Development Level

Tbio 19 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal head morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased erythrocyte cell num... 1 | 39
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17

Disease

ovarian cancer 23 | 8,520
Cancer 20 | 2,499
lung cancer 19 | 4,740
psoriasis 19 | 6,694
Breast cancer 17 | 3,578
Carcinoma 17 | 11,493
glioblastoma 16 | 5,792
ulcerative colitis 14 | 1,819
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
ependymoma 12 | 4,679
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
medulloblastoma, large-cell 12 | 6,241
non-small cell lung cancer 12 | 2,890
osteosarcoma 11 | 7,950
subependymal giant cell astrocytoma 11 | 2,287
Astrocytoma, Pilocytic 10 | 3,081
breast carcinoma 10 | 1,638
invasive ductal carcinoma 10 | 2,951
lung adenocarcinoma 10 | 2,716
pancreatic cancer 10 | 2,398
adult high grade glioma 9 | 3,801
cystic fibrosis 9 | 1,696
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pituitary cancer 9 | 1,972
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Liver Cirrhosis, Experimental 7 | 769
diabetes mellitus 7 | 1,728
oligodendroglioma 7 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Down syndrome 6 | 499
Prostatic Neoplasms 6 | 495
astrocytic glioma 6 | 2,597
fibroadenoma 6 | 559
Adenoma 5 | 167
Alzheimer's disease 5 | 658
Heart disease 5 | 306
Kidney disease 5 | 430
Liver disease 5 | 237
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
Vascular disease 5 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
group 3 medulloblastoma 5 | 4,104
juvenile dermatomyositis 5 | 1,187
Acute kidney injury 4 | 70
Arthritis 4 | 290
Coronary artery disease 4 | 268
Depressive disorder 4 | 409
Diabetes Mellitus, Experimental 4 | 108
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Disease Progression 4 | 136
Hypertensive disease 4 | 292
Inflammation 4 | 120
Kidney cancer 4 | 2,613
Liver Cirrhosis 4 | 181
Lung Neoplasms 4 | 232
Myocardial Ischemia 4 | 169
Neoplasm Metastasis 4 | 168
Reperfusion Injury 4 | 86
Stomach Neoplasms 4 | 300
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
dermatomyositis 4 | 966
periodontitis 4 | 293
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Anemia 3 | 365
Atherosclerosis 3 | 291
Carcinoma, Hepatocellular 3 | 228
Diabetes Mellitus, Type 2 3 | 142
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Hypersensitivity reaction type II disease 3 | 253
Hypertension 3 | 396
Liver carcinoma 3 | 240
Lung disease 3 | 142
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Parkinson's disease 3 | 392
Seizures 3 | 596
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
type II diabetes mellitus and post-ischemic heart failure 3 | 88

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
TF/Epigenetic 1 | 38

GO Process

regulation of angiogenesis 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Tetraspanin-12 TSPAN12 Tbio Non-IDG -1.33130 21.5 141
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Adhesion G protein-coupled receptor A2 ADGRA2 Tbio GPCR -1.45203 30.0 211
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 ENPP2 Tchem Enzyme -2.62921 463.2 377
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.74520 518.6 163
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Tumor necrosis factor receptor superfamily member 12A TNFRSF12A Tbio Non-IDG -2.13589 160.9 382
Protein C-ets-1 ETS1 Tbio Transcription Factor -2.89500 760.0 463