Development Level

Tbio 13 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased fluid intake 1 | 3
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating calcium ... 1 | 34
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 10 | 8,520
malignant mesothelioma 9 | 3,232
psoriasis 9 | 6,694
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
Carcinoma 7 | 11,493
Cancer 6 | 2,499
atypical teratoid / rhabdoid tumor 6 | 5,112
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
HIV Infections 3 | 102
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Atopic dermatitis 2 | 952
Carcinoma, Hepatocellular 2 | 228
Esophageal Squamous Cell Carcinoma 2 | 77
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Squamous cell carcinoma of esophagus 2 | 77
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Animal Mammary Neoplasms 1 | 136
Arsenic Poisoning 1 | 62
Arthritis 1 | 290
Arthrogryposis 1 | 54
Barrett's esophagus 1 | 182
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Chronic obstructive pulmonary disease 1 | 184
Chronic otitis media 1 | 52
Dentin caries 1 | 5
Dermatologic disorders 1 | 93
Diarrhea 1 | 253
Enamel caries 1 | 8
Endometriosis 1 | 540
Failure to gain weight 1 | 365
Fatigue 1 | 182
Fever 1 | 138
Heart valve disease 1 | 39
Immunologic Deficiency Syndromes 1 | 113
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Lung oat cell carcinoma 1 | 1
Lymphangioma 1 | 9
Lymphedema 1 | 42
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Melanoma 1 | 711
Mesothelioma, Malignant 1 | 105
Osteomyelitis 1 | 42
Pediatric failure to thrive 1 | 365
Recurrent respiratory infections 1 | 141
Skin Diseases 1 | 71
Stomach Neoplasms 1 | 300
Vertical Talus 1 | 25
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
dermatomyositis 1 | 966
ear infection chronic 1 | 52
fibroadenoma 1 | 559
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-inflammatory breast cancer 1 | 66
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
tuberculosis and treatment for 6 months 1 | 409

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Blood and immune system 13 | 16,909
Liver and Pancreas 13 | 16,750
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 3 | 1,400
Enzyme 2 | 4,145
Kinase 1 | 634

GO Process

regulation of G1-S transition ... 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive serine/threonine-protein kinase PLK5 PLK5 Tbio Kinase -0.60609 4.07 119
Protein ecdysoneless homolog ECD Tbio Non-IDG -0.72245 9.93 113
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Podoplanin PDPN Tbio Non-IDG -3.34579 2142.9 847
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.87037 83.7 245
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
PTB-containing, cubilin and LRP1-interacting protein PID1 Tbio Non-IDG -1.78206 64.1 90
Kinesin-like protein KIF14 KIF14 Tbio Non-IDG -1.46037 34.0 93
Proteasome activator complex subunit 1 PSME1 Tbio Non-IDG -1.72313 55.9 233