Development Level

Tbio 5 | 11,445
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal allantois morphology 1 | 8
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
embryonic lethality prior to t... 1 | 278

Disease

Carcinoma 7 | 11,493
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
nasopharyngeal carcinoma 4 | 1,058
psoriasis 4 | 6,694
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
Adenocarcinoma of lung 2 | 142
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Disease Models, Animal 2 | 155
Schizophrenia 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
ependymoma 2 | 4,679
hepatocellular carcinoma 2 | 547
neural tube defect 2 | 9
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
Abruptio Placentae 1 | 3
Acute lymphoid leukemia 1 | 25
Acute promyelocytic leukemia, FAB M3 1 | 11
Adverse reaction to drug 1 | 61
Alzheimer's disease 1 | 658
Arthritis, Rheumatoid 1 | 174
Astrocytoma, Pilocytic 1 | 3,081
Bile duct adenoma 1 | 3
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Cardiovascular system disease 1 | 246
Cleft Lip 1 | 141
Cleft Palate 1 | 271
Congenital heart disease 1 | 93
Down syndrome 1 | 499
Drug-Related Side Effects and Adverse Reactions 1 | 62
Gaucher disease type 1 1 | 180
Homocystinuria 1 | 21
Hyperhomocysteinemia 1 | 37
Kidney cancer 1 | 2,613
Lesch-Nyhan syndrome 1 | 12
Leukemia, Myelocytic, Acute 1 | 120
Liver Neoplasms, Experimental 1 | 59
Lymphoma, Non-Hodgkin 1 | 24
Malignant mesothelioma of pleura 1 | 7
Mammary Neoplasms 1 | 425
Megaloblastic anemia 1 | 18
Methylmalonic acidemia 1 | 37
Multiple myeloma 1 | 1,332
Myocardial Ischemia 1 | 169
Nervous System Diseases 1 | 53
Neural Tube Defects 1 | 31
Neural tube defect, folate-sensitive 1 | 4
Neural tube defects, folate-sensitive 1 | 2
Pathological gambling 1 | 15
Polycystic ovary syndrome 1 | 360
Potocki-Luspski syndrome 1 | 5
Purine nucleoside phosphorylase deficiency 1 | 11
Rheumatoid arthritis 1 | 1,191
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 459
gastric carcinoma 1 | 807
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
nephrosclerosis 1 | 333
nervous system disorder 1 | 53
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 2 | 12,091

GO Process

purine nucleobase biosynthetic... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GMP synthase [glutamine-hydrolyzing] GMPS Tbio Enzyme -2.48490 295.1 194
C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 Tbio Enzyme -1.97029 90.6 101
Multifunctional protein ADE2 PAICS Tbio Non-IDG -2.19877 143.7 209
Trifunctional purine biosynthetic protein adenosine-3 GART Tclin Non-IDG -2.26480 181.2 139
Monofunctional C1-tetrahydrofolate synthase, mitochondrial MTHFD1L Tbio Enzyme -1.66972 40.2 102
Amidophosphoribosyltransferase PPAT Tclin Enzyme -1.75730 56.1 198
Serine hydroxymethyltransferase, cytosolic SHMT1 Tbio Enzyme -2.58690 370.4 181