Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal kidney morphology 1 | 65
abnormal outer ear morphology 1 | 3
anophthalmia 1 | 33
hypoactivity 1 | 132
increased fasted circulating g... 1 | 76
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
osteosarcoma 5 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
medulloblastoma, large-cell 3 | 6,241
Chronic Lymphocytic Leukemia 2 | 262
Kidney cancer 2 | 2,613
Rheumatoid arthritis 2 | 1,191
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Barrett's esophagus 1 | 182
Breast Neoplasms 1 | 445
Cancer 1 | 2,499
Chancroid 1 | 8
Congenital hereditary endothelial dystrophy of cornea 1 | 8
Coronary artery disease 1 | 268
Dental caries 1 | 164
Familial cancer of breast 1 | 12
Fatty liver disease 1 | 103
Heart disease 1 | 306
Hereditary spastic paraplegia 33 1 | 1
Human immunodeficiency virus infectious disease 1 | 138
Idiopathic scoliosis 1 | 31
Insulin Resistance 1 | 72
Liver Cirrhosis, Experimental 1 | 769
Metabolic Syndrome 1 | 20
Metabolic syndrome X 1 | 52
Multiple myeloma 1 | 1,332
Narcolepsy 1 | 72
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
X-linked cerebral adrenoleukodystrophy 1 | 116
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical adenoma 1 | 131
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
fibroadenoma 1 | 559
group 3 medulloblastoma 1 | 4,104
inflammatory breast cancer 1 | 286
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
non diabetic and post-ischemic heart failure 1 | 200
non primary Sjogren syndrome sicca 1 | 891
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Endocrine System 7 | 18,159
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Kinase 4 | 634
Enzyme 2 | 4,145
Non-IDG 1 | 12,091

GO Process

regulation of MAP kinase activ... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Serine/threonine-protein phosphatase with EF-hands 2 PPEF2 Tbio Enzyme -0.26680 1.77 58
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Tribbles homolog 3 TRIB3 Tbio Kinase -1.93599 97.7 421
Hepatocyte growth factor-regulated tyrosine kinase substrate HGS Tbio Enzyme -2.76643 560.1 379
Tribbles homolog 2 TRIB2 Tbio Kinase -1.49133 35.3 157