Development Level

Tbio 32 | 11,445
Tchem 6 | 1,598
Tclin 6 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
hyperactivity 3 | 148
mammalian phenotype 3 | 17
preweaning lethality, complete... 3 | 979
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal snout morphology 2 | 23
decreased blood urea nitrogen ... 2 | 51
decreased startle reflex 2 | 75
edema 2 | 59
increased circulating calcium ... 2 | 34
abnormal behavioral response t... 1 | 66
abnormal head morphology 1 | 10
abnormal limb bud morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
curly tail 1 | 1
decreased IgE level 1 | 6
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged adrenal glands 1 | 3
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
kinked tail 1 | 2
pallor 1 | 34
polycystic kidney 1 | 15
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 31 | 11,493
osteosarcoma 25 | 7,950
psoriasis 25 | 6,694
ovarian cancer 24 | 8,520
medulloblastoma, large-cell 22 | 6,241
ependymoma 20 | 4,679
Breast cancer 17 | 3,578
Cancer 17 | 2,499
glioblastoma 17 | 5,792
lung cancer 17 | 4,740
atypical teratoid / rhabdoid tumor 16 | 5,112
oligodendroglioma 16 | 2,850
astrocytic glioma 14 | 2,597
malignant mesothelioma 14 | 3,232
non-small cell lung cancer 14 | 2,890
Kidney cancer 13 | 2,613
pancreatic cancer 13 | 2,398
Astrocytoma, Pilocytic 12 | 3,081
invasive ductal carcinoma 12 | 2,951
adult high grade glioma 11 | 3,801
group 3 medulloblastoma 11 | 4,104
group 4 medulloblastoma 11 | 1,855
lung carcinoma 11 | 2,843
subependymal giant cell astrocytoma 11 | 2,287
colon cancer 9 | 1,478
cystic fibrosis 9 | 1,696
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung adenocarcinoma 8 | 2,716
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,035
spina bifida 8 | 1,074
Schizophrenia 7 | 1,160
ductal carcinoma in situ 7 | 1,745
tuberculosis 7 | 2,010
adrenocortical carcinoma 6 | 1,428
breast carcinoma 6 | 1,638
esophageal adenocarcinoma 6 | 737
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
ulcerative colitis 6 | 1,819
Hypertension 5 | 396
Liver Cirrhosis, Experimental 5 | 769
Pick disease 5 | 1,894
active Crohn's disease 5 | 922
acute quadriplegic myopathy 5 | 1,158
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
Atopic dermatitis 4 | 952
Blastic phase chronic myeloid leukemia 4 | 58
Chronic Lymphocytic Leukemia 4 | 262
Chronic Myelocytic Leukemia Accelerated Phase 4 | 59
Chronic phase chronic myeloid leukemia 4 | 45
Epilepsy 4 | 792
Liver cancer 4 | 604
Multiple myeloma 4 | 1,332
Parkinson's disease 4 | 392
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 4 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Seizures 4 | 596
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
juvenile dermatomyositis 4 | 1,187
mucosa-associated lymphoid tissue lymphoma 4 | 484
Alzheimer's disease 3 | 658
Anencephaly 3 | 26
Atherosclerosis 3 | 291
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Hydrolethalus syndrome 3 | 128
Impotence 3 | 42
Kidney disease 3 | 430
Mammary Neoplasms 3 | 425
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Thrombocytopenia 3 | 197
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
atypical teratoid/rhabdoid tumor 3 | 357
hereditary spastic paraplegia 3 | 318
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
Depressive disorder 2 | 409
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Glaucoma 2 | 239
Heart disease 2 | 306
Hepatomegaly 2 | 285
Hypereosinophilic syndrome 2 | 71
Major Depressive Disorder 2 | 301
Unipolar Depression 2 | 250
chronic rhinosinusitis 2 | 512
medulloblastoma 2 | 720
tuberculosis and treatment for 3 months 2 | 179

Tissue

Digestive Tract 46 | 17,369
Endocrine System 45 | 18,159
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909
Female tissues 44 | 17,400
Skin and soft tissues 44 | 17,230
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Respiratory system 43 | 16,393
Cardiovascular System 42 | 15,192
Nervous System 42 | 16,725

Target Family

Non-IDG 24 | 12,091
Enzyme 9 | 4,145
Kinase 9 | 634
GPCR 2 | 408
Transcription Factor 1 | 1,400
oGPCR 1 | 421

GO Process

regulation of actin cytoskelet... 46 | 46
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rapamycin-insensitive companion of mTOR RICTOR Tbio Non-IDG -2.79454 597.0 440
SH3 domain-binding protein 1 SH3BP1 Tbio Non-IDG 0.00000 168
Ephrin type-A receptor 5 EPHA5 Tchem Kinase -2.28294 191.7 407
Bone marrow stromal antigen 2 BST2 Tbio Non-IDG -2.59753 424.5 464
Rho guanine nucleotide exchange factor 5 ARHGEF5 Tbio Non-IDG -0.48804 5.75 249
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Sialic acid-binding Ig-like lectin 15 SIGLEC15 Tbio Non-IDG -0.68124 6.27 126
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Rho guanine nucleotide exchange factor 19 ARHGEF19 Tdark Non-IDG -0.56361 4.10 53
Girdin CCDC88A Tbio Non-IDG -1.86485 83.3 197