Development Level

Tbio 10 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

enlarged heart 3 | 210
abnormal heart morphology 2 | 162
embryonic lethality prior to t... 2 | 278
abnormal kidney morphology 1 | 65
abnormal lymph node morphology 1 | 3
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
hydrometra 1 | 53
increased circulating insulin ... 1 | 3
increased lean body mass 1 | 172
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19
small superior vagus ganglion 1 | 74

Disease

Carcinoma 11 | 11,493
osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
Cancer 8 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Cerebrovascular disease 5 | 238
acute quadriplegic myopathy 5 | 1,158
glioblastoma 5 | 5,792
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Astrocytoma, Pilocytic 4 | 3,081
Cholestasis 4 | 155
Down syndrome 4 | 499
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 559
malignant mesothelioma 4 | 3,232
ulcerative colitis 4 | 1,819
Brain Edema 3 | 50
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Diabetic retinopathy 3 | 56
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
Rheumatoid arthritis 3 | 1,191
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
pituitary cancer 3 | 1,972
Alopecia 2 | 115
Amyotrophic lateral sclerosis 2 | 451
Angiostrongyliasis 2 | 4
Autosomal recessive predisposition 2 | 1,442
Cell Transformation, Neoplastic 2 | 97
Cleft Palate 2 | 271
Cleidocranial dysplasia 2 | 10
Diarrhea 2 | 253
Duchenne muscular dystrophy 2 | 601
Ecchymosis 2 | 66
Fatigue 2 | 182
Heart disease 2 | 306
Hypertensive disease 2 | 292
Increased tendency to bruise 2 | 66
Inflammatory bowel disease 2 | 151
Irritable bowel syndrome 2 | 60
Kidney disease 2 | 430
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Multiple Sclerosis 2 | 540
Muscle Weakness 2 | 170
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neoplastic Cell Transformation 2 | 89
Obesity 2 | 678
Paraplegia 2 | 74
Prostatic Neoplasms 2 | 495
Short stature 2 | 531
Small head 2 | 374
Splenomegaly 2 | 190
Telecanthus 2 | 62
Thyroid cancer, papillary 2 | 14
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
nephrosclerosis 2 | 333
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
primitive neuroectodermal tumor 2 | 3,035
pulmonary arterial hypertension 2 | 75
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318
Absence of a tooth 1 | 6
Anhedonia 1 | 27
Erythrokeratodermia variabilis 1 | 10
Fifth finger camptodactyly 1 | 3
Hyperkeratosis, generalized 1 | 14
Leukocytosis 1 | 17
Long nose 1 | 15
Macule 1 | 19
Short middle phalanx of the 5th finger 1 | 13

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Non-IDG 6 | 12,091
Transcription Factor 4 | 1,400
GPCR 2 | 408
Kinase 2 | 634

GO Process

regulation of bicellular tight... 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Claudin-5 CLDN5 Tbio Non-IDG -2.58968 349.4 300
G-protein coupled bile acid receptor 1 GPBAR1 Tchem GPCR -2.54070 373.2 189
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.20720 1368.9 292
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Unconventional myosin-Ic MYO1C Tbio Non-IDG -1.89688 82.6 117
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.28636 1782.9 566
Frizzled-5 FZD5 Tbio GPCR -1.54924 30.5 307
Core-binding factor subunit beta CBFB Tchem Transcription Factor -0.78193 5.82 291