Development Level

Tbio 19 | 11,445
Tchem 7 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
improved glucose tolerance 2 | 79
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased body length 1 | 101
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased body length 1 | 32
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
small testis 1 | 58

Disease

ovarian cancer 19 | 8,520
Carcinoma 17 | 11,493
psoriasis 15 | 6,694
Cancer 14 | 2,499
Breast cancer 12 | 3,578
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
lung adenocarcinoma 10 | 2,716
medulloblastoma, large-cell 10 | 6,241
non-small cell lung cancer 10 | 2,890
osteosarcoma 9 | 7,950
ductal carcinoma in situ 8 | 1,745
lung cancer 8 | 4,740
Orbital separation excessive 7 | 244
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
adrenocortical carcinoma 6 | 1,428
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
tuberculosis 6 | 2,010
Concave bridge of nose 5 | 195
Craniofacial Abnormalities 5 | 151
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Hypoplastic mandible condyle 5 | 275
Hypotrophic malar bone 5 | 129
Malar flattening 5 | 129
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
adult high grade glioma 5 | 3,801
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Blepharoptosis 4 | 231
Breast Neoplasms 4 | 445
Broad flat nasal bridge 4 | 236
Byzanthine arch palate 4 | 194
Cleft Palate 4 | 271
Decreased projection of midface 4 | 105
Downward slant of palpebral fissure 4 | 158
Epilepsy 4 | 792
Hypotrophic midface 4 | 105
Kidney cancer 4 | 2,613
Low set ears 4 | 181
Lung Neoplasms 4 | 232
Mammary Neoplasms 4 | 425
Midface retrusion 4 | 105
Nasal bridge wide 4 | 236
Short stature 4 | 531
Small midface 4 | 105
Stomach Neoplasms 4 | 300
Strabismus 4 | 270
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
malignant mesothelioma 4 | 3,232
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired metabolic disease 3 | 336
Astrocytoma, Pilocytic 3 | 3,081
Class III malocclusion 3 | 78
Cleft Lip 3 | 141
Cognitive delay 3 | 608
Cryptorchidism 3 | 296
Fetal Growth Retardation 3 | 189
Global developmental delay 3 | 608
Hypertrophy of lower jaw 3 | 78
Increased size of mandible 3 | 78
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Kidney disease 3 | 430
Low-set, posteriorly rotated ears 3 | 110
Mandibular hyperplasia 3 | 78
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Obesity 3 | 678
Schizophrenia 3 | 1,160
Seizures 3 | 596
Short neck 3 | 140
Uranostaphyloschisis 3 | 167
Wide spaced nipples 3 | 46
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
fibroadenoma 3 | 559
juvenile dermatomyositis 3 | 1,187
mandibular excess (physical finding) 3 | 78
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
ulcerative colitis 3 | 1,819

Tissue

Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Urinary Tract 27 | 16,678
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Cardiovascular System 24 | 15,192

Target Family

Transcription Factor 11 | 1,400
Non-IDG 8 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634

GO Process

regulation of cell differentia... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor-like 5 protein TCFL5 Tbio Transcription Factor -2.62447 404.7 161
Polypyrimidine tract-binding protein 3 PTBP3 Tbio Non-IDG -1.42815 24.5 127
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Testican-2 SPOCK2 Tbio Non-IDG -0.87419 6.75 57
Homeobox protein NANOG NANOG Tbio Transcription Factor -2.94914 1130.5 958
Tyrosine-protein kinase Fes/Fps FES Tchem Kinase -3.05038 1109.2 314