Development Level

Tbio 2 | 11,445

IMPC Phenotype

abnormal sensory capabilities-... 1 | 8
decreased circulating alkaline... 1 | 46
decreased eosinophil cell numb... 1 | 24
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 2 | 11,493
Gaucher disease type 1 2 | 180
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal dermatoglyphic pattern 1 | 24
Abnormal visual evoked potential 1 | 26
Abnormality of nail of toe 1 | 11
Abnormality of position of teeth 1 | 8
Abnormality of retinal pigmentation 1 | 111
Acrokeratosis 1 | 2
Acrokeratosis Verruciformis of Hopf 1 | 1
Acrokeratosis verruciformis 1 | 1
Agyria 1 | 15
Anal mucosal leukoplakia 1 | 2
Autosomal dominant nonsyndromic deafness 25 1 | 6
Blepharoptosis 1 | 231
Blindness, Cortical 1 | 24
Brachycephaly 1 | 88
Broad cranium shape 1 | 88
Brody myopathy 1 | 3
Cardiomegaly 1 | 116
Clitoral hypoplasia 1 | 11
Congenital Bilateral Cataracts 1 | 50
Corneal ectasia 1 | 11
Cortical visual impairment 1 | 24
Darier Disease 1 | 1
Darier-White Disease 1 | 1
Decreased projection of midface 1 | 105
Degenerative brain disorder 1 | 100
Delayed Puberty 1 | 97
Diabetes Mellitus, Experimental 1 | 108
Diabetic Cardiomyopathies 1 | 10
Dowling-Degos disease 1 | 7
Eczema herpeticum 1 | 7
Enophthalmos 1 | 75
Epidermolytic hyperkeratosis 1 | 14
Everted lower lip vermilion 1 | 54
Fissured tongue 1 | 25
Frey syndrome 1 | 4
Generalized hirsutism 1 | 36
Glomangiomatosis 1 | 4
Hair shaft abnormalities 1 | 30
Heart Diseases 1 | 43
Heart failure 1 | 162
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Hyperpigmented macules 1 | 42
Hypertrophy of parotid gland 1 | 1
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplasia or absence of the corpus callosum 1 | 23
Hypoplastic labia minora 1 | 10
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Joint stiffness 1 | 84
Keratoconus 1 | 113
Keratosis follicularis 1 | 3
Kyphoscoliosis deformity of spine 1 | 60
Kyphosis deformity of spine 1 | 114
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Lichen nitidus 1 | 3
Little's Disease 1 | 14
Lordosis 1 | 54
Low posterior hairline 1 | 52
Malar flattening 1 | 129
Martsolf syndrome 1 | 2
Microphthalmia 1 | 76
Midface retrusion 1 | 105
Mild Mental Retardation 1 | 70
Misalignment of teeth 1 | 8
Myocardial Infarction 1 | 151
Myocardial Reperfusion Injury 1 | 37
Myocardial stunning 1 | 8
Osteoporosis 1 | 363
Paget's disease of bone 1 | 36
Palmar pit 1 | 4
Palmoplantar keratosis 1 | 74
Plantar pits 1 | 4
Precociously senile appearance 1 | 18
Protruding lower lip 1 | 54
Pruritus 1 | 58
Retinal pigment epithelial abnormality 1 | 111
Ridged nails 1 | 14
Short philtrum 1 | 53
Small midface 1 | 105
Spastic diplegia 1 | 5
Subungual hyperkeratotic fragments 1 | 1
Sunken eyes 1 | 63
Supratentorial atrophy 1 | 94
Tinea manuum 1 | 4
Ventricular Dysfunction, Left 1 | 22
Warburg Sjo Fledelius syndrome 1 | 4
Wide skull shape 1 | 88
hair abnormalities (non-specific) 1 | 30
steroid-induced glaucoma 1 | 8

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Transporter 1 | 473

GO Process

regulation of calcium ion-depe... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Rab3 GTPase-activating protein catalytic subunit RAB3GAP1 Tbio Enzyme -1.40654 26.0 104