Development Level

Tbio 152 | 11,445
Tchem 73 | 1,598
Tdark 13 | 6,588
Tclin 12 | 613

Collection

Kinase: IDG Consortium (Target... 8 | 125
RFA-RM-18-021 8 | 328
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 9 | 499
abnormal gait 5 | 69
decreased body weight 5 | 161
embryonic lethality prior to t... 5 | 278
abnormal bone structure 4 | 187
decreased mean corpuscular vol... 4 | 79
decreased total body fat amoun... 4 | 207
hyperactivity 4 | 148
hypoactivity 4 | 132
decreased basophil cell number 3 | 16
decreased neutrophil cell numb... 3 | 42
decreased vertical activity 3 | 208
increased bone mineral density 3 | 72
increased lymphocyte cell numb... 3 | 32
increased neutrophil cell numb... 3 | 46
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal urinary bladder morph... 2 | 11
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating creatini... 2 | 39
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased threshold for audito... 2 | 26
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
female infertility 2 | 60
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
brachydactyly 1 | 19
cataract 1 | 92
decreased IgG1 level 1 | 8
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hydrometra 1 | 53
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased vertical activity 1 | 24
prenatal lethality 1 | 28
small kidney 1 | 16
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 167 | 11,493
ovarian cancer 137 | 8,520
osteosarcoma 133 | 7,950
lung cancer 109 | 4,740
psoriasis 105 | 6,694
Cancer 101 | 2,499
glioblastoma 93 | 5,792
medulloblastoma, large-cell 93 | 6,241
atypical teratoid / rhabdoid tumor 72 | 5,112
malignant mesothelioma 65 | 3,232
ependymoma 64 | 4,679
group 3 medulloblastoma 62 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,291
Breast cancer 60 | 3,578
pancreatic cancer 59 | 2,398
oligodendroglioma 56 | 2,850
Kidney cancer 53 | 2,613
adult high grade glioma 52 | 3,801
non-small cell lung cancer 52 | 2,890
lung carcinoma 51 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,955
tuberculosis 48 | 2,010
lung adenocarcinoma 46 | 2,716
Astrocytoma, Pilocytic 45 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
subependymal giant cell astrocytoma 43 | 2,287
invasive ductal carcinoma 42 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,962
primitive neuroectodermal tumor 39 | 3,035
breast carcinoma 38 | 1,638
diabetes mellitus 37 | 1,728
ulcerative colitis 37 | 1,819
astrocytic glioma 36 | 2,597
interstitial cystitis 36 | 2,312
pituitary cancer 36 | 1,972
ductal carcinoma in situ 34 | 1,745
cystic fibrosis 32 | 1,696
Multiple myeloma 31 | 1,332
group 4 medulloblastoma 31 | 1,855
Schizophrenia 30 | 1,160
Pick disease 29 | 1,894
Rheumatoid arthritis 29 | 1,191
Prostatic Neoplasms 27 | 495
astrocytoma 27 | 1,146
Autosomal recessive predisposition 25 | 1,442
Liver Cirrhosis, Experimental 25 | 769
juvenile dermatomyositis 25 | 1,187
Renal Cell Carcinoma 24 | 214
colon cancer 24 | 1,478
acute quadriplegic myopathy 23 | 1,158
primary pancreatic ductal adenocarcinoma 23 | 1,109
dermatomyositis 21 | 966
Alzheimer's disease 20 | 658
Breast Neoplasms 20 | 445
acute myeloid leukemia 20 | 783
pancreatic carcinoma 20 | 562
Atopic dermatitis 19 | 952
Vascular disease 19 | 319
Waldenstrons macroglobulinemia 19 | 765
adrenocortical carcinoma 19 | 1,428
gastric carcinoma 19 | 807
Mammary Neoplasms 18 | 425
cutaneous lupus erythematosus 18 | 1,057
pediatric high grade glioma 18 | 1,064
Melanoma 17 | 711
active Crohn's disease 17 | 922
esophageal adenocarcinoma 17 | 737
Kidney disease 16 | 430
Lung Neoplasms 16 | 232
nasopharyngeal carcinoma 16 | 1,058
non primary Sjogren syndrome sicca 16 | 891
Bipolar Disorder 15 | 666
Carcinoma, Hepatocellular 15 | 228
Liver carcinoma 15 | 240
Short stature 15 | 531
Stomach Neoplasms 15 | 300
gastric cancer 15 | 459
Anemia 14 | 365
Neurodegenerative disease 14 | 414
non-small cell lung carcinoma 14 | 317
spina bifida 14 | 1,074
Amyotrophic lateral sclerosis 13 | 451
Arthritis 13 | 290
Carcinoma, Renal Cell 13 | 124
Hypersensitivity reaction type II disease 13 | 253
Osteoporosis 13 | 363
Polycystic ovary syndrome 13 | 360
Blastic phase chronic myeloid leukemia 12 | 58
Chronic Myelocytic Leukemia Accelerated Phase 12 | 59
Depressive disorder 12 | 409
Down syndrome 12 | 499
Neoplasm Metastasis 12 | 168
Obesity 12 | 678
Splenomegaly 12 | 190
hepatocellular carcinoma 12 | 547
medulloblastoma 12 | 720
primary Sjogren syndrome 12 | 735
Chronic Lymphocytic Leukemia 11 | 262
Duchenne muscular dystrophy 11 | 601
Immune system cancer 11 | 140

Tissue

Endocrine System 244 | 18,159
Female tissues 241 | 17,400
Digestive Tract 239 | 17,369
Liver and Pancreas 238 | 16,750
Male tissues 237 | 17,142
Skin and soft tissues 237 | 17,230
Nervous System 235 | 16,725
Urinary Tract 234 | 16,678
Respiratory system 231 | 16,393
Blood and immune system 229 | 16,909
Cardiovascular System 228 | 15,192

Target Family

Non-IDG 133 | 12,091
Kinase 65 | 634
Enzyme 33 | 4,145
Transcription Factor 15 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

GO Process

regulation of apoptotic proces... 250 | 250
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
Ras association domain-containing protein 3 RASSF3 Tbio Non-IDG 0.00000 130
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Melanoma-associated antigen D1 MAGED1 Tbio Non-IDG -1.55131 46.3 245
Acidic leucine-rich nuclear phosphoprotein 32 family member E ANP32E Tbio Non-IDG -0.82034 5.60 97
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Caspase recruitment domain-containing protein 17 CARD17 Tbio Enzyme -0.13566 0.58 74
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121