Development Level

Tbio 25 | 10,625
Tdark 3 | 7,003
Tchem 2 | 1,890

IMPC Term

abnormal behavioral response t... 1 | 52
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
cardiovascular system phenotyp... 1 | 35
decreased heart rate variabili... 1 | 11
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
increased blood urea nitrogen ... 1 | 44
increased heart rate 1 | 17
increased leukocyte cell numbe... 1 | 37
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
shortened RR interval 1 | 19
shortened ST segment 1 | 9
thin tail 1 | 1

Disease

osteosarcoma 14 | 7,933
Breast cancer 13 | 3,094
medulloblastoma, large-cell 12 | 6,234
ovarian cancer 12 | 8,484
Cancer 10 | 2,346
malignant mesothelioma 9 | 3,162
glioblastoma 8 | 5,572
Male infertility 7 | 170
Neoplastic Syndromes, Hereditary 7 | 48
atypical teratoid / rhabdoid tumor 7 | 4,369
lung cancer 7 | 4,466
psoriasis 7 | 6,685
Mammary Neoplasms 6 | 410
group 3 medulloblastoma 6 | 2,254
invasive ductal carcinoma 6 | 2,950
lung adenocarcinoma 6 | 2,713
primitive neuroectodermal tumor 6 | 3,031
Carcinoma 5 | 2,147
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Nijmegen breakage syndrome 5 | 23
ependymoma 5 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
non-small cell lung cancer 5 | 2,798
Fanconi's anemia 4 | 50
Infertility 4 | 163
Lynch syndrome 4 | 33
Melanoma 4 | 261
Microcephaly 4 | 149
Rheumatoid Arthritis 4 | 1,160
astrocytic glioma 4 | 2,241
atypical teratoid/rhabdoid tumor 4 | 1,095
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
sonic hedgehog group medulloblastoma 4 | 1,482
Ataxia telangiectasia 3 | 31
Endometrial carcinoma 3 | 18
Hereditary Nonpolyposis Colorectal Cancer 3 | 13
Hereditary Nonpolyposis Colorectal Neoplasms 3 | 8
Multiple myeloma 3 | 1,327
Peripheral Neuropathy 3 | 303
Prostatic Neoplasms 3 | 471
colon cancer 3 | 1,475
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
nasopharyngeal carcinoma 3 | 1,056
oligodendroglioma 3 | 2,849
ovarian neoplasm 3 | 97
pancreatic cancer 3 | 2,300
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 2,087
Adenocarcinoma of lung (disorder) 2 | 48
Adenoma 2 | 165
Bloom syndrome 2 | 30
Breast Cancer, Familial 2 | 12
Chronic Lymphocytic Leukemia 2 | 242
Colorectal Neoplasms 2 | 217
Colorectal cancer, hereditary nonpolyposis, type 1 2 | 4
Endometrial Neoplasms 2 | 50
Endometriosis 2 | 535
Esophageal Neoplasms 2 | 67
Familial adenomatous polyposis 2 | 31
Head and Neck Neoplasms 2 | 23
IGA Glomerulonephritis 2 | 454
Malignant neoplasm of breast 2 | 63
Microsatellite Instability 2 | 12
Pancreatic Neoplasm 2 | 79
Pick disease 2 | 1,893
Sebaceous adenoma 2 | 11
Stomach Neoplasms 2 | 282
Torre-Muir syndrome 2 | 3
Turcot syndrome (disorder) 2 | 5
Uterine fibroid 2 | 29
Werner syndrome 2 | 29
acute myeloid leukemia 2 | 780
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
breast carcinoma 2 | 1,614
dermatomyositis 2 | 933
diabetes mellitus 2 | 1,663
medulloblastoma 2 | 1,524
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung carcinoma 2 | 413
posterior fossa group B ependymoma 2 | 1,530
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
Anemia 1 | 252
Basal cell carcinoma 1 | 29
Bipolar Disorder 1 | 266
Bladder Neoplasm 1 | 109
Cerebellar Ataxia 1 | 72
Gastric leiomyoma 1 | 3
Germ cell cancer 1 | 4
Immune system cancer 1 | 38
Mammary Neoplasms, Experimental 1 | 150
Mesothelioma 1 | 40
Myeloid Leukemia 1 | 19
Pontocerebellar hypoplasia 1 | 29
Roberts syndrome 1 | 16
Seckel syndrome 1 | 34
Telangiectasis 1 | 20
Trichorhinophalangeal syndrome type II 1 | 14

Tissue

Blood and immune system 30 | 17,995
Endocrine System 30 | 18,512
Female tissues 30 | 18,647
Male tissues 30 | 17,969
Nervous System 30 | 18,561
Skin and soft tissues 30 | 18,115
Urinary Tract 30 | 18,444
Cardiovascular System 29 | 17,958
Digestive Tract 29 | 18,473
Liver and Pancreas 29 | 18,136
Respiratory system 28 | 17,484

Target Family

Non-IDG 25 | 11,971
Enzyme 3 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

reciprocal meiotic recombinati... 30 | 30
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Double-strand break repair protein MRE11A MRE11 Tbio Non-IDG -1.95631 90.0 412
Synaptonemal complex central element protein 3 SYCE3 Tdark Non-IDG -0.73316 6.63 5
Testis-expressed sequence 11 protein TEX11 Tbio Non-IDG -0.99022 10.6 50
MutS protein homolog 4 MSH4 Tbio Non-IDG -1.85039 70.8 78
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.30956 203.0 132
Probable E3 SUMO-protein ligase RNF212 RNF212 Tbio Enzyme -0.79452 8.16 77
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.45589 286.4 377
DNA repair protein RAD51 homolog 3 RAD51C Tbio Non-IDG -1.86175 80.1 231
DNA repair protein XRCC2 XRCC2 Tbio Non-IDG -2.72198 465.9 235
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.74283 538.7 441