Development Level

Tbio 46 | 11,445
Tchem 10 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 4 | 298
hyperactivity 4 | 148
preweaning lethality, incomple... 4 | 499
decreased circulating insulin ... 2 | 76
decreased total body fat amoun... 2 | 207
increased mean corpuscular hem... 2 | 96
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal duodenum morphology 1 | 4
abnormal lens morphology 1 | 81
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal urination 1 | 1
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged adrenal glands 1 | 3
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
polycystic kidney 1 | 15
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
thin ventricular wall 1 | 24

Disease

Carcinoma 48 | 11,493
osteosarcoma 38 | 7,950
ovarian cancer 37 | 8,520
Kidney cancer 27 | 2,613
ependymoma 26 | 4,679
glioblastoma 26 | 5,792
medulloblastoma, large-cell 26 | 6,241
atypical teratoid / rhabdoid tumor 25 | 5,112
Breast cancer 22 | 3,578
psoriasis 22 | 6,694
astrocytic glioma 21 | 2,597
oligodendroglioma 20 | 2,850
Cancer 19 | 2,499
adult high grade glioma 18 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
pancreatic cancer 18 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
lung cancer 16 | 4,740
group 4 medulloblastoma 15 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung adenocarcinoma 15 | 2,716
primitive neuroectodermal tumor 15 | 3,035
Astrocytoma, Pilocytic 14 | 3,081
invasive ductal carcinoma 14 | 2,951
non-small cell lung cancer 14 | 2,890
subependymal giant cell astrocytoma 14 | 2,287
ductal carcinoma in situ 13 | 1,745
malignant mesothelioma 13 | 3,232
group 3 medulloblastoma 12 | 4,104
Pick disease 11 | 1,894
interstitial cystitis 11 | 2,312
cystic fibrosis 10 | 1,696
lung carcinoma 10 | 2,843
primary pancreatic ductal adenocarcinoma 10 | 1,109
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
breast carcinoma 8 | 1,638
pituitary cancer 8 | 1,972
spina bifida 8 | 1,074
tuberculosis 8 | 2,010
ulcerative colitis 8 | 1,819
Intellectual disability 7 | 1,016
cutaneous lupus erythematosus 7 | 1,057
Acquired scoliosis 6 | 281
Alzheimer's disease 6 | 658
Curvature of spine 6 | 282
Dull intelligence 6 | 645
Hypertension 6 | 396
Hypertensive disease 6 | 292
Liver cancer 6 | 604
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Poor school performance 6 | 645
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
dermatomyositis 6 | 966
gastric carcinoma 6 | 807
Aarskog syndrome 5 | 12
Anteverted nostril 5 | 191
Autosomal recessive predisposition 5 | 1,442
Blastic phase chronic myeloid leukemia 5 | 58
Chronic Myelocytic Leukemia Accelerated Phase 5 | 59
Chronic phase chronic myeloid leukemia 5 | 45
Cognitive delay 5 | 608
Cryptorchidism 5 | 296
Down syndrome 5 | 499
Global developmental delay 5 | 608
Low-set, posteriorly rotated ears 5 | 110
Mental and motor retardation 5 | 608
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 5 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 5 | 47
Schizophrenia 5 | 1,160
Short stature 5 | 531
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
Blepharoptosis 4 | 231
Depressive disorder 4 | 409
Downward slant of palpebral fissure 4 | 158
Epilepsy 4 | 792
Everted lower lip vermilion 4 | 54
Feeding difficulties in infancy 4 | 175
Lissencephaly 4 | 69
Low posterior hairline 4 | 52
Melanoma 4 | 711
Muscle Spasticity 4 | 195
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Neuropathy 4 | 261
Parkinson's disease 4 | 392
Prostatic Neoplasms 4 | 495
Short nose 4 | 132
Small head 4 | 374
Small nose 4 | 132
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
primary Sjogren syndrome 4 | 735

Tissue

Blood and immune system 59 | 16,909
Digestive Tract 59 | 17,369
Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Male tissues 59 | 17,142
Respiratory system 59 | 16,393
Skin and soft tissues 59 | 17,230
Cardiovascular System 58 | 15,192
Liver and Pancreas 58 | 16,750
Nervous System 58 | 16,725
Urinary Tract 58 | 16,678

Target Family

Non-IDG 39 | 12,091
Enzyme 10 | 4,145
Kinase 9 | 634
Transcription Factor 1 | 1,400

GO Process

regulation of GTPase activity 59 | 59
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab GTPase-activating protein 1 RABGAP1 Tbio Enzyme -0.72004 3.69 184
Rho guanine nucleotide exchange factor 5 ARHGEF5 Tbio Non-IDG -0.48804 5.75 249
Beta-chimaerin CHN2 Tbio Non-IDG -1.78873 58.0 149
Ephrin type-B receptor 3 EPHB3 Tchem Kinase -1.68968 47.7 409
Ephrin type-A receptor 5 EPHA5 Tchem Kinase -2.28294 191.7 407
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Rapamycin-insensitive companion of mTOR RICTOR Tbio Non-IDG -2.79454 597.0 440
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Myotubularin-related protein 13 SBF2 Tbio Non-IDG -1.38747 24.7 15
Radixin RDX Tbio Non-IDG -2.47844 221.4 333