Development Level

Tbio 49 | 11,445
Tchem 12 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 4 | 298
abnormal coat-hair pigmentatio... 3 | 64
enlarged heart 3 | 210
increased heart weight 3 | 62
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating triglyce... 2 | 79
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal rib morphology 1 | 10
abnormal skin coloration 1 | 25
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased granulocyte number 1 | 6
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
irregularly shaped pupil 1 | 7
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 48 | 11,493
ovarian cancer 40 | 8,520
glioblastoma 33 | 5,792
medulloblastoma, large-cell 31 | 6,241
ependymoma 30 | 4,679
osteosarcoma 30 | 7,950
psoriasis 28 | 6,694
atypical teratoid / rhabdoid tumor 27 | 5,112
lung cancer 27 | 4,740
Breast cancer 25 | 3,578
pancreatic cancer 24 | 2,398
Kidney cancer 22 | 2,613
Astrocytoma, Pilocytic 20 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
lung carcinoma 20 | 2,843
non-small cell lung cancer 19 | 2,890
group 3 medulloblastoma 18 | 4,104
Cancer 17 | 2,499
adult high grade glioma 17 | 3,801
oligodendroglioma 17 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
malignant mesothelioma 16 | 3,232
astrocytic glioma 15 | 2,597
interstitial cystitis 15 | 2,312
lung adenocarcinoma 15 | 2,716
Schizophrenia 14 | 1,160
cystic fibrosis 14 | 1,696
ductal carcinoma in situ 14 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
invasive ductal carcinoma 14 | 2,951
Pick disease 13 | 1,894
colon cancer 13 | 1,478
subependymal giant cell astrocytoma 13 | 2,287
ulcerative colitis 13 | 1,819
breast carcinoma 12 | 1,638
primary pancreatic ductal adenocarcinoma 12 | 1,109
diabetes mellitus 11 | 1,728
primitive neuroectodermal tumor 11 | 3,035
gastric carcinoma 10 | 807
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
progressive supranuclear palsy 10 | 676
Alzheimer's disease 9 | 658
Bipolar Disorder 9 | 666
adrenocortical carcinoma 9 | 1,428
juvenile dermatomyositis 9 | 1,187
tuberculosis 9 | 2,010
Autosomal recessive predisposition 8 | 1,442
Melanoma 8 | 711
acute quadriplegic myopathy 8 | 1,158
group 4 medulloblastoma 8 | 1,855
pituitary cancer 8 | 1,972
Duchenne muscular dystrophy 7 | 601
Heart disease 7 | 306
Kidney disease 7 | 430
Liver cancer 7 | 604
Myopia 7 | 176
Neurodegenerative disease 7 | 414
active ulcerative colitis 7 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
primary Sjogren syndrome 7 | 735
Endometrial cancer 6 | 311
Lung Neoplasms 6 | 232
Mammary Neoplasms 6 | 425
Rheumatoid arthritis 6 | 1,191
Skin cancer 6 | 469
astrocytoma 6 | 1,146
dermatomyositis 6 | 966
pediatric high grade glioma 6 | 1,064
Amyotrophic lateral sclerosis 5 | 451
Blepharoptosis 5 | 231
Breast Neoplasms 5 | 445
Cognitive delay 5 | 608
Deafness 5 | 198
Down syndrome 5 | 499
Epilepsy 5 | 792
Global developmental delay 5 | 608
Hypertension 5 | 396
Hypoplastic mandible condyle 5 | 275
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Mandibular hypoplasia 5 | 275
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Multiple myeloma 5 | 1,332
Obesity 5 | 678
Seizures 5 | 596
Strabismus 5 | 270
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
gastric cancer 5 | 459
medulloblastoma 5 | 720
sonic hedgehog group medulloblastoma 5 | 467
spina bifida 5 | 1,074
Depressive disorder 4 | 409
Glaucoma 4 | 239
Waldenstrons macroglobulinemia 4 | 765
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058

Tissue

Skin and soft tissues 64 | 17,230
Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Nervous System 63 | 16,725
Urinary Tract 63 | 16,678
Liver and Pancreas 62 | 16,750
Respiratory system 60 | 16,393
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 43 | 12,091
Kinase 9 | 634
Enzyme 8 | 4,145
Transcription Factor 4 | 1,400
GPCR 1 | 408

GO Process

regulation of cell migration 65 | 65
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein BEX4 BEX4 Tbio Non-IDG -0.42070 1.71 90
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
LIM domain-binding protein 2 LDB2 Tbio Non-IDG -1.58628 38.6 191
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 ENPP2 Tchem Enzyme -2.62921 463.2 377
Roundabout homolog 4 ROBO4 Tbio Non-IDG -2.01187 103.9 250
Somatostatin SST Tbio Non-IDG -4.14886 13572.0 397
Misshapen-like kinase 1 MINK1 Tchem Kinase -2.10181 122.3 178