Development Level

Tbio 26 | 10,625
Tchem 22 | 1,890
Tclin 15 | 602
Tdark 1 | 7,003

IMPC Phenotype

decreased body weight 3 | 174
abnormal gait 2 | 51
increased blood urea nitrogen ... 2 | 44
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal clavicle morphology 1 | 5
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal forced expiratory flo... 1 | 1
abnormal maxilla morphology 1 | 16
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased tidal volume 1 | 1
decreased total body fat amoun... 1 | 186
dilated heart left ventricle 1 | 10
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
straub tail 1 | 26

Disease

Hypertension 35 | 293
psoriasis 35 | 6,685
glioblastoma 29 | 5,572
lung cancer 29 | 4,473
ovarian cancer 29 | 8,491
diabetes mellitus 26 | 1,663
medulloblastoma, large-cell 25 | 6,234
Hypertensive disease 24 | 193
osteosarcoma 24 | 7,933
invasive ductal carcinoma 23 | 2,950
lung carcinoma 22 | 2,844
Cancer 21 | 2,346
Cerebrovascular disease 20 | 231
Heart disease 19 | 279
atypical teratoid / rhabdoid tumor 19 | 4,369
lung adenocarcinoma 19 | 2,714
Kidney disease 18 | 397
Obesity 18 | 616
ductal carcinoma in situ 18 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
breast carcinoma 17 | 1,614
interstitial cystitis 17 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
pancreatic cancer 17 | 2,300
pilocytic astrocytoma 17 | 3,086
Coronary artery disease 16 | 240
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
malignant mesothelioma 16 | 3,163
pediatric high grade glioma 16 | 2,712
Heart failure 15 | 80
colon cancer 15 | 1,475
primitive neuroectodermal tumor 15 | 3,031
ulcerative colitis 15 | 2,087
Atherosclerosis 14 | 275
Breast cancer 14 | 3,098
non-small cell lung cancer 14 | 2,798
oligodendroglioma 14 | 2,849
posterior fossa group A ependymoma 14 | 1,511
tuberculosis 14 | 1,563
Myocardial Infarction 13 | 126
Carcinoma 12 | 2,147
cystic fibrosis 12 | 1,670
adrenocortical carcinoma 11 | 1,427
adult high grade glioma 11 | 2,148
pituitary cancer 11 | 1,972
Alzheimer's disease 10 | 644
Asthma 10 | 349
Diabetes Mellitus, Non-Insulin-Dependent 10 | 161
Hyperglycemia 10 | 120
Lung disease 10 | 136
Osteoporosis 10 | 259
Pick disease 10 | 1,893
subependymal giant cell astrocytoma 10 | 2,287
Atopic dermatitis 9 | 944
Cardiomegaly 9 | 66
Diabetes Mellitus, Experimental 9 | 106
Hypotension 9 | 53
astrocytic glioma 9 | 2,241
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Adenoma 8 | 165
Arthritis 8 | 248
Hyperinsulinism 8 | 63
Inflammation 8 | 109
Kidney Diseases 8 | 86
Liver disease 8 | 219
Mammary Neoplasms 8 | 410
Metabolic syndrome X 8 | 155
Migraine 8 | 79
Myocardial Ischemia 8 | 169
Prostatic Neoplasms 8 | 471
Reperfusion Injury 8 | 84
astrocytoma 8 | 1,493
group 3 medulloblastoma 8 | 2,254
juvenile dermatomyositis 8 | 1,189
medulloblastoma 8 | 1,524
primary pancreatic ductal adenocarcinoma 8 | 1,271
Adenocarcinoma 7 | 115
Anemia 7 | 252
Colonic Neoplasms 7 | 126
Essential Hypertension 7 | 82
Fibrosis 7 | 40
Hypokalemia 7 | 40
Hypothyroidism 7 | 89
Ischemia 7 | 27
Pain agnosia 7 | 99
Parkinson's disease 7 | 364
Pulmonary hypertension 7 | 52
Seizures 7 | 95
Stomach Neoplasms 7 | 282
active Crohn's disease 7 | 918
esophageal adenocarcinoma 7 | 737
gastric carcinoma 7 | 832
nephrosclerosis 7 | 329
Atrial Fibrillation 6 | 110
Schizophrenia 6 | 503
acute quadriplegic myopathy 6 | 1,157
cutaneous lupus erythematosus 6 | 1,056
ependymoma 6 | 2,514
sonic hedgehog group medulloblastoma 6 | 1,482
urothelial carcinoma 6 | 318

Tissue

Digestive Tract 63 | 18,472
Endocrine System 63 | 18,511
Female tissues 63 | 18,646
Nervous System 63 | 18,560
Skin and soft tissues 63 | 18,114
Urinary Tract 63 | 18,443
Cardiovascular System 62 | 17,957
Liver and Pancreas 62 | 18,135
Respiratory system 62 | 17,483
Blood and immune system 61 | 17,994
Male tissues 61 | 17,968

Target Family

Non-IDG 25 | 11,969
Enzyme 21 | 4,146
GPCR 7 | 408
Kinase 5 | 634
Ion Channel 3 | 341
Transporter 2 | 473
Nuclear Receptor 1 | 48

GO Process

regulation of blood pressure 64 | 64
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyrotropin-releasing hormone-degrading ectoenzyme TRHDE Tdark Enzyme -1.61185 36.9 43
Aminopeptidase Q LVRN Tbio Enzyme -1.88550 67.2 12
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Angiotensinogen AGT Tchem Non-IDG -3.23867 1673.4 609
Endoplasmic reticulum aminopeptidase 2 ERAP2 Tchem Enzyme -1.68056 46.0 70
Melanocortin receptor 3 MC3R Tchem GPCR -2.63865 450.0 177
Endothelin-1 receptor EDNRA Tclin GPCR -2.84646 617.3 245
Natriuretic peptides A NPPA Tchem Non-IDG -3.23922 1719.8 429
Type-1 angiotensin II receptor-associated protein AGTRAP Tbio Non-IDG -1.48268 36.0 122
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.28015 198.7 195