Development Level

Tbio 102 | 11,445
Tchem 19 | 1,598
Tclin 9 | 613
Tdark 7 | 6,588

Collection

Kinase: IDG Consortium (Target... 7 | 125
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 6 | 499
abnormal skin coloration 3 | 25
abnormal skin morphology 3 | 50
decreased mean corpuscular vol... 3 | 79
embryonic lethality prior to o... 3 | 239
female infertility 3 | 60
impaired pupillary reflex 3 | 26
small testis 3 | 58
abnormal coat-hair pigmentatio... 2 | 64
abnormal testis morphology 2 | 43
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased mean corpuscular hem... 2 | 50
decreased vertical activity 2 | 208
edema 2 | 59
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
male infertility 2 | 123
short tibia 2 | 97
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coping response 1 | 1
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal digestive system phys... 1 | 1
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal urination 1 | 1
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged pancreas 1 | 2
enlarged spleen 1 | 41
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating magnesiu... 1 | 10
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 103 | 11,493
ovarian cancer 89 | 8,520
osteosarcoma 85 | 7,950
psoriasis 68 | 6,694
glioblastoma 65 | 5,792
medulloblastoma, large-cell 59 | 6,241
ependymoma 51 | 4,679
group 3 medulloblastoma 48 | 4,104
invasive ductal carcinoma 47 | 2,951
Breast cancer 46 | 3,578
lung cancer 46 | 4,740
adult high grade glioma 43 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,989
ulcerative colitis 42 | 1,819
atypical teratoid / rhabdoid tumor 40 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
Astrocytoma, Pilocytic 39 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
lung carcinoma 38 | 2,843
malignant mesothelioma 38 | 3,232
Cancer 37 | 2,499
oligodendroglioma 37 | 2,850
interstitial cystitis 36 | 2,312
non-small cell lung cancer 35 | 2,890
pancreatic cancer 35 | 2,398
Kidney cancer 30 | 2,613
tuberculosis 30 | 2,010
astrocytic glioma 28 | 2,597
breast carcinoma 28 | 1,638
ductal carcinoma in situ 28 | 1,745
lung adenocarcinoma 28 | 2,716
subependymal giant cell astrocytoma 28 | 2,287
cystic fibrosis 27 | 1,696
adrenocortical carcinoma 26 | 1,428
primitive neuroectodermal tumor 24 | 3,035
group 4 medulloblastoma 23 | 1,855
Schizophrenia 21 | 1,160
colon cancer 21 | 1,478
pituitary cancer 21 | 1,972
diabetes mellitus 20 | 1,728
acute quadriplegic myopathy 19 | 1,158
juvenile dermatomyositis 19 | 1,187
Pick disease 18 | 1,894
primary pancreatic ductal adenocarcinoma 18 | 1,109
Duchenne muscular dystrophy 17 | 601
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Liver Cirrhosis, Experimental 16 | 769
Waldenstrons macroglobulinemia 16 | 765
cutaneous lupus erythematosus 16 | 1,057
astrocytoma 15 | 1,146
spina bifida 15 | 1,074
Down syndrome 14 | 499
gastric carcinoma 14 | 807
Alzheimer's disease 13 | 658
Atopic dermatitis 13 | 952
Rheumatoid arthritis 13 | 1,191
dermatomyositis 13 | 966
fibroadenoma 13 | 559
Autosomal recessive predisposition 12 | 1,442
Bipolar Disorder 12 | 666
Multiple myeloma 12 | 1,332
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
mucosa-associated lymphoid tissue lymphoma 12 | 484
primary Sjogren syndrome 12 | 735
Asthma 11 | 385
Hypertension 11 | 396
Kidney disease 11 | 430
nasopharyngeal carcinoma 11 | 1,058
Breast Neoplasms 10 | 445
Myocardial Ischemia 10 | 169
esophageal adenocarcinoma 10 | 737
Endometriosis 9 | 540
Mammary Neoplasms 9 | 425
Renal Cell Carcinoma 9 | 214
gastric cancer 9 | 459
pancreatic carcinoma 9 | 562
Amyotrophic lateral sclerosis 8 | 451
Atherosclerosis 8 | 291
Cerebrovascular disease 8 | 238
Chronic Lymphocytic Leukemia 8 | 262
Coronary artery disease 8 | 268
Liver cancer 8 | 604
Neoplasm Invasiveness 8 | 161
Prostatic Neoplasms 8 | 495
active Crohn's disease 8 | 922
acute myeloid leukemia 8 | 783
aldosterone-producing adenoma 8 | 665
Anemia 7 | 365
Brain Ischemia 7 | 110
Heart disease 7 | 306
Hypereosinophilic syndrome 7 | 71
Hypersensitivity 7 | 63
Hypertensive disease 7 | 292
Intellectual disability 7 | 1,016
Lung disease 7 | 142
Major Depressive Disorder 7 | 301
Mesothelioma, Malignant 7 | 105
Pneumonia 7 | 174
Polycystic ovary syndrome 7 | 360
hepatocellular carcinoma 7 | 547

Tissue

Endocrine System 137 | 18,159
Blood and immune system 136 | 16,909
Skin and soft tissues 136 | 17,230
Digestive Tract 135 | 17,369
Liver and Pancreas 135 | 16,750
Male tissues 135 | 17,142
Female tissues 134 | 17,400
Urinary Tract 134 | 16,678
Nervous System 132 | 16,725
Respiratory system 132 | 16,393
Cardiovascular System 128 | 15,192

Target Family

Non-IDG 91 | 12,091
Kinase 24 | 634
Enzyme 15 | 4,145
Epigenetic 3 | 242
Transporter 3 | 473
GPCR 1 | 408

GO Process

regulation of cell shape 137 | 137
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Serine/threonine-protein kinase VRK2 VRK2 Tbio Kinase -1.28897 20.5 123
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.99923 14.5 99
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Tau-tubulin kinase 1 TTBK1 Tbio Kinase -1.11715 13.1 161
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583