Development Level

Tchem 4 | 1,598
Tbio 3 | 11,445

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
absent testes 1 | 6
anophthalmia 1 | 33
decreased circulating iron lev... 1 | 32
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Cancer 6 | 2,499
Carcinoma 6 | 11,493
Breast cancer 4 | 3,578
ovarian cancer 4 | 8,520
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Colorectal Neoplasms 2 | 243
Kidney cancer 2 | 2,613
Obesity 2 | 678
Orbital separation excessive 2 | 244
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
fascioscapulohumeral muscular dystrophy 2 | 100
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Acidosis, Respiratory 1 | 1
Arthralgia 1 | 90
Arthritis, Experimental 1 | 39
Breast Neoplasms 1 | 445
Broad nasal tip 1 | 28
Bushy eyebrows 1 | 49
Class III malocclusion 1 | 78
Craniofacial Abnormalities 1 | 151
Decreased platelet count 1 | 111
Dental caries 1 | 164
Downward slant of palpebral fissure 1 | 158
Dyslexia 1 | 43
Encephalitis 1 | 64
Epidermolysis bullosa 1 | 21
Esophageal Neoplasms 1 | 69
Everted lower lip vermilion 1 | 54
Fine hair 1 | 42
Fragile skin 1 | 18
Fuhrmann syndrome 1 | 7
Galloway-Mowat syndrome 1 | 15
Glomerular filtration rate decreased 1 | 7
Gynecomastia 1 | 64
Hepatic encephalopathy 1 | 27
Holt-Oram syndrome 1 | 12
Hypertrophy of lower jaw 1 | 78
Hypophosphatemia 1 | 40
Hypotrophic malar bone 1 | 129
INTERSTITIAL LUNG DISEASE, NEPHROTIC SYNDROME, AND EPIDERMOLYSIS BULLOSA, CONGENITAL 1 | 1
IgG Deficiency 1 | 22
Immunologic Deficiency Syndromes 1 | 113
Increased IgM levels 1 | 16
Increased size of mandible 1 | 78
Knee joint valgus deformity 1 | 56
Learning disability 1 | 17
Limited elbow extension 1 | 19
Lymphadenopathy 1 | 62
Lymphoma 1 | 81
Lymphoproliferative syndrome 1 | 58
Malar flattening 1 | 129
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Experimental 1 | 154
Mandibular hyperplasia 1 | 78
Meningitis 1 | 67
Microsatellite Instability 1 | 12
Mild Mental Retardation 1 | 70
Muscle Weakness 1 | 170
Myocardial Reperfusion Injury 1 | 37
Narrow thorax 1 | 53
Osteomalacia 1 | 35
Ovarian Cysts 1 | 41
Ovarian Neoplasms 1 | 102
Platyspondyly 1 | 56
Pre-Eclampsia 1 | 68
Protruding lower lip 1 | 54
Respiratory Distress Syndrome 1 | 15
Rickets 1 | 49
Rotting teeth 1 | 73
Round face 1 | 45
Round, full face 1 | 45
Skeletal muscle neoplasm 1 | 8
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Sparse scalp hair 1 | 42
Thick vermilion border 1 | 25
Thrombocytopenia 1 | 197
Tubular atrophy 1 | 10
X- linked recessive 1 | 110
mandibular excess (physical finding) 1 | 78
non-small cell lung cancer and chronic obstructive pulmonary disease 1 | 8
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Liver and Pancreas 6 | 16,750

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

regulation of BMP signaling pa... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Secreted frizzled-related protein 5 SFRP5 Tbio Non-IDG -1.81796 74.9 180
Integrin alpha-3 ITGA3 Tchem Non-IDG -2.08360 104.1 587
E3 ubiquitin-protein ligase XIAP XIAP Tchem Enzyme -3.13488 1375.8 504
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Transcription factor AP-2-beta TFAP2B Tbio Transcription Factor -1.74089 52.9 225
Secreted frizzled-related protein 4 SFRP4 Tbio Non-IDG -2.01200 108.0 262