Development Level

Tbio 25 | 11,445
Tchem 8 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
preweaning lethality, incomple... 2 | 499
abnormal coat-hair pigmentatio... 1 | 64
abnormal eating behavior 1 | 1
abnormal forced expiratory flo... 1 | 1
abnormal skin morphology 1 | 50
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased tidal volume 1 | 1
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 35 | 11,493
ovarian cancer 29 | 8,520
Cancer 20 | 2,499
glioblastoma 20 | 5,792
medulloblastoma, large-cell 20 | 6,241
osteosarcoma 20 | 7,950
atypical teratoid / rhabdoid tumor 18 | 5,112
psoriasis 18 | 6,694
Breast cancer 17 | 3,578
lung cancer 17 | 4,740
Kidney cancer 16 | 2,613
ependymoma 15 | 4,679
adult high grade glioma 14 | 3,801
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
pancreatic cancer 13 | 2,398
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
Astrocytoma, Pilocytic 11 | 3,081
lung adenocarcinoma 11 | 2,716
astrocytic glioma 10 | 2,597
oligodendroglioma 10 | 2,850
primitive neuroectodermal tumor 10 | 3,035
tuberculosis 10 | 2,010
colon cancer 9 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
cystic fibrosis 8 | 1,696
subependymal giant cell astrocytoma 8 | 2,287
Rheumatoid arthritis 7 | 1,191
ductal carcinoma in situ 7 | 1,745
non-small cell lung cancer 7 | 2,890
ulcerative colitis 7 | 1,819
Hypertension 6 | 396
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
primary pancreatic ductal adenocarcinoma 6 | 1,109
Epilepsy 5 | 792
Heart disease 5 | 306
Seizures 5 | 596
breast carcinoma 5 | 1,638
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Colorectal Neoplasms 4 | 243
Down syndrome 4 | 499
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Muscle hypotonia 4 | 571
Osteoarthritis 4 | 184
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
head and neck cancer 4 | 271
nasopharyngeal carcinoma 4 | 1,058
periodontitis 4 | 293
spina bifida 4 | 1,074
Alcoholic Intoxication, Chronic 3 | 289
Asthma 3 | 385
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Diarrhea 3 | 253
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Gastroesophageal reflux disease 3 | 110
Glaucoma 3 | 239
Kidney disease 3 | 430
Low intelligence 3 | 645
Mental deficiency 3 | 645
Multiple Sclerosis 3 | 540
Myopia 3 | 176
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Prenatal onset 3 | 139
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
hepatocellular carcinoma 3 | 547
hereditary spastic paraplegia 3 | 318
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735

Tissue

Endocrine System 39 | 18,159
Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Liver and Pancreas 38 | 16,750
Nervous System 38 | 16,725
Skin and soft tissues 38 | 17,230
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Respiratory system 37 | 16,393
Urinary Tract 37 | 16,678
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 19 | 12,091
Kinase 10 | 634
Enzyme 7 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

regulation of cell adhesion 39 | 39
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
LIM domain only protein 7 LMO7 Tbio Non-IDG -1.24771 19.7 80
Abelson tyrosine-protein kinase 2 ABL2 Tchem Kinase -1.86293 71.2 358
cAMP-dependent protein kinase catalytic subunit PRKX PRKX Tchem Kinase -1.17196 28.7 183
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Cytohesin-1 CYTH1 Tbio Non-IDG -2.10475 140.2 194