Development Level

Tbio 20 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal behavior 2 | 298
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased heart rate variabili... 1 | 7
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
narrow eye opening 1 | 12
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 16 | 11,493
ovarian cancer 16 | 8,520
osteosarcoma 9 | 7,950
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
Pick disease 7 | 1,894
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
primitive neuroectodermal tumor 7 | 3,035
diabetes mellitus 6 | 1,728
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
Multiple myeloma 5 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Osteopetrosis 4 | 43
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
Failure to gain weight 3 | 365
Hyperglycemia 3 | 137
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Sensorineural hearing loss 3 | 106
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Anemia 2 | 365
Argentine hemorrhagic fever 2 | 10
Cutis Laxa 2 | 39
Duchenne muscular dystrophy 2 | 601
Enlarged vestibular aqueduct 2 | 10
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Heart failure 2 | 162
Hepatomegaly 2 | 285
Hypertension 2 | 396
Kidney disease 2 | 430
Lymphoma, Follicular 2 | 18
Metabolic acidosis 2 | 90
Nephrocalcinosis 2 | 35
Pallor 2 | 40
Poor growth 2 | 114
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE 2 | 3
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
Very poor growth 2 | 114
Vomiting 2 | 116
adrenocortical carcinoma 2 | 1,428
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
limb girdle muscular dystrophy 2A 2 | 213
non-small cell lung cancer 2 | 2,890
tuberculosis 2 | 2,010
ANONYCHIA 1 | 20
Alkaline phosphatase serum increased 1 | 29
Autoimmune thyroiditis 1 | 27
Brain Injuries 1 | 65
Bushy eyebrows 1 | 49
Calcinosis 1 | 70
Corneal edema 1 | 14
Dehydration 1 | 40
Elevated heart rate 1 | 25
Fuchs' endothelial dystrophy 1 | 24
Goiter 1 | 38
Hereditary elliptocytosis 1 | 22
Hypokalemia 1 | 52
Hypokalemic periodic paralysis 1 | 11
Increased calcium level in kidney 1 | 21
Infection of bone 1 | 19
Ophthalmoparesis 1 | 11
Osteopetrosis autosomal recessive 1 1 | 2
Osteopetrosis, Autosomal Recessive 1 1 | 2
Pathological fracture 1 | 20
Pigmented villonodular synovitis 1 | 9
Precancerous Conditions 1 | 80
Pulmonary emphysema 1 | 48
Rotting teeth 1 | 73
Sickle Cell Anemia 1 | 53
Tetany 1 | 18
Thick vermilion border 1 | 25

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Blood and immune system 26 | 16,909
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Enzyme 20 | 4,145
Non-IDG 3 | 12,091
Transporter 3 | 473
Ion Channel 1 | 344

GO Process

proton transport 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase subunit s, mitochondrial ATP5S Tdark Enzyme -0.41218 1.48 122
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
Mitochondrial uncoupling protein 4 SLC25A27 Tbio Transporter -1.53936 38.0 51
NAD(P) transhydrogenase, mitochondrial NNT Tbio Enzyme -2.49624 309.2 112
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -1.04091 10.7 137
Sodium bicarbonate transporter-like protein 11 SLC4A11 Tbio Transporter -1.87650 77.5 77
ATP synthase subunit O, mitochondrial ATP5PO Tbio Enzyme -2.21731 177.4 106
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118
Brain mitochondrial carrier protein 1 SLC25A14 Tbio Transporter -1.45184 29.0 51