Development Level

Tbio 49 | 10,625
Tchem 18 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased lean body mass 2 | 195
increased mean corpuscular vol... 2 | 91
tremors 2 | 34
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 2
abnormal vocalization 1 | 21
decreased KLRG1-positive NK ce... 1 | 9
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
hypoactivity 1 | 89
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating total pr... 1 | 20
increased effector memory CD4-... 1 | 15
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
small testis 1 | 37
straub tail 1 | 26

Disease

ovarian cancer 39 | 8,484
medulloblastoma, large-cell 37 | 6,234
psoriasis 34 | 6,685
osteosarcoma 33 | 7,933
glioblastoma 29 | 5,572
non-small cell lung cancer 29 | 2,798
Cancer 28 | 2,346
atypical teratoid / rhabdoid tumor 27 | 4,369
lung cancer 27 | 4,466
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,988
lung adenocarcinoma 25 | 2,713
malignant mesothelioma 25 | 3,162
pancreatic cancer 22 | 2,300
pituitary cancer 21 | 1,972
Breast cancer 20 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
adrenocortical carcinoma 19 | 1,427
ulcerative colitis 19 | 2,087
invasive ductal carcinoma 18 | 2,950
pilocytic astrocytoma 18 | 3,086
primitive neuroectodermal tumor 18 | 3,031
breast carcinoma 17 | 1,614
cystic fibrosis 17 | 1,665
interstitial cystitis 17 | 2,299
lung carcinoma 16 | 2,844
oligodendroglioma 16 | 2,849
colon cancer 15 | 1,475
ductal carcinoma in situ 15 | 1,745
primary pancreatic ductal adenocarcinoma 15 | 1,271
diabetes mellitus 14 | 1,663
ependymoma 14 | 2,514
pediatric high grade glioma 14 | 2,712
Carcinoma 12 | 2,147
adult high grade glioma 12 | 2,148
group 3 medulloblastoma 12 | 2,254
sonic hedgehog group medulloblastoma 12 | 1,482
subependymal giant cell astrocytoma 12 | 2,287
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Rheumatoid Arthritis 9 | 1,160
astrocytic glioma 9 | 2,241
gastric carcinoma 9 | 832
group 4 medulloblastoma 9 | 1,875
posterior fossa group A ependymoma 9 | 1,511
Atopic dermatitis 8 | 944
Duchenne muscular dystrophy 8 | 602
Pick disease 8 | 1,893
fibroadenoma 8 | 557
juvenile dermatomyositis 8 | 1,189
Down syndrome 7 | 548
acute quadriplegic myopathy 7 | 1,157
posterior fossa group B ependymoma 7 | 1,530
primary Sjogren syndrome 7 | 789
Endometriosis 6 | 535
Hypertensive disease 6 | 193
Obesity 6 | 616
Prostatic Neoplasms 6 | 471
dermatomyositis 6 | 933
nephrosclerosis 6 | 329
urothelial carcinoma 6 | 318
Acquired metabolic disease 5 | 267
Adenocarcinoma 5 | 115
Amyotrophic Lateral Sclerosis 5 | 431
Becker muscular dystrophy 5 | 187
Heart disease 5 | 279
IGA Glomerulonephritis 5 | 454
Lung Neoplasms 5 | 171
Mammary Neoplasms 5 | 410
active Crohn's disease 5 | 918
aldosterone-producing adenoma 5 | 664
astrocytoma 5 | 1,493
cutaneous lupus erythematosus 5 | 1,056
esophageal adenocarcinoma 5 | 737
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
non primary Sjogren syndrome sicca 5 | 840
spina bifida 5 | 1,064
tuberculosis 5 | 1,557
Heart failure 4 | 80
Hypertension 4 | 287
Kidney disease 4 | 396
Spontaneous abortion 4 | 108
limb girdle muscular dystrophy 2I 4 | 56
non-small cell lung carcinoma 4 | 413
sarcoidosis 4 | 358
Atherosclerosis 3 | 275
Bladder Neoplasm 3 | 109
Contact Dermatitis 3 | 80
Essential Hypertension 3 | 82
Liver carcinoma 3 | 217
Multiple myeloma 3 | 1,327
Myocardial Ischemia 3 | 169
Pancreatic Neoplasm 3 | 79
Stomach Neoplasms 3 | 282
Waldenstrons macroglobulinemia 3 | 765
chronic rhinosinusitis 3 | 512
inflammatory breast cancer 3 | 404
mucosa-associated lymphoid tissue lymphoma 3 | 480
tuberculosis and treatment for 6 months 3 | 686

Tissue

Cardiovascular System 71 | 17,958
Digestive Tract 71 | 18,473
Endocrine System 71 | 18,512
Female tissues 71 | 18,647
Liver and Pancreas 71 | 18,136
Nervous System 71 | 18,561
Urinary Tract 71 | 18,444
Blood and immune system 70 | 17,995
Male tissues 70 | 17,969
Respiratory system 70 | 17,484
Skin and soft tissues 70 | 18,115

Target Family

Non-IDG 46 | 11,971
Enzyme 10 | 4,146
Kinase 10 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 406
Ion Channel 1 | 341

GO Process

regulation of cell growth 71 | 71
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Transmembrane channel-like protein 8 TMC8 Tbio Ion Channel -1.45295 32.2 147
Cyclic AMP-responsive element-binding protein 3 CREB3 Tbio Transcription Factor -1.61736 42.0 159
Rho guanine nucleotide exchange factor 11 ARHGEF11 Tbio Non-IDG -1.54485 39.7 163
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.21530 0.00000 460
Calsyntenin-1 CLSTN1 Tbio Non-IDG -1.08669 14.3 106
Testican-1 SPOCK1 Tbio Non-IDG -1.93737 93.7 75
Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 Tbio Non-IDG -2.42637 343.3 423
Insulin-like growth factor-binding protein 6 IGFBP6 Tchem Non-IDG -2.03210 118.4 201
Insulin-like growth factor-binding protein 5 IGFBP5 Tchem Non-IDG -2.50193 346.6 226