Development Level

Tbio 9 | 11,651
Tchem 4 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51
decreased leukocyte cell numbe... 1 | 73
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 13 | 11,493
medulloblastoma, large-cell 11 | 6,241
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 9 | 5,112
osteosarcoma 9 | 7,950
ependymoma 8 | 4,679
astrocytic glioma 7 | 2,597
psoriasis 7 | 6,694
adult high grade glioma 6 | 3,801
glioblastoma 6 | 5,792
interstitial cystitis 6 | 2,312
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Kidney cancer 5 | 2,613
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
non-small cell lung cancer 5 | 2,890
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Hepatocellular 3 | 228
Liver carcinoma 3 | 240
Melanoma 3 | 711
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
Adenocarcinoma in situ 2 | 15
Bipolar Disorder 2 | 666
Blastic phase chronic myeloid leukemia 2 | 58
Breast Neoplasms 2 | 445
Cell Transformation, Neoplastic 2 | 97
Cervical cancer 2 | 24
Chronic Myelocytic Leukemia Accelerated Phase 2 | 59
Dermatitis 2 | 157
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Down syndrome 2 | 499
Dull intelligence 2 | 645
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Neoplastic Cell Transformation 2 | 89
Neutropenia 2 | 72
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Skin cancer 2 | 469
Small cell neuroendocrine carcinoma 2 | 2
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
nephrosclerosis 2 | 333
non primary Sjogren syndrome sicca 2 | 891
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819
Adenocarcinoma 1 | 122
Age related macular degeneration 1 | 72
Arthritis, Experimental 1 | 39
Autosomal recessive non-syndromic intellectual disability 1 | 7
Autosomal recessive polycystic kidney disease 1 | 41
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Squamous Cell 1 | 110
Congenital diaphragmatic hernia 1 | 67
DOID:9917 1 | 31
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Familial adenomatous polyposis 1 | 32
Growth Disorders 1 | 35
HER2-positive carcinoma of breast 1 | 21
Infectious disease of lung 1 | 29
Lewy Body Disease 1 | 21
Malignant glioma 1 | 26
Multiple pulmonary infections 1 | 29
Pancreatitis 1 | 123
Paronychia 1 | 7
Recurrent pneumonia 1 | 29
Recurrent pulmonary infections 1 | 29
Silver-Russell syndrome 1 | 39
Underweight 1 | 17
Weight less than 3rd percentile 1 | 17

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Enzyme 7 | 4,145
Kinase 5 | 634
Non-IDG 2 | 12,091
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

regulation of JNK cascade 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-Jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 Tbio Enzyme -2.85543 697.4 180
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.68844 56.5 128
COP9 signalosome complex subunit 5 COPS5 Tbio Non-IDG -2.26989 213.6 374
Serine/threonine-protein kinase ULK4 ULK4 Tbio Kinase -0.84579 9.51 57
E3 ubiquitin-protein ligase SH3RF1 SH3RF1 Tbio Enzyme -1.79855 65.0 114
Insulin-like growth factor 1 receptor IGF1R Tclin Kinase -3.37168 2419.5 1686
Ras-related protein Rap-2a RAP2A Tbio Enzyme -2.10552 120.8 97
Mitogen-activated protein kinase kinase kinase kinase 4 MAP4K4 Tchem Kinase -2.19064 152.6 547
Ephrin type-B receptor 1 EPHB1 Tchem Kinase -1.70013 52.0 389
Rap guanine nucleotide exchange factor 1 RAPGEF1 Tbio Non-IDG -2.41980 281.2 167