Development Level

Tbio 61 | 11,445
Tchem 13 | 1,598
Tclin 5 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal head morphology 3 | 10
decreased body weight 3 | 161
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
male infertility 3 | 123
abnormal cranium morphology 2 | 36
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating fructosa... 1 | 30
decreased circulating sodium l... 1 | 22
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased grip strength 1 | 41
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
short tibia 1 | 97
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

ovarian cancer 59 | 8,520
Carcinoma 58 | 11,493
osteosarcoma 46 | 7,950
group 3 medulloblastoma 43 | 4,104
atypical teratoid / rhabdoid tumor 37 | 5,112
psoriasis 37 | 6,694
medulloblastoma, large-cell 35 | 6,241
lung cancer 33 | 4,740
ependymoma 31 | 4,679
glioblastoma 31 | 5,792
malignant mesothelioma 31 | 3,232
primitive neuroectodermal tumor 29 | 3,035
Breast cancer 27 | 3,578
Kidney cancer 27 | 2,613
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
colon cancer 21 | 1,478
non-small cell lung cancer 21 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
Intellectual disability 18 | 1,016
lung adenocarcinoma 18 | 2,716
oligodendroglioma 18 | 2,850
Astrocytoma, Pilocytic 17 | 3,081
nasopharyngeal carcinoma 17 | 1,058
Cancer 16 | 2,499
Microcephaly 15 | 166
Pick disease 15 | 1,894
invasive ductal carcinoma 15 | 2,951
pancreatic cancer 15 | 2,398
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
astrocytic glioma 14 | 2,597
Autosomal recessive predisposition 13 | 1,442
Multiple myeloma 13 | 1,332
Small head 13 | 374
adrenocortical carcinoma 13 | 1,428
breast carcinoma 13 | 1,638
Short stature 12 | 531
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
ductal carcinoma in situ 11 | 1,745
diabetes mellitus 10 | 1,728
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Endometriosis 9 | 540
Schizophrenia 9 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Agenesis of corpus callosum 8 | 83
Downward slant of palpebral fissure 8 | 158
Epilepsy 8 | 792
Joubert syndrome 8 | 66
Seizures 8 | 596
interstitial cystitis 8 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Atopic dermatitis 7 | 952
Dilated ventricles (finding) 7 | 121
Glaucoma 7 | 239
Pachygyria 7 | 41
Sloping forehead 7 | 46
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
juvenile dermatomyositis 7 | 1,187
subependymal giant cell astrocytoma 7 | 2,287
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 6 | 16
Muscle hypotonia 6 | 571
Obesity 6 | 678
Severe mental retardation (I.Q. 20-34) 6 | 99
acute myeloid leukemia 6 | 783
dermatomyositis 6 | 966
non primary Sjogren syndrome sicca 6 | 891
pituitary cancer 6 | 1,972
posterior fossa group B ependymoma 6 | 416
Anteverted nostril 5 | 191
Breast Neoplasms 5 | 445
Cataract 5 | 297
Fetal Growth Retardation 5 | 189
Hypertensive disease 5 | 292
Hypoplastic mandible condyle 5 | 275
Increase in blood pressure 5 | 119
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Lens Opacities 5 | 231
Lissencephaly 5 | 69
Low set ears 5 | 181
Mammary Neoplasms 5 | 425
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Nephronophthisis 5 | 80
Neuroblastoma 5 | 80
Orbital separation excessive 5 | 244
Rheumatoid arthritis 5 | 1,191
Seckel syndrome 5 | 34
esophageal adenocarcinoma 5 | 737
pediatric high grade glioma 5 | 1,064
progressive supranuclear palsy 5 | 676
tuberculosis and treatment for 6 months 5 | 409

Tissue

Endocrine System 83 | 18,159
Female tissues 83 | 17,400
Male tissues 83 | 17,142
Nervous System 83 | 16,725
Blood and immune system 82 | 16,909
Digestive Tract 82 | 17,369
Liver and Pancreas 82 | 16,750
Respiratory system 82 | 16,393
Skin and soft tissues 82 | 17,230
Urinary Tract 82 | 16,678
Cardiovascular System 79 | 15,192

Target Family

Non-IDG 65 | 12,091
Kinase 11 | 634
Enzyme 6 | 4,145
Ion Channel 1 | 344

GO Process

regulation of G2-M transition ... 83 | 83
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 57 kDa CEP57 Tbio Non-IDG -0.98216 11.8 177
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
HAUS augmin-like complex subunit 2 HAUS2 Tbio Non-IDG 0.71 0.12 44
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Potassium voltage-gated channel subfamily H member 5 KCNH5 Tclin Ion Channel -1.20155 17.8 40
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
Centrosomal protein of 41 kDa CEP41 Tdark Non-IDG -0.41185 3.40 46
Centromere protein F CENPF Tbio Non-IDG -2.02939 109.1 186