646
Liver and Pancreas 75 | 18,135
Male tissues 75 | 17,968
Nervous System 75 | 18,560
Digestive Tract 74 | 18,472
Respiratory system 74 | 17,483
Skin and soft tissues 74 | 18,114
Urinary Tract 74 | 18,443

Target Family

Non-IDG 55 | 11,969
Kinase 11 | 634
Enzyme 4 | 4,146
Epigenetic 3 | 242
Transcription Factor 2 | 1,400

GO Process

regulation of cellular respons... 75 | 75
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.63849 5.23 31
Target of rapamycin complex subunit LST8 MLST8 Tbio Non-IDG -2.61267 401.4 319
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.26734 207.5 1100
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.18826 15.9 128
BAG family molecular chaperone regulator 4 BAG4 Tbio Non-IDG -1.32573 23.7 264
Heat shock protein HSP 90-alpha HSP90AA1 Tchem Non-IDG -3.28941 4395.5 921
Aladin AAAS Tbio Non-IDG -3.23885 1684.2 137
Heat shock factor-binding protein 1 HSBP1 Tbio Non-IDG -0.97962 10.3 61
Nucleoporin Nup43 NUP43 Tdark Non-IDG 0.12 1.06 119
Nucleoporin Nup37 NUP37 Tdark Non-IDG -0.46724 2.97 51