Development Level

Tbio 169 | 11,651
Tdark 27 | 6,593
Tchem 8 | 1,388

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 6 | 239
increased startle reflex 4 | 112
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating insulin ... 2 | 76
enlarged heart 2 | 210
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal eye posterior chamber... 1 | 1
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
decreased NK cell number 1 | 2
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating chloride... 1 | 41
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
prolonged QT interval 1 | 38

Disease

ovarian cancer 93 | 8,520
Carcinoma 86 | 11,493
lung cancer 77 | 4,740
osteosarcoma 74 | 7,950
medulloblastoma, large-cell 56 | 6,241
psoriasis 50 | 6,694
group 3 medulloblastoma 46 | 4,104
diabetes mellitus 38 | 1,728
Multiple myeloma 37 | 1,332
colon cancer 34 | 1,478
atypical teratoid / rhabdoid tumor 33 | 5,112
glioblastoma 33 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
malignant mesothelioma 31 | 3,232
Diamond-Blackfan anemia 25 | 31
Waldenstrons macroglobulinemia 23 | 765
acute quadriplegic myopathy 21 | 1,158
invasive ductal carcinoma 21 | 2,951
Breast cancer 20 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
ependymoma 19 | 4,679
adult high grade glioma 18 | 3,801
oligodendroglioma 18 | 2,850
Kidney cancer 16 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
Anemia 15 | 365
Cleft Palate 15 | 271
Stomach Neoplasms 15 | 300
Uranostaphyloschisis 15 | 167
non-small cell lung cancer 15 | 2,890
Delayed Puberty 14 | 97
Disease Progression 14 | 136
primitive neuroectodermal tumor 14 | 3,035
Abnormality of the urinary system 13 | 21
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Cardiac Arrhythmia 13 | 103
Cardiac conduction abnormalities 13 | 78
Conduction disorder of the heart 13 | 79
EKG abnormalities 13 | 78
Electrocardiogram abnormal 13 | 81
Electrocardiogram change 13 | 78
Fatigue 13 | 182
Hand deformities 13 | 32
Intermittent migraine headaches 13 | 68
Migraine Disorders 13 | 76
Pallor 13 | 40
cystic fibrosis 13 | 1,696
genital abnormal 13 | 17
reproductive system abnormality 13 | 17
subependymal giant cell astrocytoma 13 | 2,287
acute myeloid leukemia 12 | 783
Cancer 11 | 2,499
astrocytic glioma 11 | 2,597
pancreatic cancer 11 | 2,398
Adenocarcinoma of lung 10 | 142
Bowen-Conradi syndrome 10 | 16
Disease Models, Animal 10 | 155
cutaneous lupus erythematosus 10 | 1,057
pediatric high grade glioma 10 | 1,064
sonic hedgehog group medulloblastoma 10 | 467
Astrocytoma, Pilocytic 9 | 3,081
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
astrocytoma 9 | 1,146
dermatomyositis 9 | 966
group 4 medulloblastoma 9 | 1,855
juvenile dermatomyositis 9 | 1,187
Rheumatoid arthritis 8 | 1,191
lung adenocarcinoma 8 | 2,716
non primary Sjogren syndrome sicca 8 | 891
Autosomal recessive predisposition 7 | 1,442
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Intellectual disability 7 | 1,016
Mental and motor retardation 7 | 608
Short stature 7 | 531
mucosa-associated lymphoid tissue lymphoma 7 | 484
pituitary cancer 7 | 1,972
Pick disease 6 | 1,894
Systemic scleroderma 6 | 60
adrenocortical carcinoma 6 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Failure to gain weight 5 | 365
Feeding difficulties 5 | 127
Osteoporosis 5 | 363
Pediatric failure to thrive 5 | 365
Prostatic Neoplasms 5 | 495
Reticulocytopenia 5 | 10
Treacher Collins syndrome 5 | 27
breast carcinoma 5 | 1,638
hepatocellular carcinoma 5 | 547
spina bifida 5 | 1,074
Dull intelligence 4 | 645
Schizophrenia 4 | 1,160
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
non diabetic and post-ischemic heart failure 4 | 200
pancreatic carcinoma 4 | 562
ulcerative colitis 4 | 1,819

Tissue

Blood and immune system 203 | 16,909
Digestive Tract 203 | 17,369
Endocrine System 203 | 18,159
Female tissues 203 | 17,400
Liver and Pancreas 203 | 16,750
Male tissues 203 | 17,142
Nervous System 203 | 16,725
Respiratory system 203 | 16,393
Skin and soft tissues 203 | 17,230
Urinary Tract 203 | 16,678
Cardiovascular System 202 | 15,192

Target Family

Non-IDG 155 | 12,091
Enzyme 40 | 4,145
Kinase 6 | 634
Epigenetic 3 | 242

GO Process

rRNA processing 204 | 204
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.22337 16.5 217
Ribonuclease P protein subunit p25 RPP25 Tbio Enzyme -1.05396 10.6 62
WD repeat-containing protein 18 WDR18 Tbio Non-IDG -1.69131 43.0 108
Testis-expressed protein 10 TEX10 Tdark Non-IDG -0.59960 4.28 21
mRNA turnover protein 4 homolog MRTO4 Tbio Non-IDG -1.05881 10.9 175
PIH1 domain-containing protein 1 PIH1D1 Tbio Non-IDG -0.84144 8.09 158
Nucleolar and coiled-body phosphoprotein 1 NOLC1 Tbio Non-IDG -1.62313 48.1 216
Probable rRNA-processing protein EBP2 EBNA1BP2 Tbio Non-IDG -1.54043 34.9 87
Ribonuclease P protein subunit p29 POP4 Tbio Enzyme -1.56086 36.1 72
U3 small nucleolar ribonucleoprotein protein IMP3 IMP3 Tbio Non-IDG -0.34242 1.83 146