Development Level

Tbio 24 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

male infertility 4 | 123
female infertility 3 | 60
embryonic lethality prior to t... 2 | 278
shortened RR interval 2 | 17
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased heart rate variabili... 1 | 13
decreased startle reflex 1 | 75
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
shortened ST segment 1 | 10

Disease

Carcinoma 19 | 11,493
osteosarcoma 15 | 7,950
ovarian cancer 12 | 8,520
Breast cancer 11 | 3,578
medulloblastoma, large-cell 10 | 6,241
group 3 medulloblastoma 9 | 4,104
glioblastoma 8 | 5,792
malignant mesothelioma 8 | 3,232
psoriasis 8 | 6,694
Cancer 7 | 2,499
Male infertility 7 | 206
atypical teratoid / rhabdoid tumor 7 | 5,112
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Short stature 6 | 531
ependymoma 6 | 4,679
lung cancer 6 | 4,740
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
Fanconi anemia 5 | 56
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Nijmegen breakage syndrome 5 | 24
Small head 5 | 374
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
Chromosome Breakage 4 | 36
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Increased chromosomal breakage 4 | 27
Infertility 4 | 188
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Microcephaly 4 | 166
Poor school performance 4 | 645
astrocytic glioma 4 | 2,597
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
Acquired scoliosis 3 | 281
Almond-shaped eyes 3 | 23
Ataxia telangiectasia 3 | 34
Curvature of spine 3 | 282
Decreased platelet count 3 | 111
Irregular hyperpigmentation 3 | 33
Leukopenia 3 | 72
Liver cancer 3 | 604
Melanoma 3 | 711
Premature ovarian failure 3 | 65
Prostatic Neoplasms 3 | 495
Pyridoxine-responsive sideroblastic anemia 3 | 17
Radial aplasia/hypoplasia 3 | 29
Rheumatoid arthritis 3 | 1,191
Short palpebral fissure 3 | 38
Thrombocytopenia 3 | 197
Xeroderma pigmentosum 3 | 43
adult high grade glioma 3 | 3,801
colon cancer 3 | 1,478
hypopigmented skin patch 3 | 59
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
Anxiety 2 | 136
Anxiety disease 2 | 113
Attention deficit hyperactivity disorder 2 | 278
Choreatic disease 2 | 52
Chronic Lymphocytic Leukemia 2 | 262
Delayed bone age 2 | 136
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Epilepsy 2 | 792
Fatigue 2 | 182
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Muscle Hypertonia 2 | 88
Muscle Spasticity 2 | 195
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Weight decreased 2 | 103
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
hepatocellular carcinoma 2 | 547
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 29 | 18,159
Female tissues 27 | 17,400
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634

GO Process

reciprocal meiotic recombinati... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
Probable E3 SUMO-protein ligase RNF212 RNF212 Tbio Enzyme -0.94925 8.45 87
DNA repair and recombination protein RAD54B RAD54B Tbio Non-IDG -1.41173 28.9 153
Testis-expressed protein 19 TEX19 Tdark Non-IDG -0.56427 3.47 39
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
Homologous-pairing protein 2 homolog PSMC3IP Tbio Non-IDG -0.97122 14.2 48
MutS protein homolog 4 MSH4 Tbio Non-IDG -1.85065 67.5 94
Testis-expressed protein 11 TEX11 Tbio Non-IDG -1.10386 11.2 57
Cyclin N-terminal domain-containing protein 1 CNTD1 Tbio Non-IDG -0.70615 5.39 69
Type 2 DNA topoisomerase 6 subunit B-like C11orf80 Tbio Non-IDG -0.17609 1.50 9