Development Level

Tbio 35 | 11,445
Tchem 8 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 6 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased vertical activity 2 | 208
hypoactivity 2 | 132
abnormal gait 1 | 69
abnormal testis morphology 1 | 43
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased caudal vertebrae num... 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating potassiu... 1 | 29
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 29 | 11,493
psoriasis 19 | 6,694
osteosarcoma 17 | 7,950
ovarian cancer 17 | 8,520
lung cancer 15 | 4,740
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
Cancer 10 | 2,499
adult high grade glioma 10 | 3,801
ependymoma 10 | 4,679
invasive ductal carcinoma 10 | 2,951
lung adenocarcinoma 10 | 2,716
Breast cancer 9 | 3,578
ductal carcinoma in situ 9 | 1,745
group 3 medulloblastoma 9 | 4,104
interstitial cystitis 9 | 2,312
breast carcinoma 8 | 1,638
diabetes mellitus 8 | 1,728
pituitary cancer 8 | 1,972
Astrocytoma, Pilocytic 7 | 3,081
malignant mesothelioma 7 | 3,232
Autosomal recessive predisposition 5 | 1,442
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Osteoarthritis 5 | 184
Schizophrenia 5 | 1,160
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Premature ovarian failure 4 | 65
Rheumatoid arthritis 4 | 1,191
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
lung carcinoma 4 | 2,843
tuberculosis 4 | 2,010
Anemia 3 | 365
Bipolar Disorder 3 | 666
Congenital heart disease 3 | 93
Coronary artery disease 3 | 268
Down syndrome 3 | 499
Epilepsy 3 | 792
Heart failure 3 | 162
Infertility 3 | 188
Multiple myeloma 3 | 1,332
Obesity 3 | 678
Polycystic ovary syndrome 3 | 360
Pre-Eclampsia 3 | 68
Right atrial isomerism 3 | 29
Visceral heterotaxy 3 | 14
acute quadriplegic myopathy 3 | 1,158
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Acquired metabolic disease 2 | 336
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Bilateral fifth finger clinodactyly 2 | 110
Carcinoma, Hepatocellular 2 | 228
Congenital ocular coloboma (disorder) 2 | 40
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Degenerative polyarthritis 2 | 115
Exophthalmos 2 | 112
Heart disease 2 | 306
Heterotaxy Syndrome 2 | 5
Hypertension 2 | 396
Kidney disease 2 | 430
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Melanoma 2 | 711
Motor delay 2 | 147
Multiple Sclerosis 2 | 540
Multiple synostoses syndrome 2 | 9
Myocardial Ischemia 2 | 169
No development of motor milestones 2 | 147
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Prominent eyes 2 | 96
Prominent globes 2 | 96
Prostatic Neoplasms 2 | 495
Proteinuria 2 | 144
Protruding eyes 2 | 96
Situs ambiguus 2 | 25
Turner syndrome 2 | 28
Unipolar Depression 2 | 250
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
cystic fibrosis and chronic rhinosinusitis 2 | 214
fibroadenoma 2 | 559
head and neck cancer 2 | 271
hepatocellular carcinoma 2 | 547
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Endocrine System 44 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 42 | 16,750
Digestive Tract 41 | 17,369
Male tissues 40 | 17,142
Skin and soft tissues 40 | 17,230
Nervous System 39 | 16,725
Urinary Tract 39 | 16,678
Cardiovascular System 37 | 15,192
Blood and immune system 36 | 16,909
Respiratory system 36 | 16,393

Target Family

Non-IDG 30 | 12,091
Kinase 8 | 634
Enzyme 4 | 4,145
GPCR 2 | 408
Transcription Factor 1 | 1,400

GO Process

regulation of MAPK cascade 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Serine/threonine-protein kinase VRK2 VRK2 Tbio Kinase -1.28897 20.5 123
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Signal transducer CD24 CD24 Tbio Non-IDG 0.00000 0
Embryonic growth/differentiation factor 1 GDF1 Tbio Non-IDG -2.00590 102.6 64
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.11354 130.5 361
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Growth/differentiation factor 6 GDF6 Tbio Non-IDG -2.31035 205.4 110