Development Level

Tbio 13 | 11,651
Tchem 3 | 1,388

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal rib morphology 1 | 10
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased lean body mass 1 | 172
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Carcinoma 13 | 11,493
ovarian cancer 13 | 8,520
osteosarcoma 12 | 7,950
psoriasis 7 | 6,694
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
medulloblastoma, large-cell 6 | 6,241
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Kidney cancer 5 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
Rheumatoid arthritis 4 | 1,191
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
Chronic Lymphocytic Leukemia 3 | 262
Epilepsy 3 | 792
Intellectual disability 3 | 1,016
Roberts syndrome 3 | 15
Seizures 3 | 596
glioblastoma 3 | 5,792
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Anteverted nostril 2 | 191
Asthma 2 | 385
Cognitive delay 2 | 608
Cornelia de Lange syndrome 2 | 21
Dull intelligence 2 | 645
Feeding difficulties in infancy 2 | 175
Global developmental delay 2 | 608
Inverted V-shaped upper lip 2 | 19
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Myocardial Ischemia 2 | 169
Oculodentodigital dysplasia 2 | 14
Open mouth 2 | 45
Pick disease 2 | 1,894
Poor school performance 2 | 645
SC phocomelia syndrome 2 | 4
Short nose 2 | 132
Small nose 2 | 132
Tented mouth 2 | 19
Tented upper lip 2 | 19
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
ependymoma 2 | 4,679
hereditary spastic paraplegia 2 | 318
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
subependymal giant cell astrocytoma 2 | 2,287
Adenocarcinoma 1 | 122
Ascariasis 1 | 7
Burkitt Lymphoma 1 | 20
Bushy eyebrows 1 | 49
Cholera 1 | 34
Common variable immunodeficiency 1 | 101
Convex nasal bridge 1 | 57
Creutzfeldt-Jakob disease 1 | 21
Dermoid cyst 1 | 5
Edema 1 | 81
Epithelial ovarian cancer 1 | 9
Fatal familial insomnia 1 | 10
Generalized hirsutism 1 | 36
Hypertension, Pulmonary 1 | 37
Hypoplasia of nipple 1 | 16
Hypoplastic feet 1 | 66
Idiopathic pulmonary arterial hypertension 1 | 40
Kleefstra syndrome 1 | 12
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Low posterior hairline 1 | 52
Nail disease 1 | 9
Obsessive compulsive behavior 1 | 25
Ocular hypertension 1 | 42
Primary ciliary dyskinesia 1 | 76
Progressive microcephaly 1 | 32
Prominent nasal bridge 1 | 57
Pseudomyxoma peritonei 1 | 6
Pulmonary hypertension 1 | 86
Retinoblastoma 1 | 19
Small hand 1 | 36
Systemic scleroderma 1 | 60
Usher syndrome type 1C 1 | 3
Variant Creutzfeldt-Jakob disease 1 | 16
Vesico-Ureteral Reflux 1 | 33
obsessive-compulsive disorder 1 | 61

Tissue

Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Enzyme 7 | 4,145
Non-IDG 5 | 12,091
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

regulation of DNA replication 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA Tchem Enzyme -2.14505 119.6 506
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform PPP2R1A Tbio Enzyme -1.43130 26.7 308
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.10209 115.2 244
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.49970 327.4 277
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 NUCKS1 Tbio Enzyme -1.43623 29.2 148
DNA-binding protein inhibitor ID-3 ID3 Tbio Transcription Factor -2.36130 229.3 402
E3 ubiquitin-protein ligase RBBP6 RBBP6 Tbio Enzyme -1.36066 29.2 241
Girdin CCDC88A Tbio Non-IDG -1.86485 83.3 197
Ankyrin repeat domain-containing protein 17 ANKRD17 Tbio Non-IDG -1.29191 20.1 120
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432