Development Level

Tbio 22 | 11,445
Tchem 6 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal response to tactile s... 1 | 17
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating calcium ... 1 | 36
decreased granulocyte number 1 | 6
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating chloride... 1 | 41
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 25 | 11,493
ovarian cancer 22 | 8,520
osteosarcoma 16 | 7,950
psoriasis 13 | 6,694
ependymoma 12 | 4,679
medulloblastoma, large-cell 11 | 6,241
group 3 medulloblastoma 10 | 4,104
lung cancer 10 | 4,740
Breast cancer 9 | 3,578
glioblastoma 9 | 5,792
Pick disease 8 | 1,894
acute quadriplegic myopathy 8 | 1,158
Kidney cancer 7 | 2,613
atypical teratoid / rhabdoid tumor 7 | 5,112
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
Multiple myeloma 6 | 1,332
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
pituitary cancer 5 | 1,972
progressive supranuclear palsy 5 | 676
subependymal giant cell astrocytoma 5 | 2,287
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Myotonic dystrophy type 1 4 | 17
Renal Cell Carcinoma 4 | 214
Waldenstrons macroglobulinemia 4 | 765
aldosterone-producing adenoma 4 | 665
spina bifida 4 | 1,074
Gastrointestinal stromal tumor 3 | 62
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Pancreatic Neuroendocrine Tumor 3 | 45
Rheumatoid arthritis 3 | 1,191
Spinocerebellar ataxia type 1 3 | 16
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Cancer 2 | 2,499
Cleft Palate 2 | 271
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Dull intelligence 2 | 645
Fuchs' endothelial dystrophy 2 | 24
Gaucher disease type 1 2 | 180
Hamman-Rich syndrome 2 | 34
Hypoplastic mandible condyle 2 | 275
Low intelligence 2 | 645
Mandibular hypoplasia 2 | 275
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Micrognathism 2 | 275
Muscular atrophy 2 | 71
Myotonic dystrophy type 2 2 | 8
Poor school performance 2 | 645
Skin cancer 2 | 469
Uranostaphyloschisis 2 | 167
X- linked recessive 2 | 110
acute myeloid leukemia 2 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
interstitial lung disease 2 | 298
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non primary Sjogren syndrome sicca 2 | 891
obsessive-compulsive disorder 2 | 61
substance-related disorder 2 | 162
tuberculosis and treatment for 6 months 2 | 409
Arachnodactyly 1 | 49
Azoospermia 1 | 110
Barrett's esophagus 1 | 182
Carcinoma, Renal Cell 1 | 124
Chronic tic disorder 1 | 8
Congenital Camptodactyly 1 | 40
Contracture of joint of hand 1 | 30
Gilles de la Tourette syndrome 1 | 47
Gonadoblastoma 1 | 34
Hyperactive behavior 1 | 91
Hyperopia 1 | 70
Progressive relapsing multiple sclerosis 1 | 19
Salivary Gland Neoplasms 1 | 46
Small testicle 1 | 75
Tetralogy of Fallot 1 | 63

Tissue

Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Male tissues 28 | 17,142
Skin and soft tissues 28 | 17,230
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Urinary Tract 27 | 16,678
Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Liver and Pancreas 26 | 16,750

Target Family

Non-IDG 19 | 12,091
Kinase 6 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Process

regulation of RNA splicing 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Muscleblind-like protein 3 MBNL3 Tbio Non-IDG -1.26326 19.8 110
AF4/FMR2 family member 2 AFF2 Tbio Transcription Factor -2.47154 295.5 108
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.65508 52.1 119
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Transformer-2 protein homolog beta TRA2B Tbio Non-IDG -1.61091 39.4 133
RNA-binding motif protein, Y chromosome, family 1 member C RBMY1C Tdark Non-IDG -2.09833 217.2 0
Serine/arginine repetitive matrix protein 4 SRRM4 Tbio Non-IDG -1.08022 11.5 35
Dual specificity protein kinase CLK1 CLK1 Tchem Kinase -1.93720 87.9 156
Bromodomain testis-specific protein BRDT Tchem Epigenetic -1.81331 61.0 111