Development Level

Tbio 154 | 10,625
Tdark 45 | 7,003
Tchem 10 | 1,890

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 4 | 148
preweaning lethality, incomple... 4 | 260
abnormal lens morphology 3 | 73
embryonic lethality prior to t... 3 | 187
abnormal behavior 2 | 226
decreased body length 2 | 108
decreased body weight 2 | 174
enlarged heart 2 | 111
increased fasted circulating g... 2 | 68
increased mean corpuscular vol... 2 | 91
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
hyperactivity 1 | 108
increased circulating chloride... 1 | 43
increased circulating serum al... 1 | 25
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 93 | 8,484
lung cancer 78 | 4,466
osteosarcoma 71 | 7,933
medulloblastoma, large-cell 55 | 6,234
psoriasis 48 | 6,685
Multiple myeloma 38 | 1,327
diabetes mellitus 38 | 1,663
group 3 medulloblastoma 37 | 2,254
colon cancer 34 | 1,475
malignant mesothelioma 32 | 3,162
glioblastoma 31 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
atypical teratoid / rhabdoid tumor 26 | 4,369
Diamond-Blackfan anemia 23 | 28
Waldenstrons macroglobulinemia 23 | 765
acute quadriplegic myopathy 23 | 1,157
invasive ductal carcinoma 21 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
oligodendroglioma 18 | 2,849
sonic hedgehog group medulloblastoma 18 | 1,482
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
non-small cell lung cancer 16 | 2,798
pediatric high grade glioma 16 | 2,712
Stomach Neoplasms 15 | 282
Disease Progression 14 | 125
ependymoma 14 | 2,514
Anemia, Diamond-Blackfan 13 | 15
Breast cancer 13 | 3,094
subependymal giant cell astrocytoma 13 | 2,287
acute myeloid leukemia 12 | 780
cystic fibrosis 12 | 1,665
primitive neuroectodermal tumor 12 | 3,031
Cancer 11 | 2,346
Carcinoma 11 | 2,147
adult high grade glioma 11 | 2,148
Bowen-Conradi syndrome 10 | 16
astrocytic glioma 10 | 2,241
cutaneous lupus erythematosus 10 | 1,056
pancreatic cancer 10 | 2,300
pilocytic astrocytoma 10 | 3,086
Anemia 9 | 252
Mammary Neoplasms 9 | 410
astrocytoma 9 | 1,493
dermatomyositis 9 | 933
atypical teratoid/rhabdoid tumor 8 | 1,095
juvenile dermatomyositis 8 | 1,189
lung adenocarcinoma 8 | 2,713
Rheumatoid Arthritis 7 | 1,160
group 4 medulloblastoma 7 | 1,875
mucosa-associated lymphoid tissue lymphoma 7 | 480
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
pituitary cancer 7 | 1,972
adrenocortical carcinoma 6 | 1,427
inflammatory breast cancer 6 | 404
non primary Sjogren syndrome sicca 6 | 840
Pick disease 5 | 1,893
Polycystic Ovary Syndrome 5 | 332
Prostatic Neoplasms 5 | 471
Systemic scleroderma 5 | 66
Treacher Collins syndrome 5 | 29
hepatocellular carcinoma 5 | 532
medulloblastoma 5 | 1,524
posterior fossa group B ependymoma 5 | 1,530
spina bifida 5 | 1,064
tuberculosis and treatment for 6 months 5 | 686
Intellectual disability 4 | 573
Parkinson Disease 4 | 102
Shwachman-Diamond syndrome 4 | 16
X-linked cerebral adrenoleukodystrophy 4 | 115
breast carcinoma 4 | 1,614
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 832
glioblastoma multiforme 4 | 347
non diabetic and post-ischemic heart failure 4 | 200
pancreatic carcinoma 4 | 567
Animal Mammary Neoplasms 3 | 136
Glaucoma 3 | 134
Irregular astigmatism 3 | 11
Lymphoid leukemia 3 | 69
Mammary Neoplasms, Experimental 3 | 150
Melanoma 3 | 261
Multiple Sclerosis 3 | 498
Neoplasm Invasiveness 3 | 127
Neurodegenerative disease 3 | 383
Obesity 3 | 616
Osteoporosis 3 | 257
Peripheral Neuropathy 3 | 303
Perlman syndrome 3 | 9
Renal Cell Carcinoma 3 | 199
Vascular disease 3 | 281
Weight Gain 3 | 87
active Crohn's disease 3 | 918
gastric cancer 3 | 430
primary Sjogren syndrome 3 | 789
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Arthritis 2 | 248
Atherosclerosis 2 | 275
Gastric antral vascular ectasia 2 | 11
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499

Tissue

Blood and immune system 208 | 17,995
Digestive Tract 208 | 18,473
Female tissues 208 | 18,647
Liver and Pancreas 208 | 18,136
Male tissues 208 | 17,969
Nervous System 208 | 18,561
Cardiovascular System 207 | 17,958
Endocrine System 207 | 18,512
Urinary Tract 207 | 18,444
Respiratory system 206 | 17,484
Skin and soft tissues 206 | 18,115

Target Family

Non-IDG 161 | 11,971
Enzyme 39 | 4,146
Kinase 6 | 634
Epigenetic 3 | 242

GO Process

rRNA processing 209 | 209
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U3 small nucleolar RNA-interacting protein 2 RRP9 Tbio Non-IDG -0.95790 8.59 56
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.66015 45.9 60
60S ribosomal protein L18 RPL18 Tbio Non-IDG -1.73537 50.7 134
Bystin BYSL Tbio Non-IDG -1.20821 15.6 54
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39563 24.2 45
Nucleolar complex protein 4 homolog NOC4L Tdark Non-IDG 0.08 2.08 40
U3 small nucleolar RNA-associated protein 6 homolog UTP6 Tbio Non-IDG -1.00948 10.4 87
U3 small nucleolar RNA-associated protein 14 homolog A UTP14A Tdark Non-IDG -0.37115 2.10 96
WD repeat-containing protein 75 WDR75 Tdark Non-IDG -0.40457 2.42 13
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150