Development Level

Tbio 61 | 10,625
Tchem 22 | 1,890
Tdark 7 | 7,003
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 5 | 187
abnormal behavior 3 | 226
increased circulating alkaline... 3 | 119
abnormal bone mineralization 2 | 55
abnormal coat/hair pigmentatio... 2 | 54
abnormal lens morphology 2 | 73
decreased basophil cell number 2 | 11
decreased lean body mass 2 | 195
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal femur morphology 1 | 14
abnormal locomotor activation 1 | 26
abnormal maxilla morphology 1 | 16
abnormal retina morphology 1 | 100
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
decreased KLRG1-positive NK ce... 1 | 9
decreased body weight 1 | 174
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased erythrocyte cell num... 1 | 43
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased vertical activity 1 | 22
female infertility 1 | 34
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating choleste... 1 | 53
increased effector memory CD4-... 1 | 15
increased fasted circulating g... 1 | 68
increased kidney weight 1 | 4
increased leukocyte cell numbe... 1 | 37
increased monocyte cell number 1 | 27
increased startle reflex 1 | 38
limb grasping 1 | 35
male infertility 1 | 62
prolonged RR interval 1 | 2
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 60 | 8,484
osteosarcoma 48 | 7,933
Cancer 47 | 2,346
medulloblastoma, large-cell 43 | 6,234
psoriasis 42 | 6,685
glioblastoma 40 | 5,572
lung cancer 33 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
primitive neuroectodermal tumor 29 | 3,031
non-small cell lung cancer 27 | 2,798
atypical teratoid / rhabdoid tumor 26 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
lung adenocarcinoma 25 | 2,713
group 3 medulloblastoma 22 | 2,254
invasive ductal carcinoma 22 | 2,950
malignant mesothelioma 22 | 3,162
pediatric high grade glioma 22 | 2,712
adrenocortical carcinoma 21 | 1,427
Breast cancer 20 | 3,094
pancreatic cancer 19 | 2,300
subependymal giant cell astrocytoma 18 | 2,287
Multiple myeloma 17 | 1,327
ductal carcinoma in situ 16 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
Waldenstrons macroglobulinemia 15 | 765
astrocytoma 15 | 1,493
breast carcinoma 15 | 1,614
interstitial cystitis 15 | 2,299
juvenile dermatomyositis 15 | 1,189
lung carcinoma 15 | 2,844
pilocytic astrocytoma 15 | 3,086
dermatomyositis 14 | 933
pituitary cancer 14 | 1,972
posterior fossa group A ependymoma 14 | 1,511
Carcinoma 13 | 2,147
astrocytic glioma 13 | 2,241
diabetes mellitus 13 | 1,663
oligodendroglioma 13 | 2,849
sonic hedgehog group medulloblastoma 13 | 1,482
atypical teratoid/rhabdoid tumor 12 | 1,095
ependymoma 12 | 2,514
nasopharyngeal carcinoma 12 | 1,056
tuberculosis 12 | 1,557
Endometriosis 11 | 535
acute myeloid leukemia 11 | 780
Atopic dermatitis 10 | 944
Mammary Neoplasms 10 | 410
Rheumatoid Arthritis 10 | 1,160
adult high grade glioma 10 | 2,148
colon cancer 10 | 1,475
primary pancreatic ductal adenocarcinoma 10 | 1,271
Pick disease 9 | 1,893
cystic fibrosis 9 | 1,665
group 4 medulloblastoma 9 | 1,875
inflammatory breast cancer 8 | 404
medulloblastoma 8 | 1,524
ulcerative colitis 8 | 2,087
Colonic Neoplasms 7 | 126
Down syndrome 7 | 548
IGA Glomerulonephritis 7 | 454
Liver carcinoma 7 | 217
Multiple Sclerosis 7 | 498
gastric cancer 7 | 430
primary Sjogren syndrome 7 | 789
Amyotrophic Lateral Sclerosis 6 | 431
Arthritis 6 | 248
Squamous cell carcinoma 6 | 94
Stomach Neoplasms 6 | 282
Vascular disease 6 | 281
acute quadriplegic myopathy 6 | 1,157
aldosterone-producing adenoma 6 | 664
esophageal adenocarcinoma 6 | 737
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Alzheimer's disease 5 | 644
Crohn's disease 5 | 304
Kidney disease 5 | 396
Lung Neoplasms 5 | 171
Obesity 5 | 616
Polycystic Ovary Syndrome 5 | 332
chronic rhinosinusitis 5 | 512
cutaneous lupus erythematosus 5 | 1,056
ovarian neoplasm 5 | 97
posterior fossa group B ependymoma 5 | 1,530
tuberculosis and treatment for 6 months 5 | 686
Heart disease 4 | 279
Intellectual disability 4 | 573
Leukemia 4 | 88
Myocardial Ischemia 4 | 169
Parkinson's disease 4 | 364
Reperfusion Injury 4 | 84
Status Epilepticus 4 | 85
active Crohn's disease 4 | 918
facioscapulohumeral dystrophy 4 | 286
nephrosclerosis 4 | 329
non primary Sjogren syndrome sicca 4 | 840
non-small cell lung carcinoma 4 | 413
pancreatic carcinoma 4 | 567
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
tuberculosis and treatment for 3 months 4 | 327

Tissue

Blood and immune system 93 | 17,995
Cardiovascular System 93 | 17,958
Endocrine System 93 | 18,512
Female tissues 93 | 18,647
Liver and Pancreas 93 | 18,136
Male tissues 93 | 17,969
Nervous System 93 | 18,561
Urinary Tract 93 | 18,444
Digestive Tract 92 | 18,473
Skin and soft tissues 92 | 18,115
Respiratory system 91 | 17,484

Target Family

Non-IDG 53 | 11,971
Transcription Factor 14 | 1,400
Enzyme 12 | 4,146
Kinase 7 | 634
Epigenetic 4 | 242
TF/Epigenetic 2 | 38
Ion Channel 1 | 341

GO Process

regulation of cell cycle 93 | 93
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Period circadian protein homolog 2 PER2 Tchem Non-IDG -2.62596 424.2 213
Nanos homolog 3 NANOS3 Tbio Non-IDG -1.55057 39.4 76
Breakpoint cluster region protein BCR Tclin Non-IDG -2.96152 896.0 391
Protein lin-9 homolog LIN9 Tbio Non-IDG -1.88736 79.3 89
TMF-regulated nuclear protein 1 TRNP1 Tdark Non-IDG -0.30103 2.27 2
Phosphatase and actin regulator 4 PHACTR4 Tbio Enzyme -0.74255 6.19 78
Tuberin TSC2 Tbio Non-IDG -2.94615 933.5 1483