Development Level

Tbio 17 | 11,445
Tchem 15 | 1,598
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
abnormal embryo size 1 | 220
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality 1 | 28
thrombocytopenia 1 | 56

Disease

ovarian cancer 27 | 8,520
psoriasis 26 | 6,694
Carcinoma 25 | 11,493
glioblastoma 25 | 5,792
lung cancer 24 | 4,740
osteosarcoma 24 | 7,950
Astrocytoma, Pilocytic 20 | 3,081
Cancer 20 | 2,499
lung carcinoma 20 | 2,843
medulloblastoma, large-cell 19 | 6,241
ependymoma 18 | 4,679
invasive ductal carcinoma 18 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
lung adenocarcinoma 16 | 2,716
Breast cancer 15 | 3,578
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
pancreatic cancer 14 | 2,398
Liver Cirrhosis, Experimental 13 | 769
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
ulcerative colitis 13 | 1,819
Hypertension 12 | 396
breast carcinoma 12 | 1,638
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
tuberculosis 12 | 2,010
adult high grade glioma 11 | 3,801
oligodendroglioma 11 | 2,850
Schizophrenia 10 | 1,160
diabetes mellitus 10 | 1,728
Kidney cancer 9 | 2,613
Rheumatoid arthritis 9 | 1,191
group 3 medulloblastoma 9 | 4,104
juvenile dermatomyositis 9 | 1,187
pituitary cancer 9 | 1,972
Autosomal recessive predisposition 8 | 1,442
Down syndrome 8 | 499
dermatomyositis 8 | 966
group 4 medulloblastoma 8 | 1,855
Duchenne muscular dystrophy 7 | 601
astrocytoma 7 | 1,146
mucosa-associated lymphoid tissue lymphoma 7 | 484
subependymal giant cell astrocytoma 7 | 2,287
Alzheimer's disease 6 | 658
Arthritis 6 | 290
Bipolar Disorder 6 | 666
Obesity 6 | 678
Prostatic Neoplasms 6 | 495
cutaneous lupus erythematosus 6 | 1,057
fibroadenoma 6 | 559
non-small cell lung carcinoma 6 | 317
primitive neuroectodermal tumor 6 | 3,035
Depressive disorder 5 | 409
Heart disease 5 | 306
Mental Depression 5 | 333
Multiple myeloma 5 | 1,332
Pneumonia 5 | 174
Vascular disease 5 | 319
active ulcerative colitis 5 | 764
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
colon cancer 5 | 1,478
esophageal adenocarcinoma 5 | 737
pancreatic carcinoma 5 | 562
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
urothelial carcinoma 5 | 318
Amyotrophic lateral sclerosis 4 | 451
Asthma 4 | 385
Atherosclerosis 4 | 291
Autistic Disorder 4 | 364
Breast Neoplasms 4 | 445
Chronic obstructive pulmonary disease 4 | 184
Colorectal Neoplasms 4 | 243
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Malaria 4 | 160
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Migraine 4 | 83
Multiple Sclerosis 4 | 540
Myocardial Ischemia 4 | 169
Neoplasm Metastasis 4 | 168
Type 1 Diabetes Mellitus Treatment Adjunct 4 | 4
Type 2 Diabetes Mellitus Treatment Adjunct 4 | 7
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
gastric cancer 4 | 459
gastric carcinoma 4 | 807
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
hepatocellular carcinoma 4 | 547
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
Becker muscular dystrophy 3 | 191
Pick disease 3 | 1,894
acute myeloid leukemia 3 | 783

Tissue

Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Skin and soft tissues 41 | 17,230
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Respiratory system 40 | 16,393
Blood and immune system 39 | 16,909
Cardiovascular System 39 | 15,192
Urinary Tract 39 | 16,678

Target Family

Non-IDG 28 | 12,091
GPCR 5 | 408
Kinase 4 | 634
Enzyme 3 | 4,145
Ion Channel 1 | 344

GO Process

receptor internalization 41 | 41
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Leukocyte immunoglobulin-like receptor subfamily B member 1 LILRB1 Tbio Non-IDG -2.22487 181.7 0
ADM ADM Tbio Non-IDG -3.27504 1889.0 381
CD81 antigen CD81 Tchem Non-IDG -2.77049 534.4 771
Acetylcholinesterase ACHE Tclin Enzyme -3.49768 2470.5 505
G protein-coupled receptor kinase 4 GRK4 Tchem Kinase -1.71379 54.8 171
E3 ubiquitin-protein ligase NEDD4 NEDD4 Tchem Enzyme -2.44046 259.8 167