Development Level

Tbio 23 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased bone mineral content 2 | 108
small superior vagus ganglion 2 | 74
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal vitreous body morphol... 1 | 10
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating glucose ... 1 | 24
increased circulating insulin ... 1 | 3
increased heart weight 1 | 62
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97

Disease

Carcinoma 22 | 11,493
ovarian cancer 20 | 8,520
osteosarcoma 12 | 7,950
Cancer 11 | 2,499
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
adult high grade glioma 10 | 3,801
lung cancer 10 | 4,740
psoriasis 10 | 6,694
atypical teratoid / rhabdoid tumor 9 | 5,112
Breast cancer 7 | 3,578
diabetes mellitus 7 | 1,728
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
Parkinson's disease 6 | 392
Schizophrenia 6 | 1,160
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
group 4 medulloblastoma 5 | 1,855
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Neurodegenerative disease 4 | 414
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Parkinsonian Disorders 3 | 56
Short stature 3 | 531
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Babinski Reflex 2 | 100
Bipolar Disorder 2 | 666
Brain disease 2 | 96
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Squamous Cell 2 | 110
Death in early childhood 2 | 82
Death in infancy 2 | 82
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Fatty liver disease 2 | 103
Frontal bossing 2 | 157
Hyperreflexia 2 | 209
Hypodontia 2 | 81
Immune system cancer 2 | 140
Insulin Resistance 2 | 72
Intellectual disability 2 | 1,016
Kidney Failure, Chronic 2 | 46
Lipid metabolism disorder 2 | 114
Liver carcinoma 2 | 240
MYELODYSPLASTIC SYNDROME 2 | 53
Muscle Spasticity 2 | 195
Myocardial Infarction 2 | 151
Nerve Degeneration 2 | 121
Obesity 2 | 678
Osteoporosis 2 | 363
PARKINSON DISEASE 19, JUVENILE-ONSET 2 | 10
Parkinson Disease 2 | 64
Rheumatoid arthritis 2 | 1,191
Squamous cell carcinoma 2 | 129
Young onset Parkinson disease 2 | 10
acute myeloid leukemia 2 | 783
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 6 months 2 | 409
Cervical Dystonia 1 | 26
Platyspondyly 1 | 56
Psychomotor Disorders 1 | 7
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Spasmodic torticollis 1 | 17
Spinocerebellar ataxia type 13 1 | 5
Supranuclear gaze palsy 1 | 6
Torticollis 1 | 18
relapsing-remitting multiple sclerosis 1 | 18

Tissue

Blood and immune system 29 | 16,909
Cardiovascular System 29 | 15,192
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678

Target Family

Non-IDG 13 | 12,091
Enzyme 5 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Transporter 2 | 473
GPCR 1 | 408

GO Process

regulation of autophagy of mit... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable palmitoyltransferase ZDHHC8 ZDHHC8 Tbio Enzyme -1.30633 19.3 116
Sterol regulatory element-binding protein 2 SREBF2 Tchem Transcription Factor -2.61148 361.0 205
Solute carrier family 17 member 9 SLC17A9 Tchem Transporter -1.56271 40.4 11
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
WD repeat-containing protein 75 WDR75 Tbio Non-IDG -0.42835 2.42 20
DNA-directed RNA polymerase III subunit RPC1 POLR3A Tbio Enzyme -2.25632 178.2 99
Dynamin-1-like protein DNM1L Tbio Non-IDG -2.65717 476.9 426
Histone acetyltransferase KAT2A KAT2A Tbio Epigenetic -2.46487 271.9 262
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BNIP3L Tbio Non-IDG -2.20837 153.7 355
Splicing factor U2AF 65 kDa subunit U2AF2 Tbio Non-IDG -2.14043 127.8 183