Development Level

Tbio 17 | 11,651
Tchem 3 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
anophthalmia 1 | 33
cleft palate 1 | 8
corneal opacity 1 | 32
curly tail 1 | 1
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic lethality prior to t... 1 | 278
exencephaly 1 | 2
increased blood urea nitrogen ... 1 | 48
increased mean corpuscular vol... 1 | 92
kinked tail 1 | 2
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pallor 1 | 34
spina bifida 1 | 2
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 18 | 11,493
ovarian cancer 15 | 8,520
osteosarcoma 12 | 7,950
psoriasis 11 | 6,694
Cancer 10 | 2,499
Breast cancer 9 | 3,578
glioblastoma 9 | 5,792
atypical teratoid / rhabdoid tumor 8 | 5,112
medulloblastoma, large-cell 8 | 6,241
non-small cell lung cancer 8 | 2,890
cystic fibrosis 7 | 1,696
ependymoma 7 | 4,679
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
Astrocytoma, Pilocytic 6 | 3,081
adult high grade glioma 6 | 3,801
breast carcinoma 6 | 1,638
invasive ductal carcinoma 6 | 2,951
Kidney cancer 5 | 2,613
astrocytic glioma 5 | 2,597
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Obesity 4 | 678
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Down syndrome 3 | 499
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Kidney disease 3 | 430
Mammary Neoplasms 3 | 425
Osteoporosis 3 | 363
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
Acquired metabolic disease 2 | 336
Adenocarcinoma 2 | 122
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Arthritis, Rheumatoid 2 | 174
Asthma 2 | 385
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
BILIARY TRACT ABNORMALITY 2 | 16
Biliary Tract Diseases 2 | 16
Carcinoma, Hepatocellular 2 | 228
Cholestasis 2 | 155
Chronic obstructive pulmonary disease 2 | 184
Coronary artery disease 2 | 268
Decreased platelet count 2 | 111
Disease Progression 2 | 136
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hydrocephalus 2 | 152
Impaired glucose tolerance 2 | 28
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Liver carcinoma 2 | 240
Liver neoplasms 2 | 130
Lung Neoplasms 2 | 232
Multiple myeloma 2 | 1,332
Nephronophthisis 2 | 80
Neuroblastoma 2 | 80
Orbital separation excessive 2 | 244
Phenotypic variability 2 | 150
Prostate cancer 2 | 175
Proteinuria 2 | 144
Schizophrenia 2 | 1,160
Somatic mutation 2 | 61
Splenomegaly 2 | 190
Thrombocytopenia 2 | 197
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
fibroadenoma 2 | 559
hereditary spastic paraplegia 2 | 318
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Blood and immune system 20 | 16,909
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 9 | 12,091
Transcription Factor 6 | 1,400
Enzyme 5 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

regulation of Wnt signaling pa... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587
Transmembrane protein 237 TMEM237 Tdark Non-IDG -0.23709 2.37 74
Core-binding factor subunit beta CBFB Tchem Transcription Factor -0.78193 5.82 291
R-spondin-3 RSPO3 Tbio Non-IDG -1.33286 23.2 138
Vang-like protein 2 VANGL2 Tbio Non-IDG -2.29322 199.6 158
Transcription factor 7-like 1 TCF7L1 Tbio Transcription Factor -1.20549 17.1 109
Sentrin-specific protease 2 SENP2 Tbio Enzyme -0.25795 1.43 478
Forkhead box protein P3 FOXP3 Tbio Transcription Factor -3.80046 6233.8 1358
Axin-1 AXIN1 Tbio Non-IDG -2.52218 301.0 370