Development Level

Tbio 40 | 11,445
Tclin 6 | 613
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavioral response t... 1 | 66
abnormal kidney morphology 1 | 65
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ovarian cancer 39 | 8,520
Multiple myeloma 29 | 1,332
lung cancer 26 | 4,740
psoriasis 24 | 6,694
osteosarcoma 19 | 7,950
Carcinoma 18 | 11,493
HIV Infections 16 | 102
glioblastoma 15 | 5,792
dermatomyositis 12 | 966
Waldenstrons macroglobulinemia 11 | 765
Breast cancer 10 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Cancer 9 | 2,499
diabetes mellitus 9 | 1,728
invasive ductal carcinoma 9 | 2,951
ependymoma 8 | 4,679
atypical teratoid / rhabdoid tumor 7 | 5,112
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
malignant mesothelioma 7 | 3,232
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
astrocytoma 6 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
subependymal giant cell astrocytoma 6 | 2,287
Liver Cirrhosis, Experimental 5 | 769
Mantle cell lymphoma 5 | 23
lung adenocarcinoma 5 | 2,716
non primary Sjogren syndrome sicca 5 | 891
oligodendroglioma 5 | 2,850
Osteoporosis 4 | 363
Pick disease 4 | 1,894
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
cutaneous lupus erythematosus 4 | 1,057
pancreatic cancer 4 | 2,398
primary Sjogren syndrome 4 | 735
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Obesity 3 | 678
Vascular disease 3 | 319
astrocytic glioma 3 | 2,597
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
Acute kidney injury 2 | 70
Alzheimer's disease 2 | 658
Amenorrhea 2 | 58
Anemia 2 | 365
Animal Mammary Neoplasms 2 | 136
Arthrogryposis 2 | 54
Barrett's esophagus 2 | 182
Bladder Neoplasm 2 | 112
Colorectal Neoplasms 2 | 243
Congestive heart failure 2 | 113
Contact Dermatitis 2 | 81
Dermatitis, Contact 2 | 71
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Diarrhea 2 | 253
Esophageal Squamous Cell Carcinoma 2 | 77
Failure to gain weight 2 | 365
Fatty Liver 2 | 70
Heart failure 2 | 162
Hyperglycemia 2 | 137
Hyperthyroidism 2 | 53
Hypogonadism 2 | 173
Hypothyroidism 2 | 122
Lipodystrophy 2 | 40
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Muscle Weakness 2 | 170
Papilloma 2 | 44
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Peripheral Neuropathy 2 | 134
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Squamous cell carcinoma of esophagus 2 | 77
Unipolar Depression 2 | 250
Urinary Bladder Neoplasms 2 | 114
active Crohn's disease 2 | 922
chronic kidney disease 2 | 90
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
maturity-onset diabetes of the young 2 | 32
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Acute coronary syndrome 1 | 39
Hepatocellular Adenoma 1 | 10
Hyperostosis 1 | 18
Hyperprolactinemia 1 | 27
Metabolic Syndrome 1 | 20
Paranoid personality disorder 1 | 5

Tissue

Endocrine System 52 | 18,159
Blood and immune system 51 | 16,909
Digestive Tract 51 | 17,369
Female tissues 51 | 17,400
Nervous System 51 | 16,725
Respiratory system 51 | 16,393
Urinary Tract 51 | 16,678
Cardiovascular System 50 | 15,192
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Skin and soft tissues 50 | 17,230

Target Family

Enzyme 45 | 4,145
Non-IDG 7 | 12,091

GO Process

regulation of cellular amino a... 52 | 52
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
26S proteasome regulatory subunit 10B PSMC6 Tbio Enzyme -2.65165 339.0 214
Proteasome subunit alpha type-7 PSMA7 Tbio Enzyme -2.71627 496.7 288
Proteasome subunit alpha type-6 PSMA6 Tbio Enzyme -2.80973 614.4 288
26S proteasome complex subunit SEM1 SEM1 Tbio Non-IDG -2.83524 645.6 109
26S proteasome non-ATPase regulatory subunit 11 PSMD11 Tbio Enzyme -1.13234 13.3 211
Proteasome subunit alpha type-3 PSMA3 Tbio Enzyme -1.20981 15.8 181